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Filtered Search Results
Medchemexpress LLC 1-(2-(((diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride | 145645-62-1 | MFCD00153853 | 99.8% | 386.87 g/mol | C21H23ClN2O3 | 25 MG
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NNC-711 (NO-711 hydrochloride) is a potent and selective inhibitor of the GABA transporter GAT-1 supplied as a high-purity solid for research applications in neuroscience and pharmacology. It exhibits anticonvulsant and analgesic activity in vivo and is used to study GABA uptake and transporter function.
- Potent and selective GAT-1 inhibitor; IC50 ≈ 0.04 μM for human GAT-1.
- High purity suitable for in vitro and in vivo research.
- White to off-white solid, supplied in small pack sizes for laboratory use.
- Stable when stored sealed at low temperature, away from moisture.
- For research use only; not for human or clinical applications.
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eMolecules 186000-43-1 | 4-(Methoxycarbonyl)phenylzinc iodide, 0.50 M in THF | Synthonix327.430 | C8H7IO2Zn | 0.000 | [I-].COC(=O)c1ccc([Zn+])cc1 | 50ml | 532652914
4-(Methoxycarbonyl)phenylzinc iodide, 0.50 M in THF | Synthonix | 186000-43-1327.430 | C8H7IO2Zn | 0.000 | [I-].COC(=O)c1ccc([Zn+])cc1 | 50ml | 532652914
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eMolecules 126979-68-8 | 1-Ethylpentylmagnesium bromide, 0.25 M in THF | Synthonix - Stock | MFCD02260223 | 203.406 | C7H15BrMg | 0.000 | [Br-].CCCCC([Mg+])CC | 500ml | 437237178
1-Ethylpentylmagnesium bromide, 0.25 M in THF | Synthonix - Stock | 126979-68-8 | MFCD02260223 | 203.406 | C7H15BrMg | 0.000 | [Br-].CCCCC([Mg+])CC | 500ml | 437237178
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eMolecules 194366-72-8 | 1-Ethoxyvinylzinc chloride, 0.25M in THF/Pentane | Synthonix - Stock171.930 | C4H7ClOZn | 95.000 | [Cl-].CCOC([Zn+])=C | 100ml | 363363217
1-Ethoxyvinylzinc chloride, 0.25M in THF/Pentane | Synthonix - Stock | 194366-72-8171.930 | C4H7ClOZn | 95.000 | [Cl-].CCOC([Zn+])=C | 100ml | 363363217
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AdipoGen Naphthol AS phosphate
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Chemical. CAS 13989-98-5. Formula C17H14NO5P. MW BD9837. Naphthol AS phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS phosphate is converted to naphthol AS displaying excitation/emission spectra of 388/516nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting, dot blot applications and in situ PCR.
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Medchemexpress LLC Siramesine hydrochloride | 224177-60-0 | 99.7% | C30H32ClFN2O | 2 MG
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Siramesine hydrochloride, also known as Lu 28-179 hydrochloride, is a potent sigma-2 receptor agonist. It demonstrates high selectivity for sigma-2 receptors over sigma-1 receptors. This compound triggers cell death by destabilizing mitochondria and exhibits anti-cancer activity.
- Potent sigma-2 receptor agonist
- High selectivity for sigma-2 receptors
- Triggers cell death via mitochondrial destabilization
- Shows anti-cancer activity
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eMolecules 131379-40-3 | 2-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | MFCD01863743 | 294.450 | C9H9BrO2Zn | 0.000 | [Br-].CCOC(=O)c1ccccc1[Zn+] | 50ml | 532652803
2-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | 131379-40-3 | MFCD01863743 | 294.450 | C9H9BrO2Zn | 0.000 | [Br-].CCOC(=O)c1ccccc1[Zn+] | 50ml | 532652803
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Medchemexpress LLC Selegiline hydrochloride | 14611-52-0 | MFCD00069299 | 99.94% | C13H18ClN | 1 ML
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Selegiline hydrochloride (Deprenyl hydrochloride) is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. It exhibits 450-fold selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline hydrochloride can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder.
- Potent, selective, and irreversible inhibitor of MAO-B
- Exhibits 450-fold selectivity for MAO-B over MAO-A
- Increases efflux of norepinephrine, dopamine, and serotonin from rat hypothalamus
- Inhibits efflux of dihydroxyphenylacetic acid and 5-hydroxyindoleacetic acid
- Reduces cocaine self-administration in mice
- Reduces DOPAC and 5-HIAA concentrations in the frontal cortex
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Medchemexpress LLC Selegiline hydrochloride | 14611-52-0 | 99.96% | C13H18ClN | 100 MG
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Selegiline hydrochloride (Deprenyl) is a potent, selective, and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. It exhibits 450-fold selectivity for MAO-B over MAO-A (IC50=23 μM). This compound is used in research for Parkinson's disease, Alzheimer's disease, and major depressive disorder.
- Potent, selective, irreversible MAO-B inhibitor.
- IC50 of 51 nM for MAO-B.
- 450-fold selectivity for MAO-B over MAO-A.
- Research applications: Parkinson's, Alzheimer's, major depressive disorder.
- Inhibits recombinant human MAO-B.
- Increases efflux of NE, DA, and 5-HT from rat hypothalamus in vitro.
- Reduces cocaine self-administration in mice.
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Medchemexpress LLC BI-0474 | 2750570-55-7 | 99.8% | 587.74 | 50 MG
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BI-0474 is a potent KRASG12C inhibitor that demonstrates an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. It exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation and shows good anti-tumour activity in non-small cell lung cancer xenograft models. Designed by Boehringer Ingelheim, this compound is available for research use only.
- Potent KRASG12C inhibitor
- IC50 value of 7.0 nM for GDP-KRAS::SOS1 protein-protein interaction
- Demonstrates anti-proliferative activity against NCI-H358 cells with G12C mutation
- Shows anti-tumour activity in non-small cell lung cancer xenograft models
- For research use only
- Purity of 99.83%
- Molecular weight of 587.74
- Chemical formula is C30H37N9O2S
- Appears as a white to off-white solid
- Target: KRAS-SOS1
- EC50 = 26 nM on NCI-H358 cells (G12C mutant)
- Soluble in DMSO at 100 mg/mL
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eMolecules 849619-05-2 | (3-(trifluoromethyl)pyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix291.380 | C6H3BrF3NZn | 0.000 | [Br-].FC(F)(F)c1cccnc1[Zn+] | 100ml | 532652977
(3-(trifluoromethyl)pyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix | 849619-05-2291.380 | C6H3BrF3NZn | 0.000 | [Br-].FC(F)(F)c1cccnc1[Zn+] | 100ml | 532652977
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Medchemexpress LLC Clobutinol (hydrochloride) | 1215-83-4 | 99.9% | 292.25 | 1 ML
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Clobutinol hydrochloride is a compound with anti-tussive effects. It affects heart rate and blood pressure and can be used for cough-related research.
- Anti-tussive effects
- Affects heart rate and blood pressure
- Used for cough-related research
- 99.9% purity
- Molecular weight: 292.25
- CAS Number: 1215-83-4
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
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eMolecules 64491-70-9 | (R)-Methyl glycidyl ether | Ochem Incorporation | MFCD00273372 | 88.106 | C4H8O2 | 98.000 | COC[C@H]1CO1 | 5g | 773146136
(R)-Methyl glycidyl ether | Ochem Incorporation | 64491-70-9 | MFCD00273372 | 88.106 | C4H8O2 | 98.000 | COC[C@H]1CO1 | 5g | 773146136
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eMolecules 873-77-8 | 4-Chlorophenylmagnesium bromide, 1.0 M in THF | Synthonix - Stock | MFCD00009926 | 215.760 | C6H4BrClMg | 0.000 | [Br-].[Mg+]c1ccc(Cl)cc1 | 100ml | 437237036
4-Chlorophenylmagnesium bromide, 1.0 M in THF | Synthonix - Stock | 873-77-8 | MFCD00009926 | 215.760 | C6H4BrClMg | 0.000 | [Br-].[Mg+]c1ccc(Cl)cc1 | 100ml | 437237036
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eMolecules 223418-75-5 | 2-Methyl-5-(tributylstannyl)thiazole | Synthonix - Stock | MFCD01319032 | 388.200 | C16H31NSSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(C)s1 | 500mg | 525921492
2-Methyl-5-(tributylstannyl)thiazole | Synthonix - Stock | 223418-75-5 | MFCD01319032 | 388.200 | C16H31NSSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(C)s1 | 500mg | 525921492
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