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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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1-Bromododecane-d25 is the deuterium labeled 1-Bromododecane. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Suitable for research use only
Potential to affect pharmacokinetic and metabolic profiles of drugs
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Azepan-2-one-d10 is a deuterium labeled compound designed for research applications. It serves as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. Deuteration of drug molecules can influence their pharmacokinetic and metabolic profiles, making this compound valuable for drug development studies.
Can be used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Facilitates studies on the effects of deuteration on pharmacokinetic and metabolic profiles of drugs
Incorporates stable heavy isotopes for quantitation during drug development
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Nonan-1-ol-d19 is a deuterium-labeled version of Nonan-1-ol. It is intended for research use only and is not sold to patients. The compound appears as a colorless to light yellow liquid. It should be stored at -20°C for up to 3 years in pure form, and in solvent at -80°C for 6 months or -20°C for 1 month.
Can be used as a tracer.
Suitable as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Deuterium substitution has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
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Aprepitant-d4 is the deuterium-labeled analogue of aprepitant, supplied as a powder and intended for use as a stable isotope internal standard in research and analytical laboratories, particularly for LC-MS quantitation.
Deuterium-labeled internal standard for quantitative LC-MS assays.
High chemical purity (99.0%).
Suitable molecular weight and isotopic composition for sensitive detection (MW 538.45).
Supplied as a stable powder with recommended storage at -20°C for long-term stability.
High solubility in DMSO (100 mg/mL); warming and sonication recommended.
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Olmesartan-d4 (RNH-6270-d4) is the deuterium-labeled version of Olmesartan, an angiotensin II receptor (AT1R) antagonist. It is primarily used to treat high blood pressure. This compound can serve as a tracer and an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
Used as a tracer for quantitation during drug development
Can be an internal standard for quantitative analysis
AT1 receptor antagonist
Deuterium-labeled compound
Suitable for NMR, GC-MS, or LC-MS applications
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Colchicine-d3 is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. It inhibits microtubule polymerization with an IC50 of 3 nM and is a competitive antagonist of the α3 glycine receptors (GlyRs). It is for research use only.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs; increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs
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