Organic phosphoric acids and derivatives
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Apexbio Technology LLC L-755,507 159182-43-1 10mg
L-755 507 (CAS 159182-43-1) is a benzene sulfonamide derivative that functions as a partial agonist of the human 3-adrenergic receptor a G protein-coupled receptor involved in promoting lipolysis in adipose tissue L-755 507 exhibits high affinity for the 3 receptor (IC50 13 nM EC50 0 43 nM) and demonstrates over 440-fold selectivity compared to 1 and 2 adrenergic receptors In rhesus monkey models L-755 507 induces lipolysis in adipocytes (EC50 3 9 nM) and acutely elevates metabolic rate by approximately 30% following intravenous administration These properties make L-755 507 a valuable tool for studying 3-adrenergic receptor-mediated lipid metabolism and energy expenditure in preclinical research
