Alkyl chlorides
![Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264388.png-250.jpg)
Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG
UC-112 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAP) developed for cellular studies of apoptosis and anticancer activity. It produces cytotoxic and antiproliferative effects across multiple human cancer cell lines and is supplied as a solid or as a DMSO solution for research applications.
- Potent IAP inhibitor with reported cell-assay IC50 = 0.7-3.4 μM.
- Demonstrated activity in PC-3, A-375, M14, and DU-145 cell lines.
- High purity (98.92%) suitable for in vitro studies.
- Molecular formula C22H24N2O2; molecular weight 348.44.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use in apoptosis and anticancer mechanism studies.
![Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidin-4-amine, N,1-diphenyl- | 68380-53-0 | 99.5% | 287.32 Da | C17H13N5 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289259.png-250.jpg)
Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidin-4-amine, N,1-diphenyl- | 68380-53-0 | 99.5% | 287.32 Da | C17H13N5 | 10 MG
Antifungal agent 112 (Compound 1e) is a purified small-molecule research compound that shows potent in vitro antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus (reported MICs 0.0024, 0.0022, and 0.0028 M, respectively). It is supplied as a high-purity powder, soluble in DMSO, and intended for laboratory research use.
- High purity suitable for research use.
- Potent in vitro activity against Candida and Aspergillus species.
- Soluble in DMSO at the concentrations described by the supplier.
- Stable as a powder when stored under recommended conditions.
- Available in small milligram pack sizes for laboratory experiments.
Cambridge Isotope Laboratories 1-Methylnaphthalene (unlabeled) 200 ug/mL in isooctane 1 2 mL
1-Methylnaphthalene (unlabeled) 200 ug/mL in isooctane 1 2 mL
Apexbio Technology LLC I-CBP 112 1640282-31-0 5mg
I-CBP 112 (CAS 1640282-31-0) is a selective small-molecule inhibitor targeting the bromodomains of CREBBP (CBP) and EP300 two epigenetic regulators involved in transcriptional control In biochemical assays I-CBP 112 demonstrates an IC50 of 170 nM against CREBBP with marked selectivity over other bromodomain-containing proteins such as ATAD2 BAZ2B and members of the BET family In vitro studies indicate that I-CBP 112 does not exhibit significant cytotoxicity in U2OS cells at concentrations up to 50 M Currently this compound is utilized predominantly in cellular and molecular studies to dissect the function of CREBBP/EP300 bromodomains in gene regulation with ongoing use limited to preclinical in vitro research contexts
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).
Medchemexpress LLC hsa-miR-122-5p mimic 20nmol | 20nmol
hsa-miR-122-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Medchemexpress LLC 2 3 5-Trichloro-4-py 500mg
2 3 5-Trichloro-4-pyridinol can be used as a herbicide for direct-seeded and flooded rice[1]
Matrix Scientific (DIFLUOROMETHYL)BENZENE-1G
(Difluoromethyl)benzene, 97%; 1g,C7H6F2, MFCD03788488, mw 128.12, [455-31-2]