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Filtered Search Results
Medchemexpress LLC Tolazoline hydrochloride | 59-97-2 | 99.93% | C10H13ClN2 | 1 G
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Tolazoline hydrochloride, also known as Imidaline hydrochloride, is an alpha-adrenergic receptor antagonist. It inhibits noradrenaline-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. This compound is utilized in research for conditions such as erectile dysfunction, alpha2-adrenergic receptor agonist-related poisoning, and skin vascular diseases.
- Inhibits noradrenaline-induced cell contraction
- Modulates vascular resistance
- Increases arterial pressure
- Reverses bradycardia and tachypnea
- Supports research on erectile dysfunction
- Supports research on alpha2-adrenergic receptor agonist-related poisoning
- Supports research on skin vascular diseases
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586636 VONOPRAZAN HYDROCHL 25MG
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Medchemexpress LLC KTX-582 | 2573298-13-0 | 98.7% | 872.93 | 1 MG
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KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. It can induce apoptosis in MYD88MT DLBCL and is efficient at inducing in vivo tumor regressions in a lymphoma model.
- Potent IRAK4 degrader
- Induces apoptosis in MYD88MT DLBCL
- Efficient at inducing in vivo tumor regressions in lymphoma models
- Degrades IRAK4 in whole blood monocyte and lymphocyte with IC50s of <0.05 μM
- Inhibits IRAK4 in human whole blood LPS TNFα with an IC50 of 0.05-1 μM
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Selleck Chemical LLC BI-7273
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BI-7273 is a potent selective and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay
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Selleck Chemical LLC BI-4464
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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM
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Aobchem AOBCHEM
5000862538 5-BROMO-2- 2-PROPEN-1-YLOXY BE
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Aobchem AOBCHEM
5000862542 N-METHOXY-N-METHYL-1-NAPHTHALE
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Ambeed AMBEED
5000868115 8-BROMO-1234-TETRAHYDROISO 1GR
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eMolecules 21926-00-1 | 4-Aminotetrahydro-2H-thiopyran | Apollo Scientific | MFCD07371524 | 117.210 | C5H11NS | 98.000 | NC1CCSCC1 | 1g | 600855493
4-Aminotetrahydro-2H-thiopyran | Apollo Scientific | 21926-00-1 | MFCD07371524 | 117.210 | C5H11NS | 98.000 | NC1CCSCC1 | 1g | 600855493
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Medchemexpress LLC SOCE inhibitor 1 | 2169316-15-6 | 99.7% | 513.47 | 50 MG
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SOCE inhibitor 1, also known as Compound 39, is a potent store-operated calcium entry (SOCE) inhibitor. It demonstrates good stability in plasma and an IC50 of 4.4 μM, making it suitable for various research applications.
- Potent store-operated calcium entry (SOCE) inhibitor
- IC50 of 4.4 μM
- Good stability in plasma
- White to pink solid appearance
- Purity of 99.73%
- For research use only
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Selleck Chemical LLC CB-5339-5mg
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CB-5339 is a potent p97/Valosin Containing Protein (VCP) inhibitor with an IC50 of 9 nM.
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Medchemexpress LLC BI-9564 | 1883429-22-8 | MFCD09930810 | 98.7% | 353.41 | 5 MG
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BI-9564 is a potent, selective, and cell-permeable BRD9/BRD7 bromodomains inhibitor.
- Potent, selective, and cell-permeable BRD9/BRD7 bromodomains inhibitor.
- IC₅₀ of 75 nM for BRD9 and 3.4 μM for BRD7.
- Kds of 14 nM for BRD9 and 239 nM for BRD7.
- Highly selective, with an IC₅₀ > 100 μM for BET family.
- Shows no activity against 324 kinases (<5 μM).
- Antiproliferative effect on human acute myeloid eosinophilic leukemia cell line EOL-1 (EC₅₀ 800 nM).
- More than 10-fold selective for BRD9 over the highly homologous bromodomain BRD7.
- Attractive ADME/PK profiles for in vivo proof-of-concept studies.
- Results in additional survival benefit in a xenograft model of human AML.
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Medchemexpress LLC NORTROPINE HYDROCHL 1G
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5000210700 NORTROPINE HYDROCHL 1G
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Ambeed AMBEED
5000866787 1234-TETRAHYDRO-15-NAPHTHY 1GR
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eMolecules 4707-33-9 | Medchem Express | -Lapachone | 5mg | 736631266 | HY-N2848 | MFCD00022287 | 242.274 | C15H14O3
Ambeed | Methyl (S)-26-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-14-dihydropyridine-3-carboxylate | 10mg | 525166031 | A273444 | 98625-26-4 | MFCD00153769 | 356.301 | C16H15F3N2O4
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