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Filtered Search Results
Selleck Chemical LLC BI-4464
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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM
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eMolecules 1141-38-4 | Naphthalene-2,6-dicarboxylic acid | Apollo Scientific US - Building Blocks | MFCD00004105 | 216.192 | C12H8O4 | 98.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 5g | 397996059
Naphthalene-2,6-dicarboxylic acid | Apollo Scientific US - Building Blocks | 1141-38-4 | MFCD00004105 | 216.192 | C12H8O4 | 98.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 5g | 397996059
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Ambeed AMBEED
5000868115 8-BROMO-1234-TETRAHYDROISO 1GR
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Medchemexpress LLC 1,8-naphthyridine-1(2H)-carboxamide, 3,4-dihydro-6-[5-(methoxymethyl)-3-pyridinyl]- | 1633009-87-6 | 99.2% | 298.34 g·mol-1 | C16H18N4O2 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI 689648 is a small-molecule, highly selective aldosterone synthase (CYP11B2) inhibitor used in preclinical research. It potently inhibits CYP11B2 while showing substantially less activity against CYP11B1, and is supplied with molecular characterization, purity data, and solubility/formulation guidance for in vitro and in vivo studies.
- Potent aldosterone synthase inhibition (IC50 2.1 nM).
- Reduced activity against CYP11B1 (IC50 310 nM) for improved selectivity.
- Characterized molecular data (C16H18N4O2; MW 298.34 g·mol-1).
- High purity suitable for research use (99.2% by LCMS).
- Documented solubility and formulation guidance for DMSO and in vivo vehicles.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369718 DOBUTAMINE HYDROCHL 10MM 1ML
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Medchemexpress LLC Encenicline hydrochloride | 550999-74-1 | C16H18Cl2N2OS | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Encenicline hydrochloride is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs), primarily for research use. It exhibits high selectivity for α7 nAChRs and demonstrates good brain penetration.
- Acts as a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors
- Exhibits selectivity for α7 nAChRs
- Demonstrates good brain penetration and adequate exposure time
- Restores memory function in scopolamine-treated rats
- Investigated in clinical trials for conditions like Alzheimer's disease, dementia, and schizophrenia
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Aobchem AOBCHEM
5000864318 2- 4-BROMOPHENYL METHOXY -1 3
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Apexbio Technology LLC Linagliptin (BI-1356) 668270-12-0 50mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Linagliptin (BI-1356 CAS 668270-12-0) is a potent competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) demonstrating IC50 values of 0 4 1 1 nM in multiple in vitro assays using DPP-4 extracted from Caco-2 cells DPP-4 is a membrane-bound and soluble protease involved in the degradation of incretin hormones such as GLP-1 which enhance pancreatic -cell glucose sensitivity and insulin secretion Linagliptin displays marked selectivity for DPP-4 over related peptidases and serine proteases In vivo linagliptin dose-dependently inhibits plasma DPP-4 activity and sustains glycemic control with prolonged effects observed at pharmacologically relevant doses This compound is widely utilized in studies of glucose metabolism and -cell function
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eMolecules 252562-80-4 | 4-(Tributylstannyl)-2-(trimethylsilyl)thiazole | Synthonix - Stock | MFCD01319064 | 446.360 | C18H37NSSiSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1csc(n1)[Si](C)(C)C | 500mg | 525924306
4-(Tributylstannyl)-2-(trimethylsilyl)thiazole | Synthonix - Stock | 252562-80-4 | MFCD01319064 | 446.360 | C18H37NSSiSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1csc(n1)[Si](C)(C)C | 500mg | 525924306
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Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Givinostat hydrochloride monohydrate is a potent histone deacetylase (HDAC) inhibitor, demonstrating inhibitory activity against HDAC1 (IC50 of 198 nM) and HDAC3 (IC50 of 157 nM). It can penetrate the blood-brain barrier (BBB), making it suitable for neurological research.
- Potent HDAC inhibitor targeting HDAC1 and HDAC3.
- Can penetrate the blood-brain barrier (BBB).
- Suitable for in vitro and in vivo studies related to HDAC inhibition.
- Available as a stable hydrochloride monohydrate form.
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eMolecules 1115492-92-6 | 2-Methyl-4-pyridylzinc bromide, 0.25 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cc([Zn+])ccn1 | 100ml | 532652893
2-Methyl-4-pyridylzinc bromide, 0.25 M in THF | Synthonix | 1115492-92-6237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cc([Zn+])ccn1 | 100ml | 532652893
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eMolecules 308796-17-0 | 2-Isopropylphenylzinc iodide, 0.50 M in THF | Synthonix311.470 | C9H11IZn | 0.000 | [I-].CC(C)c1ccccc1[Zn+] | 50ml | 532652871
2-Isopropylphenylzinc iodide, 0.50 M in THF | Synthonix | 308796-17-0311.470 | C9H11IZn | 0.000 | [I-].CC(C)c1ccccc1[Zn+] | 50ml | 532652871
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eMolecules 544429-21-2 | 3,4-Difluorophenylzinc iodide, 0.50 M in THF | Synthonix305.370 | C6H3F2IZn | 0.000 | [I-].Fc1ccc([Zn+])cc1F | 100ml | 532652775
3,4-Difluorophenylzinc iodide, 0.50 M in THF | Synthonix | 544429-21-2305.370 | C6H3F2IZn | 0.000 | [I-].Fc1ccc([Zn+])cc1F | 100ml | 532652775
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eMolecules 352525-72-5 | 4-Fluoro-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01319871 | 301.410 | C7H6FIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1F | 100ml | 532652844
4-Fluoro-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | 352525-72-5 | MFCD01319871 | 301.410 | C7H6FIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1F | 100ml | 532652844
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 312692-96-9 | 2,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix297.440 | C8H9IZn | 0.000 | [I-].Cc1ccc(C)c([Zn+])c1 | 100ml | 532652761
2,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix | 312692-96-9297.440 | C8H9IZn | 0.000 | [I-].Cc1ccc(C)c([Zn+])c1 | 100ml | 532652761
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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