Apexbio Technology LLC KDM5-C70-5MG
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KDM5-C70 (CAS No 1596348-32-1) is a potent small molecule inhibitor used in the field of epigenetics research primarily targeting the Jumonji C (JmjC) domain-containing histone demethylases It inhibits the KDM5 family of enzymes which are crucial in regulating gene expression through histone modification processes The compound exhibits in vitro activity in the nanomolar to low micromolar range and is often utilized in studies exploring cellular and molecular mechanisms of cancer as well as in drug discovery and development for oncology therapeutics Various cell models including cancer cell lines are frequently employed to investigate its effects on gene expression and cellular proliferation Animal studies further elucidate its pharmacokinetic and pharmacodynamic properties Experimental concentrations typically depend on the specific research design allowing flexibility for diverse experimental setups