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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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Vitamin K2 (Menaquinone) is an important fat-soluble vitamin that plays critical roles in protecting heart and brain and building strong bones It also plays an important role in cancer protection
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rel-Bedaquiline is a drug impurity related to the anti-tuberculosis agent bedaquiline and is supplied as an analytical reference for research use only. It is intended for chromatographic and analytical method development, impurity profiling, and stability studies. Consult the Certificate of Analysis for batch-specific purity and storage conditions.
Intended for research use only; not for human or clinical use.
Impurity standard for analytical and chromatographic method development.
High purity reference: 97.56% by HPLC (batch dependent).
Suitable for impurity profiling and stability studies.
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Vitamin K1 is a naturally occurring vitamin essential for blood coagulation and bone and vascular metabolism. It is a prenylated naphthoquinone synthesized by plants, green algae, and some cyanobacteria, acting as an electron carrier in photosystem I.
Required for blood coagulation and bone and vascular metabolism in humans
Shows significant antiproliferative effects and induces apoptosis in Caco-2, HT-29, and SW480 cell lines
Increased dietary intake is associated with a reduced risk of incident diabetes
Supplementation reverses high-fat diet-induced bone deterioration
Topical application suppresses pigmentation and resolves bruising, promoting wound repair
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Vitamin K4 is a chemically synthesized Vitamin K that plays an important role in the normal blood coagulation system. It arrests cells in the S phase of the cell cycle and induces apoptosis, and can be used for research on cancer, including prostate cancer and osteosarcoma.
Inhibits cell proliferation and induces caspase-dependent apoptosis in PC-3 cells.
Induces S phase cell cycle arrest in PC-3 and U2OS cells.
Inhibits the growth of U2OS cells.
Increases ROS generation and disrupts mitochondrial membrane potential in U2OS cells.
Inhibits the migration of U2OS cells in vitro.
Modulates expression of Bcl-2, Bax, PARP, and cleaved-caspase-3.
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Vitamin D Receptor Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting the Vitamin D Receptor. It is for research use only.
Immunohistochemistry-Paraffin (IHC-P): 1:100-500 dilution ratio
Immunohistochemistry-Frozen (IHC-F): 1:100-500 dilution ratio
Immunocytochemistry/Immunofluorescence (ICC/IF): 1:100-500 dilution ratio
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Elaidic acid-d9 is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. It is for research use only.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Vitamin E (D-alpha-Tocopherol) is a fat-soluble vitamin with potent antioxidant properties It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription
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Larixyl acetate is a diterpenoid research compound that inhibits TRPC6 channels and is used in cellular and animal studies of ion channel signaling, inflammation, cardiac hypertrophy, and traumatic brain injury. It is supplied as a powder (formula C22H36O3; MW 348.52 g/mol) and is intended for research use only.
Potent TRPC6 inhibitor (IC50 0.58 μM).
Also active against TRPC3 (IC50 6.83 μM).
High purity (99.5%).
Supplied as powder with multiple pack sizes, including 25 MG.
Recommended storage: powder at -20°C; solutions at -80°C for long-term.
Suitable for in vitro and in vivo pharmacology studies.
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Vitamin K1 (Standard) is the analytical standard of Vitamin K1. It is intended for research and analytical applications. Vitamin K1 is a naturally occurring vitamin that is required for blood coagulation and bone and vascular metabolism.
Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Analytical standard grade.
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Also available in 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 uM exhibits > 200-fold selectivity over other HDAC. purity: 99%
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