Aryl iodides
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Medchemexpress LLC 5-Iodo-indirubin-3'-monoxime | 331467-03-9 | 98.1% | 403.17 | 1 ML
5-Iodo-indirubin-3'-monoxime is a potent inhibitor of GSK-3β, CDK5/P25, and CDK1/cyclin B. It competes with ATP for binding to the catalytic site of the kinase, with IC50 values of 9, 20, and 25 nM, respectively. It is intended for research use only.
- Potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor
- Competes with ATP for binding to the catalytic site of the kinase
- IC50s of 9 nM (GSK-3β), 20 nM (Cdk5/p25), and 25 nM (Cdk1/cyclin B)
- For research use only
