Triterpenoids
TARGETMOL CHEMICALS INC Betulinic acid 500MG
Also available in 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. Purity ≥98%
Cayman Chemical 23-hydroxy BetulInIc AcId 5mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Medchemexpress LLC HY-N0818 5mg Medchemexpress, Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98%
Medchemexpress, HY-N0818 5mg Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Glycyrrhetinic acid
Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Medchemexpress LLC Lupeol | 545-47-1 | 98.0% | 426.72 | 10 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC). It has several potential medicinal properties, like anticancer and anti-inflammatory activity.
- Potent androgen receptor (AR) inhibitor
- Anti-oxidant activity
- Anti-mutagenic activity
- Anti-tumor activity
- Anti-inflammatory activity
- Used for cancer research, especially prostate cancer
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.2% | 456.70 | C30H48O3 | 25 MG
Betulinic acid is a natural pentacyclic triterpenoid supplied as a high-purity analytical standard for research and laboratory assays. It is reported to inhibit eukaryotic topoisomerase I (IC50 ≈ 5 μM) and has documented anti-HIV, antimalarial, anti-inflammatory, and antitumor activities. The material is intended for qualitative and quantitative analysis in HPLC, GC, and MS and is provided in small pack sizes suitable for analytical workflows.
- High purity suitable for analytical assays.
- Validated for HPLC, GC, and MS methodologies.
- Provides a stable solid reference for quantitative analysis.
- Documented biological activity including topoisomerase I inhibition.
- Available in small pack sizes for laboratory use.