Tetrahydrofuran
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Medchemexpress LLC p-Ethynylphenylalanine hydrochloride | 188640-63-3 | 99.23% | 225.67 | 50 MG
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine hydrochloride) is a potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH).
- Click chemistry reagent.
- Contains an Alkyne group for CuAAc reactions.
- Selectively and reversibly inhibits the biosynthesis of serotonin.
- Decreases 5-HT and 5-HIAA levels in the rat midbrain (at 30 mg/kg; i.p.).
- Does not inhibit aromatic amino acid decarboxylase.
