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Filtered Search Results
eMolecules [4-Cyano-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |315.400 | C8H3BrF3NZn | 98.000 | [Br-].FC(F)(F)c1cc(ccc1[Zn+])C#N | 50ml | 818572015
[4-Cyano-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |315.400 | C8H3BrF3NZn | 98.000 | [Br-].FC(F)(F)c1cc(ccc1[Zn+])C#N | 50ml | 818572015
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Medchemexpress LLC Buparlisib Hydrochloride | 1312445-63-8 | C18H22ClF3N6O2 | 1 ML
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Buparlisib Hydrochloride (BKM120 Hydrochloride) is a CNS-penetrant pan-class I PI3K inhibitor with IC50 values of 52 nM for p110α, 166 nM for p110β, 116 nM for p110δ, and 262 nM for p110γ. It induces dose- and time-dependent apoptosis in multiple myeloma cell lines.
- Active against class I PI3K's, including common p110α mutants
- Lower potency against class III and IV PI3K's
- Induces dose-dependent growth inhibition in multiple myeloma cell lines
- Oral administration leads to dose-dependent modulation of pAKTSer473 in xenograft tumors
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Medchemexpress LLC 2-(2-chlorophenyl)-2-(5,7-dichloro-3-(hydroxymethyl)-4,6-dimethyl-1H-indol-2-yl)-N-((4-methylphenyl)su | 2244452-09-1 | 99.6% | 499.36 g/mol | C21H20Cl2N2O6S | 1MG
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BI-4924 is a potent, selective small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) used in biochemical and cellular research to probe serine biosynthesis and PHGDH-dependent metabolism. The compound is a hydroxymethylene-bearing carboxylic acid derivative (CAS 2244452-09-1) with characterized physicochemical and solubility properties.
- Potent PHGDH inhibition: IC50 = 3 nM.
- Disrupts serine biosynthesis in cells (IC50 ≈ 2.2 μM at 72 h).
- Chemical formula C21H20Cl2N2O6S; molecular weight 499.36 g/mol.
- High purity: 99.6% (reported by supplier).
- Form: powder; suitable for DMSO stock solutions.
- Solubility in vitro: DMSO 125 mg/mL (≈250 mM; ultrasonic recommended).
- In vivo formulations documented for multiple vehicles at ≥2.08 mg/mL.
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eMolecules 1610827-42-3 | Tetradecylzinc bromide, 0.50 M in THF | Synthonix342.670 | C14H29BrZn | 0.000 | [Br-].CCCCCCCCCCCCCC[Zn+] | 100ml | 532653005
Tetradecylzinc bromide, 0.50 M in THF | Synthonix | 1610827-42-3342.670 | C14H29BrZn | 0.000 | [Br-].CCCCCCCCCCCCCC[Zn+] | 100ml | 532653005
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eMolecules 1,3-Benzothiazol-6-ylmagnesium bromide, 0.5 M in THF | Synthonix |238.390 | C7H4BrMgNS | 0.000 | [Br-].[Mg+]c1ccc2ncsc2c1 | 50ml | 818572001
1,3-Benzothiazol-6-ylmagnesium bromide, 0.5 M in THF | Synthonix |238.390 | C7H4BrMgNS | 0.000 | [Br-].[Mg+]c1ccc2ncsc2c1 | 50ml | 818572001
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eMolecules 1841131-63-2 | Anthracen-9-ylzinc bromide, 0.25 M in THF | Synthonix322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1c2ccccc2cc2ccccc12 | 50ml | 818571999
Anthracen-9-ylzinc bromide, 0.25 M in THF | Synthonix | 1841131-63-2322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1c2ccccc2cc2ccccc12 | 50ml | 818571999
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eMolecules 476167-07-4 | 3-Cyanophenylzinc bromide, 0.50 M in THF | Synthonix247.400 | C7H4BrNZn | 0.000 | [Br-].[Zn+]c1cccc(c1)C#N | 100ml | 702445876
3-Cyanophenylzinc bromide, 0.50 M in THF | Synthonix | 476167-07-4247.400 | C7H4BrNZn | 0.000 | [Br-].[Zn+]c1cccc(c1)C#N | 100ml | 702445876
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eMolecules 97674-02-7 | Tributyl(1-ethoxyvinyl)stannane | Synthonix - Stock | MFCD00010240 | 361.157 | C16H34OSn | 98.000 | CCCC[Sn](CCCC)(CCCC)C(=C)OCC | 1g | 525924149
Tributyl(1-ethoxyvinyl)stannane | Synthonix - Stock | 97674-02-7 | MFCD00010240 | 361.157 | C16H34OSn | 98.000 | CCCC[Sn](CCCC)(CCCC)C(=C)OCC | 1g | 525924149
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eMolecules 737797-36-3 | 5-Chloro-2-methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260171 | 333.860 | C7H6ClIOZn | 0.000 | [I-].COc1ccc(Cl)cc1[Zn+] | 100ml | 532652719
5-Chloro-2-methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | 737797-36-3 | MFCD02260171 | 333.860 | C7H6ClIOZn | 0.000 | [I-].COc1ccc(Cl)cc1[Zn+] | 100ml | 532652719
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eMolecules 260-94-6 | Acridine | Combi-Blocks | MFCD00005025 | 179.222 | C13H9N | 98.000 | c1ccc2nc3ccccc3cc2c1 | 5g | 267203991
Acridine | Combi-Blocks | 260-94-6 | MFCD00005025 | 179.222 | C13H9N | 98.000 | c1ccc2nc3ccccc3cc2c1 | 5g | 267203991
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428948 BI-27 SERUM-FREE SUP 50ML
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TARGETMOL CHEMICALS INC BI-882370 10MG
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Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases. Purity 99.07%
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eMolecules 1013082-37-5 | Tributyl(3,5-dimethylphenyl)stannane | Synthonix - Stock395.218 | C20H36Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)c1cc(C)cc(C)c1 | 10g | 525924571
Tributyl(3,5-dimethylphenyl)stannane | Synthonix - Stock | 1013082-37-5395.218 | C20H36Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)c1cc(C)cc(C)c1 | 10g | 525924571
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eMolecules 103408-63-5 | 5-Tributylstannyl-1,3-dimethyluracil | Synthonix - Stock | MFCD01318970 | 429.192 | C18H34N2O2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cn(C)c(=O)n(C)c1=O | 1g | 525924023
5-Tributylstannyl-1,3-dimethyluracil | Synthonix - Stock | 103408-63-5 | MFCD01318970 | 429.192 | C18H34N2O2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cn(C)c(=O)n(C)c1=O | 1g | 525924023
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AdipoGen Naphthol AS
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Chemical. CAS 92-77-3. Formula C17H13NO2. MW BD9837. Naphthol AS 3-Hydroxy-2-naphthanilide is a fluorescent dye commonly used as a building block or intermediate to produce fluorigenic substrates, bioactive chemicals or as a coupling reagent to produce azo dyes. After cleavage of the fluorigenic substrates by esterases the free Naphthol AS can couple with diazonium salts to form different types of fluorescent azo dyes. 3-Hydroxy-2-naphthanilide 3HNA is also a naturally occurring chemical that can be found in human urine. It is used as a marker for early pregnancy.
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