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Filtered Search Results
eMolecules 41842-29-9 | 2-Ethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD14635268 | 225.368 | C8H9BrMgO | 0.000 | [Br-].CCOc1ccccc1[Mg+] | 100ml | 437237192
2-Ethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 41842-29-9 | MFCD14635268 | 225.368 | C8H9BrMgO | 0.000 | [Br-].CCOc1ccccc1[Mg+] | 100ml | 437237192
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eMolecules 413589-34-1 | 3-Chloro-4-fluorophenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD02260212 | 233.750 | C6H3BrClFMg | 0.000 | [Br-].Fc1ccc([Mg+])cc1Cl | 50ml | 437237043
3-Chloro-4-fluorophenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 413589-34-1 | MFCD02260212 | 233.750 | C6H3BrClFMg | 0.000 | [Br-].Fc1ccc([Mg+])cc1Cl | 50ml | 437237043
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eMolecules 460747-53-9 | 4-Chloro-3-methylphenylmagnesium bromide, 0.50 M in THF | Synthonix - Stock | MFCD02260216 | 229.780 | C7H6BrClMg | 0.000 | [Br-].Cc1cc([Mg+])ccc1Cl | 100ml | 437237041
4-Chloro-3-methylphenylmagnesium bromide, 0.50 M in THF | Synthonix - Stock | 460747-53-9 | MFCD02260216 | 229.780 | C7H6BrClMg | 0.000 | [Br-].Cc1cc([Mg+])ccc1Cl | 100ml | 437237041
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eMolecules 105494-65-3 | Tri-n-butyl(1-propenyl)tin E and Z | Synthonix - Stock | MFCD03425868 | 331.131 | C15H32Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\C | 1g | 525924261
Tri-n-butyl(1-propenyl)tin E and Z | Synthonix - Stock | 105494-65-3 | MFCD03425868 | 331.131 | C15H32Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\C | 1g | 525924261
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Medchemexpress LLC PNU112455A hydrochloride | 21886-12-4 | 99.6% | 301.75 | 1 ML
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PNU112455A hydrochloride is an ATP-competitive inhibitor of CDK2 and CDK5. It binds to the ATP site of CDK2 and CDK5 with Km values of 3.6 μM and 3.2 μM, respectively. This product is intended for research use only and is not sold to patients.
- ATP-competitive CDK2 and CDK5 inhibitor.
- Binds to the ATP site of CDK2 and CDK5.
- Km for CDK2: 3.6 μM.
- Km for CDK5: 3.2 μM.
- Purity: 99.56%.
- Appearance: Solid, Light yellow to yellow.
- Shipping: Room temperature in continental US.
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month.
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eMolecules 118486-95-6 | 5-Methyl-2-(tributylstannyl)furan | Synthonix - Stock | MFCD01319081 | 371.152 | C17H32OSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(C)o1 | 5g | 525920518
5-Methyl-2-(tributylstannyl)furan | Synthonix - Stock | 118486-95-6 | MFCD01319081 | 371.152 | C17H32OSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(C)o1 | 5g | 525920518
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Medchemexpress LLC Givinostat hydrochloride | 199657-29-9 | MFCD28502062 | 98.1% | 457.95 | 100 MG
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Givinostat hydrochloride is a Histone Deacetylase (HDAC) inhibitor that can penetrate the blood-brain barrier (BBB). It is known to inhibit HDAC1 and HDAC3, and has shown efficacy in suppressing inflammatory responses and inhibiting cell proliferation in various studies.
- Inhibits HDAC1 (IC50: 198 nM) and HDAC3 (IC50: 157 nM)
- Penetrates the blood-brain barrier (BBB)
- Suppresses LPS-induced IL-1β production
- Decreases IL-6 secretion in PBMCs
- Inhibits JS-1 cell proliferation
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Medchemexpress LLC Guanfacine (hydrochloride) | 29110-48-3 | 99.98% | 282.55 | 25 MG
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Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist, highly selective for the α2A receptor subtype. It has effects in producing hypotension and sedation, and can be used for research on various prefrontal cortex (PFC) cognitive disorders, including Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).
- Orally active and blood-brain barrier permeable noradrenergic α2A agonist.
- High selectivity for the α2A receptor subtype.
- Increases delay-related neuronal firing needed for working memory on dIPFC neurons.
- Improves PFC cognitive function by inhibiting CAMP production, closing HCN channels, and strengthening PFC networks.
- Enhances PFC working memory function and improves impulse control in aged monkeys.
- Improves cognitive performance when infused directly into the rat or monkey PFC.
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eMolecules [4-Chloro-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.830 | C7H3BrClF3Zn | 0.000 | [Br-].FC(F)(F)c1cc(Cl)ccc1[Zn+] | 50ml | 812584967
[4-Chloro-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.830 | C7H3BrClF3Zn | 0.000 | [Br-].FC(F)(F)c1cc(Cl)ccc1[Zn+] | 50ml | 812584967
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Medchemexpress LLC 2-(3,5-difluoro-4-hydroxyanilino)-5,7-dimethyl-8-(3-methylbutyl)-7H-pteridin-6-one | 501437-28-1 | MFCD11223662 | 99.4% | 391.42 g·mol⁻1 | C19H23F2N5O2 | 100 MG
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BI-D1870 is an ATP-competitive, cell-permeable, brain-penetrant small-molecule inhibitor of p90 ribosomal S6 kinases (RSK1-4) with low-nanomolar potency. It is intended for research use in biochemical and cellular studies targeting RSK-mediated signaling.
- Inhibits RSK1-4 with reported IC50s of 31 nM, 24 nM, 18 nM, and 15 nM, respectively.
- ATP-competitive mechanism of action.
- Cell permeable and reported to be brain penetrant.
- High chemical purity suitable for research (reported ≥99%).
- Supplied as a solid and available as DMSO solutions for assays.
- Molecular formula C19H23F2N5O2; molecular weight 391.42 g·mol⁻1.
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eMolecules 7565-57-3 | Cyclohexylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671993 | 228.440 | C6H11BrZn | 0.000 | [Br-].[Zn+]C1CCCCC1 | 50ml | 532652728
Cyclohexylzinc bromide, 0.50 M in THF | Synthonix | 7565-57-3 | MFCD00671993 | 228.440 | C6H11BrZn | 0.000 | [Br-].[Zn+]C1CCCCC1 | 50ml | 532652728
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eMolecules 135-07-9 | Medchem Express | Methyclothiazide | 10mg | 527573895 | HY-B0562 | MFCD00242610 | 360.22 | C9H11Cl2N3O4S2
ChemScene | 2-(Propylamino)ethanol | 10g | 569146232 | CS-0105782 | 16369-21-4 | MFCD00002844 | 103.165 | C5H13NO
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eMolecules 27524-58-9 | [4-(Methoxymethoxy)phenyl]magnesium bromide, 0.50 M in THF | Synthonix241.367 | C8H9BrMgO2 | 0.000 | [Br-].COCOc1ccc([Mg+])cc1 | 25ml | 812262711
[4-(Methoxymethoxy)phenyl]magnesium bromide, 0.50 M in THF | Synthonix | 27524-58-9241.367 | C8H9BrMgO2 | 0.000 | [Br-].COCOc1ccc([Mg+])cc1 | 25ml | 812262711
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Medchemexpress LLC BI-9627 (hydrochloride) | 1422252-46-7 | 98.01% | 392.80 | 100 MG
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BI-9627 hydrochloride is a potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with IC50 values of 6 nM in intracellular pH recovery (pHi) and 31 nM in human platelet swelling assays. It exhibits over 30-fold selectivity against NHE2 and shows no measurable inhibitory activity against the NHE3 isoform. This compound demonstrates low DDI potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injury.
- Decreases autophagy in HTR-8/SVneo cells
- Significantly reduces the pHi of human sperm
- Partially reverses the effect of DMA
- Prolongs Ca2+ recovery time in KO hiPSC-CMs
- For research use only
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eMolecules 1013082-37-5 | Tributyl(3,5-dimethylphenyl)stannane | Synthonix - Stock395.218 | C20H36Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)c1cc(C)cc(C)c1 | 1g | 505099297
Tributyl(3,5-dimethylphenyl)stannane | Synthonix - Stock | 1013082-37-5395.218 | C20H36Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)c1cc(C)cc(C)c1 | 1g | 505099297
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