Azepines
Sigma Aldrich (2-Cyclobutylethyl)amine hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-Bromo-5-methoxyaniline
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich (1H-Indol-3-yl)methanamine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Apexbio Technology LLC Carbamazepine 298-46-4 10mM (in 1mL DMSO)
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Medchemexpress LLC Oxcarbazepine (Standard) | 28721-07-5 | 99.9% | C₁₅H₁₂N₂O₂ | 100 MG
Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine, intended for research and analytical applications. It is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects. This product is for research use only.
- Analytical standard
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Sodium channel blocker
- Inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 50 MG
Oxcarbazepine is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects.
- Sodium channel blocker
- Significantly inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Apexbio Technology LLC Eslicarbazepine acetate 236395-14-5 100mg
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Cayman Chemical CarbamazepIn 10g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Sigma Aldrich Fine Chemicals Biosciences BIA 2-093 >=98% (HPLC), solid | 236395-14-5 | MFCD06798333 | 10MG
BIA 2-093 >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 296.32 | 236395-14-5 | MFCD06798333 | 10MG
Cayman Chemical Conduritol B epoxide 25MG
An irreversible inhibitor of GBA (IC50 = 9 μM); does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase