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Filtered Search Results
Medchemexpress LLC Cysteamine (hydrochloride) | 156-57-0 | 99.3% | C2H8ClNS | 25 G
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Cysteamine hydrochloride is an orally active agent for treating nephropathic cystinosis and functions as an antioxidant. It elevates intracellular glutathione in cystinotic cells, restoring redox balance and mitigating apoptosis. The compound also exhibits antioxidant properties by scavenging reactive oxygen species and boosting glutathione production, and it enhances the production of heat shock proteins.
- Treats nephropathic cystinosis and acts as an antioxidant.
- Increases intracellular glutathione levels in cystinotic cells.
- Counteracts increased apoptosis in cystinotic cells.
- Scavenges OH, HOCl, and reacts with H2O2.
- Enhances production of heat shock proteins (HSP).
- Exerts dose-dependent effect on doxorubicin-induced cancer cell death.
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Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 MG
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BI-2865 is a non-covalent pan-KRAS inhibitor. It binds to wild-type (WT) and several mutant KRAS forms, including G12C, G12D, G12V, and G13D, with KDs ranging from 4.3 to 32 nM. This compound effectively inhibits the proliferation of G12C, G12D, or G12V mutant KRAS expressing BaF3 cells, showing a mean IC50 of approximately 140 nM.
- Binds to multiple KRAS mutants (WT, G12C, G12D, G12V, G13D)
- Inhibits proliferation of KRAS mutant expressing BaF3 cells
- Derivative with a prolinol substituent and a pyrimidine linker
- Exhibits direct ionic interaction with E62 and a water-mediated hydrogen bond network
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Medchemexpress LLC Atrasentan hydrochloride | 195733-43-8 | C29H39ClN2O6 | 100 MG
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Atrasentan hydrochloride is a selective endothelin A receptor antagonist, exhibiting an IC50 of 0.0551 nM for ETA. It is designated for research purposes only and is not intended for patient use. This compound presents as an off-white to gray solid with a molecular weight of 547.08.
- Effectively inhibits the growth of LNCaP and C4-2b prostate cancer cells.
- Significantly induces several CYPs and drug transporters.
- Acts as a moderate P-gp inhibitor and a weak BCRP inhibitor.
- Suppresses pressor response initiated by big endothelin-1 in pithed rats.
- Partially inhibits C4-2b tumor progression within the bone environment in the SCID-hu model.
- Soluble in DMSO and water with specific preparation requirements.
- Recommended storage at 4°C in sealed conditions, away from moisture.
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AdipoGen Sodium 2 3-dihydroxyisovalerat
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Chemical. CAS 74294-97-6 anhydrous. Formula C5H9NaO4 . H2O. MW 156.1 . 18.0. Synthetic. Racemic form of intermediate in L-valine catabolism and anabolism.
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AdipoGen 3Me-Sulfobutyl-benzindolium
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Chemical. CAS 63149-24-6. Formula C19H23NO3S. MW 345.46. Synthetic. Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.
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Research Products International Corp 4-Chloro-1-Naphthol, 25 Grams
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- CAS Numbers: 604-44-4
- Molecular Formula: C10H7OCl
- Molecular Weight: 178.61
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AdipoGen 4-Trifluoroacetylbenzoyl Cl
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Chemical. CAS 58808-60-9. Formula C9H4ClF3O2. MW 236.58. Synthetic. Building block for synthesis.
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AdipoGen 3 4-Epoxycyclohex-1-en
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Chemical. CAS 6705-51-7. Formula C6H8O. MW 96.13. Synthetic. Building block for synthesis.
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AdipoGen 2-Bromocycloheptanone
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Chemical. CAS 766-65-4. Formula C7H11BrO. MW 191.07. Synthetic. Building block for synthesis.
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AdipoGen 3-Bromo-1-butyne
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Chemical. CAS 18668-72-9. Formula C4H5Br. MW 132.99. Synthetic. Building block for synthesis.
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AdipoGen 9-Methylguanine
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Chemical. CAS 5502-78-3. Formula C6H7N5O. MW 165.15. Synthetic Nucleic acid base useful for synthesis and complex building. Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
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AdipoGen S S-EDDS-Na3
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Chemical. CAS 178949-82-1. Formula C10H13N2Na3O8. MW 358.19. Synthetic Aminopolycarboxylic acid. A powerful, readily biodegradable chelant. Complexing agent, exhibiting superior biological degradation environmentally friendly compared to EDTA. Used in cosmetic formulations, as effective anti-oxidant and water hardness control, to reduce radical generation, as effective peroxide stabiliser, as preservative potentiator improving piocide efficacy and excellent transition metal chelator.
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AdipoGen 9 10-Anthracenediyl-bismethyl
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Chemical. CAS 307554-62-7. Formula C22H18O8. MW 410.37. Synthetic. Reagent for the assay of O2 with better characteristics than 9,10-anthracenediyl-bis-dipropionic acid.
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AdipoGen 2-Chlorocyclohepta-trienone
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Chemical. CAS 3839-48-3. Formula C7H5ClO. MW 140.57. Synthetic. Building block for synthesis.
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AdipoGen 2 2-Dimethylcyclopentanone
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Chemical. CAS 4541-32-6. Formula C7H12O. MW 112.17. Synthetic. Building block for synthesis.
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