Acrylic acids and derivatives
eMolecules 179528-45-1 | Medchem Express | PD150606 | 5mg | 446255688 | HY-100529 | MFCD00949076 | 306.12 | C9H7IO2S
ChemScene | Methyl 3-oxotetrahydrothiophene-2-carboxylate | 1g | 572240057 | CS-W014330 | 2689-69-2 | MFCD00156156 | 160.190 | C6H8O3S
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Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | >99.91% | 649.70 | 50 MG
Vicriviroc maleate is a potent, selective, oral bioavailable, and central nervous system (CNS) penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in peripheral blood mononuclear cells (PBMC).
- Potent and selective CCR5 antagonist.
- Oral bioavailable and CNS penetrated.
- Inhibits HIV-1 in PBMC cells.
- Shows mean IC50 of 0.45 nM and IC90 of 4 nM for a panel of HIV isolates.
- Exhibits weak activity against hERG (IC50, 5.8 μM).
- Inhibits chemotactic response to MIP-1α with IC50 values below 1 nM.
- Suppresses RANTES-induced signaling with a mean IC50 of 4.2 ± 1.3 nM.
- Potently suppresses tested viral isolates with geometric mean EC50s of 0.04-2.3 nM and IC90s of 0.45-18 nM.
- Demonstrates good oral availability in rats and monkeys, with no acute CNS or GI effects at 10 mg/kg dose.
Medchemexpress LLC 7-O-Ethylmorroniside | 945721-10-8 | 5 MG
7-O-Ethylmorroniside is an iridoid glucoside isolated from the fruit of *Cornus officinalis*, which is traditionally used in Chinese medicine. This compound is primarily researched for its potential in treating kidney diseases, including diabetic nephropathy.
- Iridoid glucoside
- Isolated from the fruit of *Cornus officinalis*
- High purity of 99.91% (HPLC)
- Researched for kidney diseases, including diabetic nephropathy
Medchemexpress LLC 3-Bromopyridin-2-ol | 13466-43-8 | 174.00 | 5 G
3-Bromopyridin-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- For research use only
- Can be used as a biological material or organic compound for life science related research
- Listed under biochemical assay reagents
Medchemexpress LLC 3-amino-6-bromopyridine | 13534-97-9 | MFCD01646116 | 99.1% | 173.01 g/mol | C5H5BrN2 | 25 G
6-Bromopyridin-3-amine is an organic building block and research reagent used in medicinal chemistry and synthetic organic chemistry. Supplied as a high-purity solid, it serves as an intermediate for the preparation of brominated heterocycles and related derivatives, with documentation available for batch quality and safety.
- High reported purity (~99.1%).
- Molecular weight 173.01 g/mol.
- Chemical formula C5H5BrN2.
- Available in multiple lab-scale pack sizes for flexibility.
- Certificate of analysis and safety data sheet available.
Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 50 MG
Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor that can abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. It has potential for research into Alzheimer's disease and congenital muscular dystrophy (CMD). Omigapil maleate also functions as an apoptosis inhibitor and a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
- Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
- Potential research area: Alzheimer's disease.
- Acts as an apoptosis inhibitor.
- Can be used for research on congenital muscular dystrophy (CMD).
- Click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
Medchemexpress LLC 2-(Acetylamino)-2-deoxy-β-D-glucopyranosylamine | 4229-38-3 | MFCD00057751 | 98.4% | 220.22 g/mol | C8H16N2O5 | 1 MG
2-(Acetylamino)-2-deoxy-β-D-glucopyranosylamine is a carbohydrate-derived research reagent used in glycobiology and carbohydrate chemistry. Supplied as a purified solid (purity ≈98.4%), it is intended for use in glycan synthesis, enzymatic assays, and studies of protein-glycan recognition in basic research and biotechnology applications.
- High purity suitable for analytical and preparative work.
- Useful in glycan synthesis and modification studies.
- Suitable for enzymatic assays involving glycosyltransferases and glycosidases.
- Small molecular weight facilitates characterization by mass spectrometry and NMR.
- Available in small research quantities for laboratory workflows.
Medchemexpress LLC MAX-40279 hemifumarate | 2388506-43-0 | 99.6% | C22H23FN6OS·1/2C4H4O4 | 10MG
MAX-40279 hemifumarate is a small-molecule research inhibitor that targets FLT3 and FGFR kinases. It is orally active and retains activity against clinically relevant FLT3 mutants (for example, D835Y), making it suitable for studies of kinase inhibitor resistance and acute myelogenous leukemia (AML) signaling. It also inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT).
- Dual FLT3 and FGFR kinase inhibition
- Orally active and effective against FLT3 mutants such as D835Y
- Useful for AML research and studies of inhibitor resistance
- Inhibits NDRG1 phosphorylation at Ser330 and suppresses EndMT
- High purity (~99.6%) and fully characterized chemical properties
eMolecules 74397-12-9 | Medchem Express | Limaprost | 2mg | 446273163 | HY-B0683 | MFCD00868275 | 380.525 | C22H36O5
Medchem Express | Limaprost | 2mg | 446273163 | HY-B0683 | 74397-12-9 | MFCD00868275 | 380.525 | C22H36O5
Medchemexpress LLC HY-N1363 25mg Medchemexpress, Royal Jelly acid CAS:14113-05-4 Purity:>98%
Medchemexpress, HY-N1363 25mg Royal Jelly acid CAS:14113-05-4 Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Orotidine 5′-monophosphate trisodium | 68244-58-6 | 5 MG
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide synthesized via the de novo synthesis pathway for DNA synthesis in various microorganisms, including M. tuberculosis, S. cerevisiae, S. typhimurium, and P. falciparum. Its synthesis utilizes phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as substrates, catalyzed by orotate phosphoribosyltransferase (OPRT).
- High purity: 99.0%
- Synonyms include Orotidine monophosphate trisodium and Orotidylic acid trisodium
- Molecular weight: 434.14
- Chemical formula: C10H10N2Na3O11P
- Appears as a white to off-white solid
- Soluble in H2O at 50 mg/mL (115.17 mM)
- Plays a role in DNA synthesis pathway
eMolecules 36953-37-4 | 4-Bromo-2-Hydroxypyridine | AA Blocks LLC | MFCD00234041 | 173.997 | C5H4BrNO | 0.000 | Oc1cc(Br)ccn1 | 5g | 410165386
4-Bromo-2-Hydroxypyridine | AA Blocks LLC | 36953-37-4 | MFCD00234041 | 173.997 | C5H4BrNO | 0.000 | Oc1cc(Br)ccn1 | 5g | 410165386