Acetic Acid
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Medchemexpress LLC Boc-NH-PEG7-acetic acid | 141282-29-3 | MFCD08274604 | 98.0% | 483.55 g/mol | C21H41NO11 | 100 MG
Boc-NH-PEG7-acetic acid is a polyethylene glycol-based linker designed for construction of proteolysis-targeting chimeras (PROTACs). It contains a Boc-protected amino terminus and an acetic acid terminus, enabling orthogonal deprotection and subsequent coupling to target ligands or E3 ligase binders. The PEG7 spacer increases solubility and provides conformational flexibility to optimize ternary complex formation during targeted protein degradation studies.
- Peg7 spacer improves solubility and provides a flexible linkage between ligands.
- Boc-protected amine allows selective deprotection and controlled conjugation.
- Acetic acid terminus enables standard amide or ester coupling chemistries.
- High purity minimizes side products and supports reproducible synthesis.
- Available in multiple package sizes for small-scale and scale-up work.
- Stable under sealed, low-temperature storage to preserve integrity.
