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![Medchemexpress LLC Sodium 2-[[4-[[(2S)-3-methyl-1-oxo-...carbamoyl]benzoyl]amino]acetate | 144055-55-0 | 99.1% | 592.54 g/mol | C26H32F3N4NaO7 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298375.png-250.jpg)
Medchemexpress LLC Sodium 2-[[4-[[(2S)-3-methyl-1-oxo-...carbamoyl]benzoyl]amino]acetate | 144055-55-0 | 99.1% | 592.54 g/mol | C26H32F3N4NaO7 | 10 MG
FK706 is a potent, slow-binding, competitive inhibitor of human neutrophil elastase used in biochemical and cellular research to study elastase activity and inflammation-related pathways. It is selective versus other serine proteases and has reported anti-inflammatory effects.
- Potent inhibitor of human neutrophil elastase (IC50 83 nM; Ki 4.2 nM).
- Active against mouse and porcine elastase (IC50s 22 nM and 100 nM).
- Selective versus other serine proteases such as trypsin, chymotrypsin, and cathepsin G.
- High purity (99.12%) and solid, white to off-white appearance.
- Soluble ≥100 mg/mL in water and 115 mg/mL in DMSO (sonication may be required).
- Molecular weight 592.54 g/mol; formula C26H32F3N4NaO7.
- Store sealed away from moisture; in solution: -80°C (6 months), -20°C (1 month).
