Boronic acid derivatives
Cayman Chemical KT 5720 Inhibitors
A potent inhibitor of PKA; blocks PKA signaling through competitive inhibition of ATP (Ki = 60 nM); inhibits phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β
Cayman Chemical CAY10486 Fatty Acids and Deriv
An inhibitor of ACAT; inhibits human ACAT-1 and ACAT-2 (IC50s = ~60 µM for both); inhibits copper-mediated oxidation of LDL by about 20% at 3 µM
Cayman Chemical 16 SHETE Fatty Acids and Deriv
An inhibitor of proximal tubule ATPase activity; a minor CYP450 metabolite of arachidonic acid
Cayman Chemical CAY10487 Fatty Acids and Deriv
An antioxidant with anti-atherogenic activity; inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity; dietary administration (0.05%) reduces the percent area occupied by the atherosclerotic lesion in rabbits to 16.1% from 53.5% in control rabbits; inhibits copper-mediated oxidation of LDL by ~75% at 2 µM
eMolecules 227305-69-3 | 2,3-Dihydrobenzofuran-5-boronic acid | Ambeed | MFCD02681979 | 163.97 | C8H9BO3 | 96 | OB(O)c1ccc2OCCc2c1 | 1g | 552572444
Medchem Express | Iriflophenone | 5mg | 532150258 | HY-N4010 | 52591-10-3 | MFCD20260852 | 246.218 | C13H10O5
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![eMolecules 1447606-90-7 | 7-CHLORO-2-(4-FLUOROPHENYL)-1H-PYRROLO[2,3-C]PYRIDINE | MFCD25542409 | 0.1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502180781.JPG-250.jpg)
eMolecules 1447606-90-7 | 7-CHLORO-2-(4-FLUOROPHENYL)-1H-PYRROLO[2,3-C]PYRIDINE | MFCD25542409 | 0.1g
Ambeed | 67-Dichloroquinoxaline | 250mg | 600845128 | A660431 | 19853-64-6 | MFCD00456885 | 199.030 | C8H4Cl2N2
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Medchemexpress LLC 4-(4-carbamoylphenoxy)benzamide | 6336-34-1 | 99.8% | 256.26 g/mol | C14H12N2O3 | 100MG
OUL35 (NSC39047) is a small-molecule, selective inhibitor of ARTD10 (PARP10) used as a research reagent to probe PARP10 activity and related cellular pathways. It exhibits potent biochemical activity and has characterized solubility and storage properties for use in biochemical and cell-based studies.
- Selective ARTD10 (PARP10) inhibitor with IC50 329 nM.
- Cytoprotective activity in HeLa cells (IC50 1.35 μM).
- High purity (99.8%) and solid, white to off-white appearance.
- Soluble in DMSO (83.33 mg/mL); in vivo formulations ≥ 2.08 mg/mL in 10% DMSO/90% SBE-β-CD or corn oil.
- Store at 4°C and protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Molecular formula C14H12N2O3; molecular weight 256.26 g/mol.
Chem-Impex International, Inc. 4-Carboxyphenylboronic acid | MFCD00151801 | 100G
4-Carboxyphenylboronic acid, MFCD00151801, 100G
Accela Chembio Inc MF: C8H9O4B | MW: 179.97 | >97% | Flash Point: 170.9 celsius | BP: 359 celsius at 760 mmHg.
MF: C8H9O4B | MW: 179.97 | >97% | Flash Point: 170.9 celsius | BP: 359 celsius at 760 mmHg.
eMolecules 1150114-66-1 | 3-Carboxy-5-methylphenylboronic acid | Combi-Blocks | MFCD12025977 | 179.970 | C8H9BO4 | 98.000 | Cc1cc(cc(c1)C(O)=O)B(O)O | 1g | 205382243
3-Carboxy-5-methylphenylboronic acid | Combi-Blocks | 1150114-66-1 | MFCD12025977 | 179.970 | C8H9BO4 | 98.000 | Cc1cc(cc(c1)C(O)=O)B(O)O | 1g | 205382243
Cayman Chemical CAY10602 Fatty Acids and Deriv
A SIRT1 activator; inhibits LPS-induced TNF-α release in THP-1 cells at 20 and 60 µM; decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and MDA, in A549, MDA-MB-231, and Hs 578T cells at 5 µM; reduces oleic acid-induced apoptosis and lipid accumulation in HepG2 cells when used at a concentration of 20 µM
Cayman Chemical CAY10602 Fatty Acids and Deriv
A SIRT1 activator; inhibits LPS-induced TNF-α release in THP-1 cells at 20 and 60 µM; decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and MDA, in A549, MDA-MB-231, and Hs 578T cells at 5 µM; reduces oleic acid-induced apoptosis and lipid accumulation in HepG2 cells when used at a concentration of 20 µM