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Sulfadiazine (CAS 68-35-9) is a small-molecule inhibitor targeting dihydropteroate synthase It is designed to inhibit microbial folate biosynthesis thereby disrupting folic acid synthesis required for pathogen proliferation Sulfadiazine exerts its biological activity primarily through the competitive inhibition of dihydropteroate synthase In in vitro studies Sulfadiazine demonstrates antiparasitic activity with IC50 values ranging from approximately 2 g/mL to 5 g/mL against Toxoplasma gondii depending on experimental conditions and parasite strains Based on these pharmacological properties Sulfadiazine holds research potential in antiparasitic activity evaluation and studies of folic acid metabolism pathways
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Sulfapyridine (144-83-2) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It functions by inhibiting this enzyme thus blocking folic acid synthesis and suppressing bacterial growth Sulfapyridine exerts its biological activity primarily through inhibition of bacterial dihydropteroate synthase In in vitro studies sulfapyridine demonstrates inhibitory activity with IC50 values typically ranging from approximately 5 g/mL to 20 g/mL depending on the bacterial strain and assay conditions Based on these pharmacological properties sulfapyridine holds research potential in antimicrobial susceptibility testing investigations of bacterial resistance mechanisms and studies of bacterial folate pathway enzymes
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Sulfathiazole (CAS 72-14-0) is a small-molecule inhibitor targeting dihydropteroate synthase (DHPS) It is designed to competitively inhibit bacterial folic acid synthesis thereby disrupting the folate pathway and impeding microbial growth Sulfathiazole exerts its biological activity primarily through inhibition of DHPS In in vitro studies sulfathiazole demonstrates bacteriostatic inhibition with IC50 values ranging from low to medium micromolar concentrations depending on specific bacterial strains and experimental conditions Based on these pharmacological properties sulfathiazole holds research potential in investigating antibacterial resistance metabolic pathways of pathogens and enzyme-substrate interactions in microbiological and biochemical research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Sulfathiazole (CAS 72-14-0) is a small-molecule inhibitor targeting dihydropteroate synthase (DHPS) It is designed to competitively inhibit bacterial folic acid synthesis thereby disrupting the folate pathway and impeding microbial growth Sulfathiazole exerts its biological activity primarily through inhibition of DHPS In in vitro studies sulfathiazole demonstrates bacteriostatic inhibition with IC50 values ranging from low to medium micromolar concentrations depending on specific bacterial strains and experimental conditions Based on these pharmacological properties sulfathiazole holds research potential in investigating antibacterial resistance metabolic pathways of pathogens and enzyme-substrate interactions in microbiological and biochemical research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More