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Filtered Search Results
Ambeed AMBEED
5000886537 26-DIHYDROXYNAPHTHALENE 25G
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Medchemexpress LLC Carmoxirole hydrochloride | 115092-85-8
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Carmoxirole hydrochloride | 115092-85-8
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Medchemexpress LLC Tamsulosin (hydrochloride) | 106463-17-6 | 99.8% | 25 MG
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Tamsulosin hydrochloride is an orally active antagonist of the α1-adrenergic receptor. It induces apoptosis and is used for research related to prostatic hyperplasia. It also attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models.
- Orally active α1-adrenergic receptor antagonist
- Induces apoptosis
- Used for research of prostatic hyperplasia
- Attenuates abdominal aortic aneurysm growth
- Inhibits inflammation in animal models
- Stable under recommended storage conditions
- White to off-white solid appearance
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Accela Chembio Inc 7-nitro-1-tetralone | 5g | 40353-34-2 | MFCD00019661 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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7-nitro-1-tetralone | 5g | 40353-34-2 | MFCD00019661 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Alkali Scientific 4 Chloro 1 Naphthol, 25 G
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Chloro-naphthol is a chromogenic reagent used in biochemical assays, particularly in enzyme detection and blotting procedures. The reagent reacts with alkaline phosphatase and other phosphatases to form a colored precipitate, making it an essential tool in various laboratory techniques, including immunoblotting, enzyme-linked assays, and histochemical staining. This 25g bottle is ideal for preparing multiple solutions for large-scale assays and laboratory research. It is commonly used in molecular biology and microbiology for detecting specific enzymes and proteins, helping scientists identify bacterial species and detect changes in gene expression or enzyme activity in a variety of sample types.
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Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | MFCD00150062 | 99.2% | 262.73 | 25 MG
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Neocuproine hydrochloride monohydrate can be used to prepare complex solutions for studying antioxidant capacity determination in biological samples based on copper reduction complexes.
- Appearance: solid
- Color: off-white to light yellow
- Handling instructions: store at room temperature, keep dry and cool. In solvent: -80°C 1 year, -20°C 6 months.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000700976 NAPHTHOL AS-OL 50G
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Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 25 MG
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Givinostat hydrochloride monohydrate is a potent HDAC inhibitor, demonstrating IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3. This compound is notable for its ability to penetrate the blood-brain barrier, making it suitable for a range of research applications.
- Potent HDAC inhibitor for HDAC1 and HDAC3
- Penetrates the blood-brain barrier
- Suppresses LPS-induced IL-1β and IL-6 production
- Inhibits JS-1 cell proliferation
- Reduces serum TNFα and IL-1β levels in vivo
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Apexbio Technology LLC Adapalene 106685-40-9 100mg
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Adapalene (106685-40-9) is a small-molecule agonist targeting retinoic acid receptor subtypes RAR and RAR with lower affinity for RAR and minimal activity toward RXR It is designed to selectively modulate retinoic acid receptor-mediated gene transcription thereby regulating cellular growth differentiation and apoptosis Adapalene exerts its biological activity primarily through selective activation of RAR and RAR subtypes In experimental models adapalene exhibits agonistic activity with Ki values of 2 3 nM for RAR 9 3 nM for RAR and 22 nM for RAR Based on these pharmacological properties adapalene holds research potential in investigating retinoid signaling pathways cellular proliferation apoptosis and antitumor mechanisms particularly in colorectal cancer models
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Ambeed AMBEED
5000867214 1-BROMO-4-NITRONAPHTHALENE 1GR
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Selleck Chemical LLC 1-Hydroxy-2-naphthoic acid
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1-Hydroxy-2-naphthoic acid is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms
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Medchemexpress LLC Benzenesulfonamide, 4-[(6-amino-4-pyrimidinyl)amino]-, hydrochloride (1:1) | 21886-12-4 | 99.6% | 301.75 | 25 MG
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PNU112455A hydrochloride is an ATP-competitive inhibitor of CDK2 and CDK5. It binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively. This product is for research use only and is not sold to patients.
- ATP-competitive CDK2 and CDK5 inhibitor.
- Binds to the ATP site of CDK2 and CDK5.
- Purity: 99.56%.
- Available in various sizes and concentrations, including solid and solution forms.
- Soluble in DMSO and H2O.
- Provided with detailed solubility and storage information for both in vitro and in vivo applications.
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Medchemexpress LLC Rotigotine Hydrochloride | 125572-93-2 | 99.5% | C19H26ClNOS | 100 MG
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Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. It exhibits Ki values of 0.71 nM for the dopamine D3 receptor, 4-15 nM for D2, D5, and D4 receptors, and 83 nM for the dopamine D1 receptor.
- Full agonist at dopamine receptors, partial agonist at 5-HT1A receptor, and antagonist at α2B-adrenergic receptor.
- Shows selectivity for D3 receptors (10-fold over D2, D4, D5, and 100-fold over D1).
- Functionally acts as a full agonist at all dopamine receptors.
- Decreases THir neurons in primary mesencephalic cell culture.
- Neuroprotective effects against MPP+ toxicity and rotenone-induced cell death.
- Inhibits ROS production by rotenone.
- For research use only.
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Medchemexpress LLC 4-[4-[(dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one | 1883429-22-8 | MFCD30182324 | 98.7% | 353.41 Da | C20H23N3O3 | 50 MG
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BI-9564 is a small-molecule chemical probe that selectively inhibits BRD9 and, to a lesser extent, BRD7 bromodomains. It is cell-permeable, exhibits high affinity for BRD9, and has been used in both in vitro and in vivo studies to probe BAF complex biology and bromodomain function.
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Enzo Life Sciences Gossypol (100mg). CAS: 303-45-7
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Mixture of ~65% (+)- and ~35% (-)-enantiomers. Male antifertility agent with antispermatogenic activity. Shows antitumor, antiviral and antioxidant actions. Small molecule inhibitor of Bcl-2/Bcl-XL. Induces apoptosis. Synergizes with radiation and chemotherapy in vitro. Reversible inhibitor of protein phosphatase 2B (PP2B; calcineurin). Protein kinase C (PKC) inhibitor. Inhibits activities of the mitotic kinesin Eg5 (IC50=10.8µM/L). Inhibits RBL-1, 5-lipoxygenase (IC50=0.3µM) and 12-lipoxygenase (IC50=0.7µM). Inhibits PAF and leukotriene-induced guinea pig parenchyma contractions. Novel direct-acting inhibitor of calcineurin. Alternative name: 2,2'-bis[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]. Purity: ≥90% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml), dimethylformamide (25mg/ml), acetone or DMSO; sparingly soluble in methanol (2mg/ml); insoluble in water. Long Term Storage: -20°C.
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