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Filtered Search Results
Medchemexpress LLC BI-0474 | 2750570-55-7 | 99.8% | 587.74 | 50 MG
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BI-0474 is a potent KRASG12C inhibitor that demonstrates an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. It exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation and shows good anti-tumour activity in non-small cell lung cancer xenograft models. Designed by Boehringer Ingelheim, this compound is available for research use only.
- Potent KRASG12C inhibitor
- IC50 value of 7.0 nM for GDP-KRAS::SOS1 protein-protein interaction
- Demonstrates anti-proliferative activity against NCI-H358 cells with G12C mutation
- Shows anti-tumour activity in non-small cell lung cancer xenograft models
- For research use only
- Purity of 99.83%
- Molecular weight of 587.74
- Chemical formula is C30H37N9O2S
- Appears as a white to off-white solid
- Target: KRAS-SOS1
- EC50 = 26 nM on NCI-H358 cells (G12C mutant)
- Soluble in DMSO at 100 mg/mL
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eMolecules (4-Cyano-3,5-difluorophenyl)zinc bromide, 0.5 M in THF | Synthonix |283.380 | C7H2BrF2NZn | 0.000 | [Br-].Fc1cc([Zn+])cc(F)c1C#N | 25ml | 812584956
(4-Cyano-3,5-difluorophenyl)zinc bromide, 0.5 M in THF | Synthonix |283.380 | C7H2BrF2NZn | 0.000 | [Br-].Fc1cc([Zn+])cc(F)c1C#N | 25ml | 812584956
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Aobchem 2-Bromo-1-naphthalenol | ≥97% | CAS 771-15-3 | C10H7BrO | 25g
2-Bromo-1-naphthalenol | ≥97% | CAS 771-15-3 | C10H7BrO | 25g
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eMolecules Target Molecule Pemigatinib 25mg 574599730 T12401 1513857-77-6 [null] 487.508 C24H27F2N5O4
Target Molecule Pemigatinib 25mg 574599730 T12401 1513857-77-6 [null] 487.508 C24H27F2N5O4
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eMolecules 307496-33-9 | 2,6-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(F)c1C[Zn+] | 50ml | 532652762
2,6-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | 307496-33-9272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(F)c1C[Zn+] | 50ml | 532652762
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eMolecules 1395895-19-8 | 3-Fluoro-5-methoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD11553258 | 229.331 | C7H6BrFMgO | 0.000 | [Br-].COc1cc(F)cc([Mg+])c1 | 50ml | 437237244
3-Fluoro-5-methoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 1395895-19-8 | MFCD11553258 | 229.331 | C7H6BrFMgO | 0.000 | [Br-].COc1cc(F)cc([Mg+])c1 | 50ml | 437237244
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Medchemexpress LLC Clobutinol (hydrochloride) | 1215-83-4 | 99.9% | 292.25 | 1 ML
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Clobutinol hydrochloride is a compound with anti-tussive effects. It affects heart rate and blood pressure and can be used for cough-related research.
- Anti-tussive effects
- Affects heart rate and blood pressure
- Used for cough-related research
- 99.9% purity
- Molecular weight: 292.25
- CAS Number: 1215-83-4
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
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eMolecules 22873-28-5 | 4-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311467 | 209.369 | C8H9BrMg | 0.000 | [Br-].CCc1ccc([Mg+])cc1 | 50ml | 437237188
4-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 22873-28-5 | MFCD01311467 | 209.369 | C8H9BrMg | 0.000 | [Br-].CCc1ccc([Mg+])cc1 | 50ml | 437237188
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eMolecules 1447963-71-4 | Ambeed | 2-Diphenylphosphino-26-bis(dimethylamino)-11-biphenyl | 100mg | 573012658 | A968407 | MFCD29059466 | 424.528 | C28H29N2P
Ambeed | (2R3R4S5R6S)-2-(Acetoxymethyl)-6-mercaptotetrahydro-2H-pyran-345-triyl triacetate | 250mg | 525198766 | A371264 | 19879-84-6 | 364.370 | C14H20O9S
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eMolecules 1115492-92-6 | 2-Methyl-4-pyridylzinc bromide, 0.25 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cc([Zn+])ccn1 | 50ml | 532652892
2-Methyl-4-pyridylzinc bromide, 0.25 M in THF | Synthonix | 1115492-92-6237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cc([Zn+])ccn1 | 50ml | 532652892
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eMolecules 352530-31-5 | 3-Iodobenzylzinc bromide, 0.50 M in THF | Synthonix | MFCD02260139 | 362.310 | C7H6BrIZn | 0.000 | [Br-].[Zn+]Cc1cccc(I)c1 | 50ml | 532652873
3-Iodobenzylzinc bromide, 0.50 M in THF | Synthonix | 352530-31-5 | MFCD02260139 | 362.310 | C7H6BrIZn | 0.000 | [Br-].[Zn+]Cc1cccc(I)c1 | 50ml | 532652873
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eMolecules 135579-86-1 | (Cyclohexylmethyl)zinc bromide, 0.50 M in THF | Synthonix242.470 | C7H13BrZn | 0.000 | [Br-].[Zn+]CC1CCCCC1 | 25ml | 627353542
(Cyclohexylmethyl)zinc bromide, 0.50 M in THF | Synthonix | 135579-86-1242.470 | C7H13BrZn | 0.000 | [Br-].[Zn+]CC1CCCCC1 | 25ml | 627353542
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eMolecules 138084-62-5 | [3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propyl]magnesium bromide, 0.5M in THF | Synthonix304.661 | C9H22BrMgNSi2 | 95.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Mg+] | 100ml | 794559326
[3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propyl]magnesium bromide, 0.5M in THF | Synthonix | 138084-62-5304.661 | C9H22BrMgNSi2 | 95.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Mg+] | 100ml | 794559326
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Medchemexpress LLC NNC-711 hydrochloride | 145645-62-1 | MFCD00153853 | 99.8% | 386.87 g/mol | C21H23ClN2O3 | 1 ML
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NNC-711 (NO-711 hydrochloride) is a potent, selective inhibitor of the GABA transporter GAT-1 used in neuroscience research to modulate GABA uptake. It is supplied as a high-purity solid and as a 10 mM solution for laboratory use.
- Potent and selective GAT-1 inhibitor.
- High purity (≈99.8%).
- Available as solid powder and 10 mM solution.
- Molecular weight 386.87 g/mol; formula C21H23ClN2O3.
- Suitable for electrophysiology, GABA uptake assays, and in vivo pharmacology.
- Provided in research-scale quantities (mg ranges and 1 mL solution).
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eMolecules 1610475-27-8 | 4-Chloro-2,6-dimethylphenylmagnesium bromide, 0.50 M in THF | Synthonix243.810 | C8H8BrClMg | 95.000 | [Br-].Cc1cc(Cl)cc(C)c1[Mg+] | 100ml | 649431011
4-Chloro-2,6-dimethylphenylmagnesium bromide, 0.50 M in THF | Synthonix | 1610475-27-8243.810 | C8H8BrClMg | 95.000 | [Br-].Cc1cc(Cl)cc(C)c1[Mg+] | 100ml | 649431011
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