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Filtered Search Results
Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M, and primary mutant EGFR del19 (IC50=1 nM). It also shows activity against EGFR wt (IC50=190 nM). This product demonstrates high kinome selectivity and good DMPK properties and is for research use only.
- Fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor
- Inhibits triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM)
- Inhibits double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM)
- Shows activity against EGFR wt (IC50=190 nM)
- Demonstrates high kinome selectivity and good DMPK properties
- Leads to tumor regressions in human PC-9 triple mutant NSCLC xenograft model in mice
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eMolecules 312693-11-1 | 1-Ethylpentylzinc bromide, 0.50 M in THF | Synthonix244.480 | C7H15BrZn | 0.000 | [Br-].CCCCC([Zn+])CC | 100ml | 532652800
1-Ethylpentylzinc bromide, 0.50 M in THF | Synthonix | 312693-11-1244.480 | C7H15BrZn | 0.000 | [Br-].CCCCC([Zn+])CC | 100ml | 532652800
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 17217-57-1 | MeO-bpy | ChemScene | MFCD00233880 | 216.240 | C12H12N2O2 | 98.000 | COc1ccnc(c1)-c1cc(OC)ccn1 | 5g | 572231378
MeO-bpy | ChemScene | 17217-57-1 | MFCD00233880 | 216.240 | C12H12N2O2 | 98.000 | COc1ccnc(c1)-c1cc(OC)ccn1 | 5g | 572231378
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 62890-98-6 | 2,5-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311475 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc(OC)c([Mg+])c1 | 50ml | 437237129
2,5-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 62890-98-6 | MFCD01311475 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc(OC)c([Mg+])c1 | 50ml | 437237129
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eMolecules (2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
(2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
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eMolecules Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
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eMolecules 204324-71-0 | (3,5-Ditert-butylphenyl)magnesium bromide, 0.5 M in THF | Synthonix293.531 | C14H21BrMg | 0.000 | [Br-].CC(C)(C)c1cc([Mg+])cc(c1)C(C)(C)C | 50ml | 812584972
(3,5-Ditert-butylphenyl)magnesium bromide, 0.5 M in THF | Synthonix | 204324-71-0293.531 | C14H21BrMg | 0.000 | [Br-].CC(C)(C)c1cc([Mg+])cc(c1)C(C)(C)C | 50ml | 812584972
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules [3-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)propyl]zinc bromide, 0.50 M in THF | Synthonix |345.740 | C9H22BrNSi2Zn | 0.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Zn+] | 100ml | 794559329
[3-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)propyl]zinc bromide, 0.50 M in THF | Synthonix |345.740 | C9H22BrNSi2Zn | 0.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Zn+] | 100ml | 794559329
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1135389-59-1 | (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.50 M in THF | Synthonix | MFCD07698709 | 232.380 | C4H7BrO2Zn | 0.000 | [Br-].[Zn+]CC1OCCO1 | 50ml | 532652736
(1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.50 M in THF | Synthonix | 1135389-59-1 | MFCD07698709 | 232.380 | C4H7BrO2Zn | 0.000 | [Br-].[Zn+]CC1OCCO1 | 50ml | 532652736
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 932-31-0 | 2-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00010350 | 195.342 | C7H7BrMg | 0.000 | [Br-].Cc1ccccc1[Mg+] | 100ml | 437237317
2-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 932-31-0 | MFCD00010350 | 195.342 | C7H7BrMg | 0.000 | [Br-].Cc1ccccc1[Mg+] | 100ml | 437237317
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 254454-47-2 | 4-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311444 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccc([Zn+])cc1 | 100ml | 532652919
4-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | 254454-47-2 | MFCD01311444 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccc([Zn+])cc1 | 100ml | 532652919
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 307531-97-1 | 2,3-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260173 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1cccc([Zn+])c1Cl | 100ml | 532652741
2,3-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | 307531-97-1 | MFCD02260173 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1cccc([Zn+])c1Cl | 100ml | 532652741
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1142218-21-0 | 4-tert-Butoxy-4-oxobutylzinc bromide, 0.50 M in THF | Synthonix288.490 | C8H15BrO2Zn | 0.000 | [Br-].CC(C)(C)OC(=O)CCC[Zn+] | 100ml | 532652643
4-tert-Butoxy-4-oxobutylzinc bromide, 0.50 M in THF | Synthonix | 1142218-21-0288.490 | C8H15BrO2Zn | 0.000 | [Br-].CC(C)(C)OC(=O)CCC[Zn+] | 100ml | 532652643
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 193819-99-7 | 3-Methoxy-3-oxopropylzinc bromide, 0.50 M in THF | Synthonix232.380 | C4H7BrO2Zn | 0.000 | [Br-].COC(=O)CC[Zn+] | 25ml | 627353695
3-Methoxy-3-oxopropylzinc bromide, 0.50 M in THF | Synthonix | 193819-99-7232.380 | C4H7BrO2Zn | 0.000 | [Br-].COC(=O)CC[Zn+] | 25ml | 627353695
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 109669-45-6 | Tributyl(5,6-dihydro-4H-pyran-2-yl)stannane | Synthonix - Stock373.168 | C17H34OSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C1=CCCCO1 | 1g | 525924750
Tributyl(5,6-dihydro-4H-pyran-2-yl)stannane | Synthonix - Stock | 109669-45-6373.168 | C17H34OSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C1=CCCCO1 | 1g | 525924750
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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