Tiglic acid is a monocarboxylic unsaturated organic acid that can be isolated from croton oil. It functions by agonizing FFA2 and upregulating PYY expression. Derivatives of Tiglic acid have shown anti-inflammatory activity, making it suitable for research into obesity, diabetes, and inflammatory diseases.
- Significantly upregulates PYY gene expression in NCI-h716 human enteroendocrine cell line.
- Can be isolated from croton oil.
- Agonizes FFA2.
- Upregulates PYY expression.
- Derivatives have anti-inflammatory activity.