Azepines
TARGETMOL CHEMICALS INC ESLICARBAZEPINE ACETATE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. purity: 99%
Apexbio Technology LLC Oxcarbazepine 28721-07-5 10mM (in 1mL DMSO)
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 1 ML
Oxcarbazepine (GP 47680) is an anti-epileptic agent that functions as a sodium channel blocker. It significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits both anti-cancer and anticonvulsant effects.
- Inhibits glioblastoma cell growth with IC50 values of 12.35 μg/mL for U87 cell lines and 9.45 μg/mL for T98 cell lines.
- Protects mice and rats against generalized tonic-clonic seizures induced by electroshock.
- No tolerance to anticonvulsant effect observed in rats treated daily for 4 weeks.
- Functions as a sodium channel blocker.
- Induces apoptosis or G2/M arrest in glioblastoma cell lines.
Medchemexpress LLC Oxcarbazepine (Standard) | 28721-07-5 | 99.9% | C₁₅H₁₂N₂O₂ | 100 MG
Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine, intended for research and analytical applications. It is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects. This product is for research use only.
- Analytical standard
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Sodium channel blocker
- Inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Apexbio Technology LLC Eslicarbazepine acetate 236395-14-5 100mg
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Cayman Chemical CarbamazepIn 10 11-epoxIde 5mg
An active metabolite of carbamazepine; has anticonvulsant activity against maximal electroshock-induced seizures in mice; has been found in wastewater effluent
![eMolecules 84030-20-6 | 1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine | Combi-Blocks | MFCD00043004 | 153.229 | C8H15N3 | 95.000 | CN1CCCN2CCCN=C12 | 10g | 267193191](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000160862.jpg-250.jpg)
eMolecules 84030-20-6 | 1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine | Combi-Blocks | MFCD00043004 | 153.229 | C8H15N3 | 95.000 | CN1CCCN2CCCN=C12 | 10g | 267193191
1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine | Combi-Blocks | 84030-20-6 | MFCD00043004 | 153.229 | C8H15N3 | 95.000 | CN1CCCN2CCCN=C12 | 10g | 267193191
Apexbio Technology LLC Carbamazepine 298-46-4 10mM (in 1mL DMSO)
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 50 MG
Oxcarbazepine is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects.
- Sodium channel blocker
- Significantly inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Medchemexpress LLC Carbamazepine 10,11-epoxide | 36507-30-9 | 99.1% | 252.27 | 1 ML
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect and can be used for the research of seizures.
- Orally active metabolite
- Anticonvulsant effect
- Suitable for research of seizures