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Filtered Search Results
Medchemexpress LLC Pifusertib hydrochloride | 2930090-28-9 | 99.9% | 460.96 | 1 ML
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Pifusertib hydrochloride is a potent, selective, orally active allosteric Akt inhibitor that triggers anti-myeloma activities. It enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition, leading to apoptosis and autophagy.
- Potent, selective, orally active allosteric Akt inhibitor.
- Triggers anti-myeloma activities.
- Enhances fatal endoplasmic reticulum (ER) stress.
- Induces apoptosis and autophagy.
- Blocks basal phosphorylation of Akt and downstream targets in MM cells.
- Induces cytotoxicity in MM cells with high baseline Akt phosphorylation.
- Inhibits tumor growth in murine xenograft models.
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Medchemexpress LLC Stachydrine hydrochloride | 4136-37-2 | 179.64 | 500 MG
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Stachydrine hydrochloride is the major active constituent of *Leonurus artemisia*, a potential therapy for cardiovascular diseases. It can inhibit the NF-κB signal pathway, exhibiting anti-hypertrophic activities.
- Major active constituent of *Leonurus artemisia*
- Potential therapy for cardiovascular diseases
- Inhibits the NF-κB signal pathway
- Exhibits anti-hypertrophic activities
- Suppresses p-IκB (ser32) protein in cytosol
- Suppresses NF-κB (p65) protein in nucleus
- Inhibits MCF-7 and T47D cell proliferation in a dose- and time-dependent manner
- Increases frequency of MCF-7 and T47D cells at G1 phase of cell cycle, suggesting cell cycle arrest
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eMolecules 1142219-89-3 | 4-Bromo-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix362.310 | C7H6BrIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1Br | 50ml | 532652628
4-Bromo-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | 1142219-89-3362.310 | C7H6BrIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1Br | 50ml | 532652628
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eMolecules 100073-15-2 | 2-(Tributylstannyl)propene | Synthonix - Stock | MFCD10699166 | 331.131 | C15H32Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)C(C)=C | 10g | 525923960
2-(Tributylstannyl)propene | Synthonix - Stock | 100073-15-2 | MFCD10699166 | 331.131 | C15H32Sn | 0.000 | CCCC[Sn](CCCC)(CCCC)C(C)=C | 10g | 525923960
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eMolecules 611168-63-9 | 5-Chloro-2-(tributylstannyl)pyridine | Synthonix - Stock | MFCD10699156 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)cn1 | 5g | 525913207
5-Chloro-2-(tributylstannyl)pyridine | Synthonix - Stock | 611168-63-9 | MFCD10699156 | 402.590 | C17H30ClNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)cn1 | 5g | 525913207
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TARGETMOL CHEMICALS INC VRT-532 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB) which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate. purity: 99%
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Medchemexpress LLC (+)-Camphor-10-sulfonic acid | 3144-16-9 | MFCD00064157 | 98.0% | 232.30 | C10H16O4S | 100g
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( )-Camphor-10-sulfonic acid (( )-10-Camphorsulfonic acid) is an effective pancreatic lipase (PL) inhibitor ( )-Camphor-10-sulfonic acid is promising for research of obesity[1]
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Ambeed AMBEED
5000950258 5-BROMO-1234-TETRAHYDRON 100MG
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eMolecules 4294-57-9 | 4-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00000040 | 195.342 | C7H7BrMg | 98.000 | [Br-].Cc1ccc([Mg+])cc1 | 100ml | 437237323
4-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 4294-57-9 | MFCD00000040 | 195.342 | C7H7BrMg | 98.000 | [Br-].Cc1ccc([Mg+])cc1 | 100ml | 437237323
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AdipoGen Tributylmethylammonium Cl
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Chemical. CAS 56375-79-2. Formula C13H30ClN. MW 235.84. Tributylmethylammonium chloride TBMAC is a quaternary ammonium salt used in various chemical and biochemical applications. It consists of a tetrabutylammonium cation Bu3N and a chloride anion Cl-, with a methyl group CH3 attached to the nitrogen atom of the ammonium cation. TBMAC is commonly used as a phase-transfer catalyst PTC in organic synthesis. Phase-transfer catalysis involves the transfer of reactants from one phase usually an aqueous phase to another phase usually an organic phase to facilitate a chemical reaction. TBMAC helps in the transfer of ions or molecules between these phases, allowing reactions that might not occur under standard conditions. Some common applications of TBMAC include, nucleophilic substitution reactions, halogenation reactions or alkylation and acylation reactions.
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Medchemexpress LLC MK-571 sodium | 115103-85-0 | MFCD00878420 | 99.8% | 537.07 | C26H26ClN2NaO3S2 | 10 MG
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MK-571 sodium is a research-grade small molecule inhibitor that functions as a potent leukotriene D4 (LTD4) receptor antagonist and an inhibitor of multidrug resistance-associated proteins. Supplied as a high-purity solid for in vitro and in vivo studies, it is commonly used to probe leukotriene signaling and transporter-mediated processes in pharmacology research.
- Potent leukotriene D4 receptor antagonist with low nanomolar affinity.
- Inhibits multidrug resistance-associated proteins (MRP4/ABCC4 and ABCC1).
- High purity solid suitable for analytical and biological assays.
- Soluble in DMSO and formulatable for in vivo dosing.
- Stable under recommended storage conditions for research use.
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eMolecules Synthonix - Stock (1-tert-Butoxycarbonylpyrrolidin-3-yl)methylzinc iodide 0.5M in THF 50ml 353003197 B31635 2135683-48-4 MFCD31536790 376.540 C10H18INO2Zn
Synthonix - Stock (1-tert-Butoxycarbonylpyrrolidin-3-yl)methylzinc iodide 0.5M in THF 50ml 353003197 B31635 2135683-48-4 MFCD31536790 376.540 C10H18INO2Zn
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eMolecules 737797-48-7 | 4-tert-Butylbenzylzinc bromide, 0.50 M in THF | Synthonix292.530 | C11H15BrZn | 0.000 | [Br-].CC(C)(C)c1ccc(C[Zn+])cc1 | 25ml | 627353508
4-tert-Butylbenzylzinc bromide, 0.50 M in THF | Synthonix | 737797-48-7292.530 | C11H15BrZn | 0.000 | [Br-].CC(C)(C)c1ccc(C[Zn+])cc1 | 25ml | 627353508
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eMolecules 127349-68-2 | 4-tert-Butylbenzylmagnesium bromide, 0.25 M in 2-MeTHF | Synthonix - Stock251.450 | C11H15BrMg | 0.000 | [Br-].CC(C)(C)c1ccc(C[Mg+])cc1 | 100ml | 507876233
4-tert-Butylbenzylmagnesium bromide, 0.25 M in 2-MeTHF | Synthonix - Stock | 127349-68-2251.450 | C11H15BrMg | 0.000 | [Br-].CC(C)(C)c1ccc(C[Mg+])cc1 | 100ml | 507876233
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eMolecules 521917-51-1 | 1,2-Dihydro-naphthalene-3-boronic acid | J & W PharmLab LLC | MFCD11506070 | 174.010 | C10H11BO2 | 96.000 | OB(O)C1=Cc2ccccc2CC1 | 5g | 289351635
1,2-Dihydro-naphthalene-3-boronic acid | J & W PharmLab LLC | 521917-51-1 | MFCD11506070 | 174.010 | C10H11BO2 | 96.000 | OB(O)C1=Cc2ccccc2CC1 | 5g | 289351635
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