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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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7-iodo-7-deaza-2'-deoxyguanosine is a halogenated deoxyguanosine nucleoside analog used as a building block in nucleic acid chemistry. It is used in oligonucleotide synthesis and sequencing, and can be converted to its triphosphate form for enzymatic incorporation.
High purity: 99.8%.
Chemical formula: C11H13IN4O4.
Molecular weight: 392.15 g·mol⁻¹.
Suitable for DNA synthesis and sequencing applications.
Can be triphosphorylated for enzymatic incorporation into DNA.
Available as a 250 mg package.
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5-Iodo-CTP is a nucleotide analog derived from cytidine triphosphate (CTP) Due to its triphosphate structure it serves as a substrate for RNA polymerases and becomes incorporated into nascent RNA strands during transcription Incorporation of the iodine atom into RNA molecules facilitates their subsequent detection and analysis Thus 5-Iodo-CTP finds utility in studying RNA structure-function relationships analyzing RNA synthesis and stability and characterizing RNA-protein interactions Additionally the iodine substituent integrated within RNA offers a convenient handle for cross-linking or probing RNA-associated molecular events
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A nucleoside analog; inhibits the growth of P815 cells (IC50 = 14 µM), as well as sensitizes P815 cells to irradiation when used at a concentration of 1 µM
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