Vinylogous acids
eMolecules Ethyl 3-ethoxyprop-2-enoate | Combi-Blocks | 1001-26-9 | | 144.170 | C7H12O3 | 95.000 | CCOC=CC(=O)OCC | 25g | 205384295
Ethyl 3-ethoxyprop-2-enoate | Combi-Blocks | 1001-26-9 | | 144.170 | C7H12O3 | 95.000 | CCOC=CC(=O)OCC | 25g | 205384295
Medchemexpress LLC Boc-val-cit-pab-pnp | 870487-10-8 | 99.6% | 644.67 | C30H40N6O10 | 50 MG
Boc-Val-Cit-PAB-PNP is a protease-cleavable linker used to construct antibody-drug conjugates (ADCs). It releases payloads after intracellular proteolytic cleavage and is supplied as a solid with high purity.
- Cleavable val-cit peptide linker releasing payload upon proteolysis
- Para-aminobenzyl spacer with p-nitrophenyl leaving group
- High purity suitable for research applications
- Soluble in DMSO at 100 mg/mL with ultrasonic assistance
- Recommended storage: -20°C under nitrogen; in solvent store at -80°C for long-term
- Available in small research scales, e.g. 50 mg
Medchemexpress LLC IACS-8803 disodium | 2243079-36-7 | C20H21FN10Na2O9P2S2 | 10MG
IACS-8803 disodium is a cyclic dinucleotide stimulator of interferon genes (STING) agonist described by investigators at the Institute for Applied Cancer Science (MD Anderson). Supplied as the disodium salt for research use, it shows robust systemic antitumor efficacy in preclinical studies and includes documented solubility and formulation guidance for in vitro and in vivo experiments.
- Potent activation of the STING pathway demonstrated in preclinical studies.
- Water-soluble disodium salt with documented solubility in DMSO, water, and PBS.
- Suggested in vivo formulations and dosing vehicles provided for clear solution preparation.
- High chemical purity suitable for laboratory research applications.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC VU0810464 | 2126040-21-7 | 99.3% | 50 MG
VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.
- Potent and selective activator of GIRK (Kir3) channels
- Displays nanomolar potency for neuronal and GIRK1/4 channels
- Exhibits improved brain penetration
- Reduces stress-induced hyperthermia (SIH) in mice
Medchemexpress LLC Adenylosuccinic acid tetraammonium | >98% | 10 MG
Adenylosuccinic acid tetraammonium is an orally active purine ribonucleoside monophosphate involved in nucleotide cycle metabolism. This compound can be converted into fumaric acid via adenylosuccinate lyase and holds potential for the study of Duchenne muscular dystrophy (DMD).
- Orally active purine ribonucleoside monophosphate
- Plays a role in nucleotide cycle metabolism
- Converts into fumaric acid via adenylosuccinate lyase
- Potential for Duchenne muscular dystrophy (DMD) research
- Ameliorates murine Duchenne muscular dystrophy symptoms in vivo
Medchemexpress LLC Sparfosic acid | 51321-79-0 | 99.3% | 255.12 g/mol | C6H10NO8P | 5 MG
Sparfosic acid is N-phosphonacetyl-L-aspartic acid, a DNA antimetabolite and potent inhibitor of aspartate transcarbamoyl transferase (ATCase). It is used in biochemical and cell-based research to disrupt de novo pyrimidine biosynthesis and has been reported to increase the cytotoxic effect of 5-fluorouracil combined with interferon-alpha in cancer cell models.
- Inhibits aspartate transcarbamoyl transferase (ATCase).
- Acts as a DNA antimetabolite affecting pyrimidine biosynthesis.
- Reported to enhance cytotoxicity of 5-fluorouracil plus interferon-alpha.
- High purity (99.3%) suitable for biochemical studies.
- Available in small research pack sizes (1 mg-100 mg).
- Molecular formula C6H10NO8P; molecular weight 255.12 g/mol.
eMolecules 1-(2-HYDROXYETHYL)CYCLOBUTANOL | 83237-27-8 | MFCD22056276 | 1g
AstaTech | 1-(2-HYDROXYETHYL)CYCLOBUTANOL | 1g | 392628733 | F30304 | 95.000 | 83237-27-8 | MFCD22056276 | 116.160 | C6H12O2
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eMolecules 1-(AMINOMETHYL)CYCLOBUTANECARBONITRILE HCL | 1951441-21-6 | MFCD27997392 | 0.25g
AstaTech | 1-(AMINOMETHYL)CYCLOBUTANECARBONITRILE HCL | 0.25g | 293373432 | 72978 | 95.000 | 1951441-21-6 | MFCD27997392 | 146.620 | C6H11ClN2
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Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | MFCD09878272 | 99.9% | 399.48 | C23H29NO5 | 5 MG
Tesmilifene fumarate is a research-grade small molecule that acts as an H1C (histamine) receptor antagonist. It is reported to potentiate a wide range of cytotoxic agents and may offer some protection to normal cells. The compound is supplied for laboratory research and analytical applications.
- Acts as an H1C receptor antagonist.
- Potentiates a wide range of cytotoxic agents.
- May offer some protection to normal cells.
- Molecular formula C23H29NO5 and molecular weight 399.48.
- Purity typically 99.85%.
- Available in small research quantities, including 5 MG packs.
Medchemexpress LLC Dehydroepiandrosterone sulfate | 651-48-9 | 99.9% | 368.49 | 50 MG
Dehydroepiandrosterone sulfate | 651-48-9 | 99.9% | 368.49 | 50 MG
Medchemexpress LLC LIT-001 | 2245072-21-1 | 98.6% | 645.70 | C30H34F3N7O4S | 50MG
LIT-001 is a nonpeptide oxytocin receptor (OT-R) agonist used as a research tool compound. It exhibits OT-R activity (EC50 = 55 nM; Ki = 226 nM) and has been reported to improve social interaction in a mouse model. The compound is a white to off-white solid (molecular formula C30H34F3N7O4S, MW 645.70), provided with analytical documentation, and is typically stored at -20 °C. It is highly soluble in DMSO for in vitro use.
- Nonpeptide oxytocin receptor agonist with EC50 = 55 nM and Ki = 226 nM.
- Demonstrated improvement of social interaction in a mouse model.
- High purity suitable for in vitro studies.
- High solubility in DMSO enables straightforward formulation.
- Provided with analytical documentation such as COA, LC-MS, and H NMR.
- Solid form stable when stored at -20 °C under sealed, dry conditions.
Matrix Scientific ETHYL (ETHOXYMETHYLENE)CYA-100
Ethyl (ethoxymethylene)cyanoacetate Mf C8h11no3 Mw 169.18 Cas 94-05-3 Mdl MFCD00009136
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | 4077-47-8 | MFCD00209504 |
2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | Purity: >=98% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 |
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | 99.9% | 399.48 g/mol | C23H29NO5 | 10 MG
Tesmilifene fumarate is the fumarate salt of tesmilifene (DPPE fumarate), a small-molecule H1C receptor antagonist reported to potentiate a wide range of cytotoxic chemotherapies while offering some protection to normal cells. It is supplied for research use in solid and ready-to-use solution formats.
- Potentiates cytotoxic chemotherapy in research settings.
- Acts as an H1C receptor antagonist.
- High purity (≈99.9%).
- Molecular weight 399.48 g/mol; formula C23H29NO5.
- Available in multiple vial sizes and as a 10 mM solution in DMSO.
- Intended for research use and stored at -20°C.