Acrylic acids and derivatives
eMolecules Medchem Express / Praeruptorin B / 5mg / 437899641 / HY-N0082 / / 73069-28-0 / MFCD09839133 / 426.465 / C24H26O7
Medchem Express / Praeruptorin B / 5mg / 437899641 / HY-N0082 / / 73069-28-0 / MFCD09839133 / 426.465 / C24H26O7
Medchemexpress LLC Skimmin (Umbelliferone glucoside) | 93-39-0 | 1 MG
Skimmin (Umbelliferone glucoside) is a pharmacologically active molecule derived from Hydrangea paniculata, known for its use in traditional Chinese medicine as an anti-inflammatory agent. It exhibits renal protective properties by improving creatinine clearance and reducing kidney injuries. Additionally, Skimmin demonstrates anti-amoebic, anti-cancer, and neuroprotective activities.
- Oral bioavailability
- Anti-inflammatory agent
- Renal protective activity
- Reduces plasma creatinine and kidney injuries
- Anti-amoebic activity against Entamoeba histolytica
- Anti-cancer activity
- Neuroprotective activity
- Reduces cardiac fibrosis
- Decreases inflammatory markers in cardiac tissues
- Potential for diabetes and related disease research
Medchemexpress LLC Kavain | 3155-48-4 | 50 MG
Kavain is a kavalactone isolated from *Piper methysticum*. It exhibits anxiolytic properties and acts as a positive modulator of γ-Aminobutyric acid type A (GABAA) receptors. This product is intended for research use.
- Isolated from *Piper methysticum*.
- Exhibits anxiolytic properties in animals and humans.
- Positively modulates γ-Aminobutyric acid type A (GABAA) receptors.
- Modulatory effect is unaffected by flumazenil.
- Shows greater enhancement at α4β2δ than at α1β2γ2L GABAARs.
Medchemexpress LLC (R)-(+)-Bay-K-8644 | 98791-67-4 | C16H15F3N2O4 | 100 MG
(R)-(+)-Bay-K-8644 is a calcium channel inhibitor that inhibits Ba2+ currents (IBa) with an IC50 of 975 nM. While the conventional racemic mixture of Bay K 8644 is widely used as an L-type Ca2+ channel agonist, the (R)-(+)-isomer acts as an antagonist.
- Calcium channel inhibitor
- Inhibits Ba2+ currents (IBa) with an IC50 of 975 nM
- Acts as an antagonist
- (R)-(+)-isomer, distinguishing it from the L-type Ca2+ channel agonist racemic mixture
Alkali Scientific Lauryl Tryptose Broth, 1 Kg
Lauryl Tryptose Broth, available in a 1kg pack, is used for laboratory testing to cultivate and isolate bacteria in microbiological research. The medium supports the growth of a wide range of microorganisms, making it a key component in food safety and clinical microbiology. It is especially useful for selective enrichment and identification of pathogenic bacteria, ensuring precise microbial analysis in laboratory environments.
Medchemexpress LLC HY-N0885 5mg Medchemexpress, Telocinobufagin CAS:472-26-4 Purity:>98%
Medchemexpress, HY-N0885 5mg Telocinobufagin CAS:472-26-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Alkali Scientific Lauryl Tryptose Broth, 2 Kilograms
Lauryl Tryptose Broth, 2 Kilograms, is a selective broth medium used for the growth and differentiation of coliform bacteria in microbiological testing. Ideal for laboratory applications, this medium supports the growth of a broad range of microorganisms, including fecal coliforms, making it highly valuable for water and food quality testing. This quality-controlled product ensures accurate, reliable results in all testing scenarios.
Medchemexpress LLC HY-B0146 100mg , Verteporfin CL 318952 CAS:129497-78-5 Purity:98%
Medchemexpress, HY-B0146 100mg Verteporfin CL 318952 CAS:129497-78-5 Formula:C41H42N4O8 Purity:98% Verteporfin is a benzoporphyrin derivative monoacid ring A, and can inhibit the activity of YAP . Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Praeruptorin A | 73069-27-9 | MFCD31561439 | 99.6% | 386.40 | C21H22O7 | 10 MG
Praeruptorin A is a natural coumarin constituent used as a research reagent and analytical standard with reported anti-inflammatory activity via NF-κB inhibition.
- Pack contains 10 mg of Praeruptorin A.
- High purity (99.57%).
- Solid, white to off-white appearance.
- Molecular formula C21H22O7, molecular weight 386.40.
- CAS number 73069-27-9.
- Store at 4°C and protect from light; in solvent: -80°C for 6 months, -20°C for 1 month.
- Intended for in vitro research and analytical applications.
Sigma Aldrich Fine Chemicals Biosciences Atractylenolide III >=98% (HPLC) | 73030-71-4 | MFCD00238543 | 10MG
Atractylenolide III >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 248.32 | 73030-71-4 | MFCD00238543 | 10MG
Santa Cruz Biotechnology SODIUM ACRYLATE 25 G
Sodium acrylate | Purity: ≥96% | Mol WT: 94.04 | 7446-81-3 | 25 g
Medchemexpress LLC C26H29F3N4O6S | 2387505-73-7 | 99.7% | 582.59 | 25 MG
J-2156 TFA is a highly potent, selective somatostatin receptor type 4 (SST4 receptor) agonist. It has IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively. It also demonstrates anti-inflammatory activity and is used for relieving mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws in rats.
- High potency and selectivity for somatostatin receptor type 4 (SST4 receptor)
- IC50 of 0.05 nM for human SST4 and 0.07 nM for rat SST4 receptors
- Possesses anti-inflammatory activity
- Effective in alleviating mechanical allodynia and mechanical hyperalgesia in rats
- Binds with nanomolar affinity to human SST4 (Ki=1.2 nM)
- Over 400-fold subtype-selective against other somatostatin receptors (hsst1, hsst2, hsst3, hsst5)
Medchemexpress LLC J-2156 | 848647-56-3 | 99.9% | 468.57 | 50 MG
J-2156 is a highly potent and selective somatostatin receptor type 4 (SST4 receptor) agonist, with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors respectively. It is used for the relief of mechanical allodynia and mechanical hyperalgesia in rat models, demonstrating nanomolar affinity for human SST4 receptors and over 400-fold subtype-selectivity against other somatostatin receptors.
- Highly potent and selective somatostatin receptor type 4 (SST4) agonist.
- Exhibits IC50s of 0.05 nM for human SST4 and 0.07 nM for rat SST4 receptors.
- Provides relief for mechanical allodynia and hyperalgesia in rats.
- Binds to human somatostatin receptor subtype 4 with a Ki of 1.2 nM.
- Offers over 400-fold subtype-selectivity against other somatostatin receptors.
- For research use only.
Medchemexpress LLC Resatorvid (TAK-242) | 243984-11-4 | 99.95% | 361.82 | 500 MG
Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. It inhibits NO, TNF-α, and IL-6 production with IC50s of 1.8 nM, 1.9 nM, and 1.3 nM, respectively. This compound downregulates the expression of TLR4 downstream signaling molecules MyD88 and TRIF, inhibits autophagy, and plays a pivotal role in various inflammatory diseases.
- Selectively inhibits toll-like receptor 4 (TLR4).
- Inhibits nitric oxide (NO), TNF-α, and IL-6 production.
- Downregulates the expression of TLR4 downstream signaling molecules MyD88 and TRIF.
- Inhibits autophagy.
- Plays a pivotal role in various inflammatory diseases.
- Suppresses production from LPS-stimulated human peripheral blood mononuclear cells (PBMCs).
- Reverses LPS-induced body weight loss and muscle loss in mice models.
Medchemexpress LLC Hydroxypropyl starch | 9049-76-7 | MFCD00081709 | 780.8 g/mol | C31H56O22 | 25g
Hydroxypropyl starch (2-Hydroxypropyl starch) is a type of modified starch used as a food additive Hydroxypropyl starch is not absorbed intact by the gut but is significantly hydrolyzed by intestinal enzymes and then fermented by intestinal microbiota[1][2]