Prenol lipids
Medchemexpress LLC 18β-Glycyrrhetinic acid | 471-53-4 | 99.88% | 470.68 | 5 G
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and Glycyrrhizae Radix, known for its anti-ulcerative, anti-inflammatory, and antiproliferative properties. In vitro studies show it suppresses cell proliferation in a dose-dependent manner and influences PARP levels. In vivo, low-dose administration has demonstrated hepatoprotective effects against Triptolide-induced lesions and suppresses cytokine release.
- Exhibits anti-ulcerative, anti-inflammatory, and antiproliferative properties
- Suppresses cell proliferation in various cell lines in a dose-dependent manner
- Decreases full-length PARP levels and increases cleaved-PARP levels
- Demonstrates hepatoprotective effects against Triptolide-induced lesions in rats
- Suppresses cytokine release in animal models
- Applicable for cell assays with primary microglia cultures
- Suitable for animal administration studies
Medchemexpress LLC Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)- | 471-53-4 | 99.9% | 470.68 | 10 G
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
- Anti-ulcerative
- Anti-inflammatory
- Antiproliferative properties
Sigma Aldrich Fine Chemicals Biosciences L-Carvone >=97%, FCC, FG | 6485-40-1 | MFCD00001578 | 5KG
L-Carvone >=97%, FCC, FG | Purity: >=97% | Mol Wt: 150.22 | 6485-40-1 | MFCD00001578 | 5KG
Sigma Aldrich Fine Chemicals Biosciences D-Dihydrocarvone, mixture of isomers >=97%, FCC, FG | 7764-50-3 | MFCD00001636 | 100G
D-Dihydrocarvone, mixture of isomers >=97%, FCC, FG | Purity: >=97% | Mol Wt: 152.23 | 7764-50-3 | MFCD00001636 | 100G
Medchemexpress LLC Vasopressin, 8-L-ornithine-, acetate (salt) | 914453-98-8 | 99.6% | 1042.19 | 25 MG
Ornipressin acetate is a potent vasoconstrictor, hemostatic, and renal agent. It functions as a vasopressin agonist specific for the V1 receptor. This compound can be used as a local vasoconstrictor, can reverse hypotension associated with combined general/epidural anesthesia, and exhibits antidiuretic activity. Additionally, Ornipressin acetate reduces renal vascular resistance and enhances renal blood flow in renal failure models.
- Potent vasoconstrictor
- Hemostatic agent
- Renal agent
- Vasopressin V1 receptor agonist
- Can be used as a local vasoconstrictor
- Reverses hypotension associated with combined general/epidural anesthesia
- Exhibits antidiuretic activity
- Reduces renal vascular resistance
- Enhances renal blood flow in renal failure models
Apexbio Technology LLC Limonin 1180-71-8 100mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Enzo Life Sciences Tanshinone IIA (25mg). CAS: 568-72-9
Tanshinone IIA is a diterpenoid naphthoquinone found in the traditional Chinese medicine Tanshen (Salvia sp). It inhibits AP-1 activity by suppressing jun-fos-DNA complex formation (IC50=0.22 µM) and induces apoptosis in a variety of cell lines Purity: ≥93% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: +4°C.
Medchemexpress LLC Pramlintide acetate | 187887-46-3 | 99.9% | 3949.39 (free base) | 25 MG
Pramlintide acetate is a polypeptide analogue of human amylin. It acts as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer.
- Inhibits the growth of HCT-116 and HT-29 cells in a dose-dependent manner
- Demonstrates synergistic antiproliferative effects when combined with 5-fluorouracil, Oxaliplatin, or Irinotecan
Medchemexpress LLC Vitamin K1 2,3-epoxide | 25486-55-9 | 99.99% | 466.70 | 1 MG
Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1, which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. This compound is involved in blood clotting.
- Inactive metabolite form of Vitamin K1.
- Reduced to active vitamin by microsomal epoxide reductase.
- Involved in blood clotting.
Apexbio Technology LLC Pasireotide Acetate 396091-76-2 5mg
Pasireotide Acetate (CAS 396091-76-2) is a cyclohexapeptide somatostatin analog that acts as a multi-receptor ligand selectively activating several somatostatin receptor subtypes (sst1/2/3/5 with pKi values of 8 2 9 0 9 1 and 9 9 respectively) By modulating these receptors Pasireotide Acetate regulates the secretion of growth hormone insulin-like growth factor I (IGF-I) and adrenocorticotropic hormone (ACTH) at the cellular level Preclinical investigations indicate its capacity to alter endocrine hormone release with implications for studies in acromegaly and Cushing s disease Its demonstrated effects on secretion inhibition proliferation control and induction of apoptosis make it a valuable tool in studies of related biological pathways
Medchemexpress LLC Geniposide | 24512-63-8 | 99.55% | 388.37 | 100 MG
Geniposide is an iridoid glucoside extracted from *Gardenia jasminoidesEllis* fruits. It demonstrates a range of biological activities, including anti-diabetic, antioxidative, antiproliferative, and neuroprotective effects.
- Exhibits anti-thrombosis, anti-inflammation, and anti-diabetes activities.
- Demonstrates anti-atherosclerosis and anti-depression properties.
- Aids in healing Alzheimer's disease.
- Possesses anti-hypertension effects.
- Decreases blood glucose, insulin, and triglyceride levels in diabetic mice.
- Suppresses the expression of GP and G6Pase at both mRNA and protein levels.
- Reverses alcohol-induced elevation in serum ALT/AST and hepatic LPO levels.
- Upregulates the expression of heme oxygenase-1 (HO-1) to reduce cell apoptosis.
- Inhibits photochemistry-induced thromboembolism in vivo.
- Acts as a depressant on NF-κB by interrupting IκB degradation.
Sigma Aldrich Fine Chemicals Biosciences Carvacrol >=98%, FCC, FG | 499-75-2 | MFCD00002236 | 5KG
Carvacrol >=98%, FCC, FG | Purity: >=98% | Mol Wt: 150.22 | 499-75-2 | MFCD00002236 | 5KG