Alkyl chlorides
Medchemexpress LLC Rapastinel Trifluoroacetate | 1435786-04-1 | 98.0% | 527.49 | 100 MG
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. It has potential for treating major depressive disorder and is currently in phase II clinical development as an adjunctive therapy for this condition. Studies have shown that Rapastinel Trifluoroacetate produces an antidepressant-like effect and an anxiolytic effect in animal models, without altering locomotor activity.
- NMDA receptor modulator with glycine-site partial agonist properties
- Potential for treating major depressive disorder
- Phase II clinical development as an adjunctive therapy
- Produces antidepressant-like and anxiolytic effects in animal models
- Does not alter locomotor activity
Medchemexpress LLC Spi-112 | 1051387-90-6 | 98.0% | 468.46 | C22H17FN4O5S | 5 MG
SPI-112 is a small-molecule, selective and competitive inhibitor of SHP2 (PTPN11) used for biochemical and cellular research. It inhibits SHP2 and related protein tyrosine phosphatases and is supplied as a solid with guidance for storage and preparation of solution stocks.
- Selective and competitive inhibition of SHP2 for pathway studies.
- Reported IC50 values support biochemical assay characterization.
- High purity solid suitable for preparation of DMSO stocks.
- Available in small milligram quantities and as a prepared solution for convenience.
- Storage recommendations provided to preserve compound stability.
Medchemexpress LLC 2 3 5-Trichloro-4-py 50mg
2 3 5-Trichloro-4-pyridinol can be used as a herbicide for direct-seeded and flooded rice[1]
Medchemexpress LLC 2 4 7-Trichloro-8-fl 100g
2 4 7-Trichloro-8-fluoropyrido[4 3-d]pyrimidine is a drug intermediate for synthesis of various active compounds
TARGETMOL CHEMICALS INC BSJ-04-122 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM respectively.BSJ-04-122 can be used for cancer research. purity: 97%
Cambridge Isotope Laboratories 3 5 6-Trichloro-2-pyridinol (TCPy) (4 5 6-13C3 99%) 100 ug/mL in acetonitrile 1 2 mL
3 5 6-Trichloro-2-pyridinol (TCPy) (4 5 6-13C3 99%) 100 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC 3,5,6-trichloro-2-pyridinol | 6515-38-4 | MFCD00130269 | 99.9% | 198.43 g·mol⁻¹ | C5H2Cl3NO | 5 G
3,5,6-Trichloro-2-pyridinol is a chlorinated pyridinol compound and a primary degradation metabolite of certain organophosphate insecticides and herbicides. It is provided for laboratory use as an analytical standard and for toxicology, environmental monitoring, and research applications.
- High purity suitable for analytical and toxicology studies.
- Available as solid in multiple gram sizes and as solution formats.
- Molecular formula C5H2Cl3NO; molecular weight 198.43 g·mol⁻¹.
- Characterized by LC-MS with a certificate of analysis for each batch.
- Suitable as a metabolite reference and environmental marker.
Medchemexpress LLC hsa-miR-122-5p mimic 5nmol | 5nmol
hsa-miR-122-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 50 MG
UC-112 is a survivin and XIAP modulator that demonstrates anticancer activity. It works by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal degradation pathway. It also reduces XIAP levels in in vivo tumor models, activates caspase-3/7 and caspase-9, and induces apoptosis in cancer cells. This product is for research use only and not for patient use.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9, inducing cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Inhibits human melanoma tumor growth in nude mice
Medchemexpress LLC 2(1H)-pyridinone, 3,5,6-trichloro- | 6515-38-4 | MFCD00130269, MFCD02313933 | 99.9% | 198.43 g/mol | C5H2Cl3NO | 1 G
3,5,6-Trichloro-2-pyridinol (TCPy) is the primary metabolite of several organophosphate pesticides and is supplied as a research-grade standard for analytical, metabolite, and toxicology studies. It is used as an analytical reference and for metabolism and exposure assessment research.
- High purity (reported 99.85%) suitable for analytical applications.
- Available as a solid and as a 10 mM solution in DMSO.
- Supplied with certificate of analysis and data sheet for quality assurance.
- Suitable for use as an analytical standard, metabolite reference, and in toxicology studies.
- Multiple pack sizes available to support small-scale and preparative workflows.
Medchemexpress LLC Rapastinel trifluoroacetate | 1435786-04-1 | MFCD20527320 | 98.0% | 527.49 | C20H32F3N5O8 | 10 MG
Rapastinel trifluoroacetate is a peptide-based NMDA receptor modulator used in preclinical research to investigate antidepressant-related mechanisms and receptor pharmacology. It is supplied as a white to off-white solid with high purity and defined storage recommendations.
- High purity (98.0%) suitable for research applications.
- Peptide NMDA receptor modulator with glycine-site partial agonist activity.
- White to off-white solid, convenient for formulation and dosing.
- Available in small milligram quantities for in vitro and in vivo studies.
- Recommended storage: sealed, away from moisture; in solvent -80°C (up to 6 months).
Cambridge Isotope Laboratories 3 5 6-Trichloro-2-pyridinol (TCPy) (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
3 5 6-Trichloro-2-pyridinol (TCPy) (unlabeled) 100 ug/mL in acetonitrile 1 2 mL