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Filtered Search Results
Ambeed AMBEED
5000846979 3 3 - ETHANE-1 1-DIYL B 1G
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Ambeed AMBEED
5000891501 ANTHRACENE-910-DIYL DIAC 250MG
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MOLTOX Molecular Toxicology Inc 2-Aminoanthracene, 100 ug/vial, 5 vials/pack, Store in Refrigerator
For use in Ames test with the following corresponding tester strains and dosage: - TA1538. Dose 2 - 10 µg/plate. - TA97a, TA98, TA100. Dose 1 - 5 µg/plate. - TA102. Dose 5 - 10 µg/plate. - E. coli WP2, E. coli WP2 uvra, E. coli WP2 pKM101, E. coli WP2 uvra pKM101. Dose 20 µg/plate. Reconstitute with organic solvents such as DMSO or sterile dH2O as applicable. Indirect acting mutagens require the use of S9 metabolic activation to cause mutagenicity. CONTROLCHEM™ chemicals are obtained from major suppliers of research chemicals and are employed without further characterization or purification. Packaged quantities are precise within 1%. Please Note: CONTROLCHEM™ chemicals are known mutagens/carcinogens/toxins and are sold only to those experienced in the safe handling and disposal of hazardous materials. Consult your Institutional Safety Officer before ordering.
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Apexbio Technology LLC A 779 159432-28-7 1mg
A 779 (CAS 159432-28-7) is a selective antagonist of the angiotensin-(1-7)/Mas receptor By competitively inhibiting angiotensin-(1-7) a bioactive peptide of the renin-angiotensin system (RAS) involved in cardiovascular and renal homeostasis A 779 enables detailed study of Mas receptor-mediated signaling In vivo A 779 blocks the antidiuretic and pressor effects of angiotensin-(1-7) in rats and modulates the response to bradykinin potentiation by ACE inhibition It has been used to explore interactions among angiotensin receptors and the role of Mas signaling in cardiovascular and renal physiology
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Medchemexpress LLC A 779 | 159432-28-7 | 99.3% | 872.97 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A 779 is a specific antagonist of the G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII. It is for research use only.
- Inhibits the effect of Ang-(1-7)
- Suppresses PCNA protein expression up-regulated by Ang II
- Blocks Ang II-induced inflammatory responses of VSMCs
- Blocks Ang II-induced Akt and ERK1/2 phosphorylation
- Elevates serum BALP, CTX, TRAcP 5b, OC, and urinary DPD
- Abolishes Ang-(1-7)'s favorable effects on bone health by blocking the Mas receptor
- Erradicates captopril protective effects on bone metabolism, mineralization, and micro-structure
- Restores OVX effects on RANKL expression and ACE-1/AngII/AT1R cascade
- Down-regulates OPG expression and ACE-2/Ang1-7/Mas pathway
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eMolecules 229005-80-5 | TAK-779 | Ambeed | MFCD05662319 | 531.140 | C33H39ClN2O2 | 98.000 | [Cl-].Cc1ccc(cc1)-c1ccc2CCCC(=Cc2c1)C(=O)Nc1ccc(C[N+](C)(C)C2CCOCC2)cc1 | 25mg | 832562838
TAK-779 | Ambeed | 229005-80-5 | MFCD05662319 | 531.140 | C33H39ClN2O2 | 98.000 | [Cl-].Cc1ccc(cc1)-c1ccc2CCCC(=Cc2c1)C(=O)Nc1ccc(C[N+](C)(C)C2CCOCC2)cc1 | 25mg | 832562838
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eMolecules 117820-97-0 | 2,3-Dibromoanthracene | Toronto Research Chemicals | MFCD30497387 | 336.026 | C14H8Br2Brc1cc2cc3ccccc3cc2cc1Br | 50mg | 483399302
2,3-Dibromoanthracene | Toronto Research Chemicals | 117820-97-0 | MFCD30497387 | 336.026 | C14H8Br2Brc1cc2cc3ccccc3cc2cc1Br | 50mg | 483399302
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Medchemexpress LLC (2S)-N-[7-chloro-6-[4-[(3R,4R)-4-hydroxy-3-methyloxolan-3-yl]piperazin-1-yl]isoquinolin-3-yl]-6-o... | 2769107-89-1 | 99.7% | 501.02 g·mol⁻1 | C26H33ClN4O4 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MK-1468 is an orally active, selective, blood-brain barrier-permeable inhibitor of leucine-rich repeat kinase 2 (LRRK2) used in preclinical research of Parkinson's disease and LRRK2-related pathways.
- Orally active and brain-penetrant LRRK2 inhibitor suitable for in vivo and in vitro studies.
- High purity (≈99.7%) for research-grade experiments.
- Molecular weight 501.02 g·mol⁻1 and formula C26H33ClN4O4.
- Available in small-scale quantities for dosing and assay optimization.
- Store powder at -20°C; solutions stable at -80°C for 6 months.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC A 779 159432-28-7 5mg
A 779 (CAS 159432-28-7) is a selective antagonist of the angiotensin-(1-7)/Mas receptor By competitively inhibiting angiotensin-(1-7) a bioactive peptide of the renin-angiotensin system (RAS) involved in cardiovascular and renal homeostasis A 779 enables detailed study of Mas receptor-mediated signaling In vivo A 779 blocks the antidiuretic and pressor effects of angiotensin-(1-7) in rats and modulates the response to bradykinin potentiation by ACE inhibition It has been used to explore interactions among angiotensin receptors and the role of Mas signaling in cardiovascular and renal physiology
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 9-Bromoanthracene | ≥97% | CAS 1564-64-3 | C14H9Br | 1kg
9-Bromoanthracene | ≥97% | CAS 1564-64-3 | C14H9Br | 1kg
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Medchemexpress LLC TAK-779 100 mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TAK-779 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC TAK-779 10MM 1ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TAK-779 10MM 1ML
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AARON CHEMICALS LLC
NC4011756 44 ETHENE 1 2 DIYL DIB 5KG
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Medchemexpress LLC MK-1468 25 mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MK-1468 25MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 1-(Benzylsulfonyl)-4-bromobenzene | ≥97% | CAS 100375-03-9 | C13H11BrO2S | 500mg
1-(Benzylsulfonyl)-4-bromobenzene | ≥97% | CAS 100375-03-9 | C13H11BrO2S | 500mg
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