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Filtered Search Results
Medchemexpress LLC BI-882370 | 1392429-79-6 | MFCD31618072 | 99.2% | 569.67 | C28H33F2N7O2S | 5 MG
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BI-882370 is a potent, selective small-molecule pan-RAF kinase inhibitor that binds the ATP binding site in the DFG-out (inactive) conformation. It demonstrates sub-nanomolar to low-nanomolar inhibition of BRAF V600E, wild-type BRAF, and CRAF, and is supplied as a high-purity solid for preclinical research applications.
- Potent pan-RAF inhibition with sub-nanomolar to low-nanomolar potency.
- Binds the ATP site in the DFG-out inactive conformation.
- High purity solid suitable for in vitro and in vivo preclinical studies.
- Well-defined chemical identity with confirmed molecular formula and mass.
- Available in small research-scale packaging for dose response experiments.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed AMBEED
5000887494 18-DIHYDROXYNAPHTHALENE- 250MG
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![Medchemexpress LLC N-(3-(5-((1-Ethylpiperidin-4-yl)(methyl)amino)-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl)-... | 1392429-79-6 | MFCD31618072 | 99.2% | 569.67 | C28H33F2N7O2S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240830.png-250.jpg)
Medchemexpress LLC N-(3-(5-((1-Ethylpiperidin-4-yl)(methyl)amino)-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl)-... | 1392429-79-6 | MFCD31618072 | 99.2% | 569.67 | C28H33F2N7O2S | 50 MG
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BI-882370 is a selective pan-RAF kinase inhibitor research compound for preclinical kinase and cellular studies. It binds the ATP site of RAF kinases in the DFG-out conformation and exhibits sub-nanomolar biochemical potency against BRAFV600E, wild-type BRAF, and CRAF. Supplied as a high-purity solid, it is intended for in vitro and in vivo pharmacology and assay development.
- High purity solid suitable for assays and preclinical work.
- Sub-nanomolar biochemical potency against BRAFV600E, BRAF, and CRAF.
- Binds RAF kinases in the DFG-out (inactive) conformation.
- Available in multiple small pack sizes for research use.
- Provided with molecular and spectral identifiers for reference.
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![Medchemexpress LLC (S)-3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c]oxaborol-1(3H)-ol | 2131798-13-3 | MFCD31657361 | 100.0% | 293.94 g/mol | C10H14BCl2NO4 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240899.png-250.jpg)
Medchemexpress LLC (S)-3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c]oxaborol-1(3H)-ol | 2131798-13-3 | MFCD31657361 | 100.0% | 293.94 g/mol | C10H14BCl2NO4 | 1 ML
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Ganfeborole hydrochloride is a boron-containing small-molecule antitubercular agent that inhibits Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) with an IC50 of 0.2 μM. It is supplied as a high-purity research compound in solution or solid form for biochemical and microbiology studies.
- Inhibits M. tuberculosis LeuRS with an IC50 of 0.2 μM.
- High purity suitable for research applications.
- Supplied as a 10 mM solution in DMSO; solid formats available.
- Soluble in DMSO (≈67.5 mg/mL); ultrasonic agitation recommended.
- Store sealed and protected from moisture; long-term solution storage at -80°C.
- Molecular weight 293.94 g/mol; formula C10H14BCl2NO4.
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Medchemexpress LLC Colesevelam hydrochl 25mg | 182815-44-7 | 25MG
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Colesevelam (hydrochloride) is a bile acid sequestrant that bind bile acids in the gut Colesevelam (hydrochloride) inhibits bile acid reabsorption leading to increased bile acid synthesis and reduced cholesterol levels in patients with cholestatic pruritus and Crohn s disease
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Medchemexpress LLC Ganfeborole hydrochloride | 2131798-13-3 | MFCD31657361 | 100.0% | 293.94 | C10H14BCl2NO4 | 1 MG
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Ganfeborole hydrochloride is a small-molecule antitubercular agent that inhibits Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS). Supplied as an off-white to light-yellow solid, it is intended for research use in biochemical and cellular assays; reported IC50 against Mtb LeuRS is 0.2 μM. Store sealed and away from moisture; in solvent, store at -80°C for long-term stability.
- LeuRS inhibitor with reported IC50 0.2 μM.
- High purity suitable for biochemical assays.
- Off-white to light-yellow solid form, convenient for handling.
- Available in multiple small-scale quantities for research workflows.
- Storage guidance provided for solid and solution stability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![Medchemexpress LLC N-[3-[5-[(1-ethyl-4-piperidinyl)methylamino]-3-(5-pyrimidinyl)-1H-pyrrolo[3,2-b]pyridin-1-yl]-2,4-difluorophenyl]-1-propanesulf... | 1392429-79-6 | 99.2% | 569.67 g·mol⁻¹ | C28H33F2N7O2S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241545.png-250.jpg)
Medchemexpress LLC N-[3-[5-[(1-ethyl-4-piperidinyl)methylamino]-3-(5-pyrimidinyl)-1H-pyrrolo[3,2-b]pyridin-1-yl]-2,4-difluorophenyl]-1-propanesulf... | 1392429-79-6 | 99.2% | 569.67 g·mol⁻¹ | C28H33F2N7O2S | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-882370 is a potent, selective pan-RAF kinase inhibitor used in preclinical research to probe RAF/MEK/ERK signaling and to evaluate antitumor activity in BRAF-mutant and wild-type models. It binds the ATP site in the DFG-out (inactive) conformation and exhibits sub-nanomolar to low-nanomolar inhibition of BRAF V600E, wild-type BRAF, and CRAF, making it useful as a research tool for pathway modulation and efficacy studies.
- Potent RAF kinase inhibition with sub-nanomolar to low-nanomolar activity.
- Binds the ATP site in the DFG-out (inactive) conformation.
- Suitable for in vitro and in vivo preclinical studies.
- Supplied in solid and DMSO solution formats for assay flexibility.
- High reported purity appropriate for research applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Rilpivirine hydrochloride | 700361-47-3 | MFCD11046523 | 99.8% | 402.88 | C22H19ClN6 | 25 MG
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Rilpivirine hydrochloride is the hydrochloride salt of rilpivirine, a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor (NNRTI) supplied for research and analytical applications. The material is offered as solid or solution formats and is accompanied by a product datasheet and safety data sheet for laboratory use.
- High purity suitable for research applications.
- Available in multiple pack sizes, including 25 mg.
- Provided with a datasheet and safety data sheet.
- Molecular formula C22H19ClN6 and molecular weight 402.88.
- Intended for non-clinical research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Apoatropine hydrochloride | 5978-81-4 | MFCD10574677 | 99.6% | 307.82 g/mol | C17H22ClNO2 | 25 MG
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Apoatropine hydrochloride is the hydrochloride salt of apoatropine, a tropane alkaloid isolated from Atropa belladonna. It is provided for research use and is used in pharmacological and biochemical studies involving tropane alkaloids, receptor interactions, and analytical characterization.
- High purity (99.6%) for reliable analytical and experimental results.
- Molecular weight 307.82 g/mol for accurate formulation and calculations.
- Hydrochloride salt form improves solubility in polar solvents.
- Available in small milligram quantities suitable for research and reference use.
- Intended for research use only and not for diagnostic or therapeutic applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Naphthol AS-E | 92-78-4 | 98.0% | 297.74 | C17H12ClNO2 | 50 MG
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Naphthol AS-E is a small-molecule, cell-permeable inhibitor of the KIX-KID protein-protein interaction used in biochemical and cell-based research. It binds the KIX domain of CBP and blocks the KIX-KID interaction, making it useful for mechanistic studies of transcriptional regulation.
- Inhibits KIX-KID interaction with IC50 2.26 μM.
- Binds CBP KIX domain (Kd ~8.6 μM).
- High purity: 98.0%.
- Molecular weight: 297.74 Da.
- Soluble in DMSO (~41.67 mg/mL) for in vitro use.
- Storage: powder stable at -20°C (up to 3 years) and 4°C (up to 2 years).
- Available as a 50 MG solid for laboratory research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1) | 29110-48-3 | MFCD00798230 | 99.9% | 282.55 | 100MG
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Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist that exhibits high selectivity for the α2A receptor subtype. It has demonstrated effects in producing hypotension and sedation. This compound can be utilized for research into various prefrontal cortex (PFC) cognitive disorders, such as Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).
- Orally active
- Blood-brain barrier permeable
- Noradrenergic α2A agonist
- High selectivity for the α2A receptor subtype
- Produces hypotension and sedation
- Used for research into prefrontal cortex (PFC) cognitive disorders
- Potentially useful for Tourette's syndrome
- Potentially useful for attention deficit hyperactivity disorder (ADHD)
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Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 1 G
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Butenafine Hydrochloride is a synthetic benzylamine antifungal that inhibits the synthesis of sterols by inhibiting squalene epoxidase. It is effective against dermal fungal infections such as athlete's foot and ringworm. The drug offers excellent epidermal penetration and prolonged retention, providing residual therapeutic activity. It also possesses anti-inflammatory activity.
- Inhibits sterol synthesis
- Effective against dermal fungal infections
- Excellent epidermal penetration
- Prolonged retention time
- Possesses anti-inflammatory activity
- Safe and effective for tinea corporis cruris and tinea manuum pedis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Milveterol (hydrochloride) | 804518-03-4 | 98.2% | C25H30ClN3O4 | 100 MG
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Milveterol hydrochloride is a long-acting β2-adrenergic receptor agonist. It can be used in the study of asthma and chronic obstructive pulmonary disease (COPD).
- Long-acting β2-adrenergic receptor agonist
- Suitable for asthma research
- Suitable for chronic obstructive pulmonary disease (COPD) research
- Bronchodilator
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Medchemexpress LLC Thiobis-beta-Galactose-propyne | 1989627-40-8 | 25 MG
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The product is a reagent intended solely for testing and research purposes. It is not to be used as pharmaceuticals, food, or household goods. If used for purposes other than testing and research, no warranty is provided. For uses other than testing and research or as a raw material, inquiries should be directed to the sales department. For pharmaceutical raw materials, the product is sold to manufacturers as raw materials for dedicated pharmaceutical products and pharmaceutical additives. A confirmation document is required for the purchase of dedicated pharmaceutical products (those with "dedicated pharmaceutical" in the product name).
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AdipoGen 2-Propyl-2-pentenoic acid
Chemical. CAS 60218-41-9. Formula C8H14O2. MW 142.2. Synthetic A major beta-oxidation metabolite of valproic acid VPA. Exhibits anticonvulsive potency similar to VPA and may be at least partially responsible for its neurological activity. Compound can be used as analytical reference material.
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