Azepines
Sigma Aldrich Hexahydro-4-methylphthalic anhydride, mixture of cis and trans
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich (1H-Indol-3-yl)methanamine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-Bromo-5-methoxyaniline
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Oxcarbazepine (Standard) | 28721-07-5 | 99.9% | C₁₅H₁₂N₂O₂ | 100 MG
Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine, intended for research and analytical applications. It is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects. This product is for research use only.
- Analytical standard
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Sodium channel blocker
- Inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 1 ML
Oxcarbazepine (GP 47680) is an anti-epileptic agent that functions as a sodium channel blocker. It significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits both anti-cancer and anticonvulsant effects.
- Inhibits glioblastoma cell growth with IC50 values of 12.35 μg/mL for U87 cell lines and 9.45 μg/mL for T98 cell lines.
- Protects mice and rats against generalized tonic-clonic seizures induced by electroshock.
- No tolerance to anticonvulsant effect observed in rats treated daily for 4 weeks.
- Functions as a sodium channel blocker.
- Induces apoptosis or G2/M arrest in glioblastoma cell lines.
Cayman Chemical CarbamazepIn 10 11-epoxIde 5mg
An active metabolite of carbamazepine; has anticonvulsant activity against maximal electroshock-induced seizures in mice; has been found in wastewater effluent
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 50 MG
Oxcarbazepine is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects.
- Sodium channel blocker
- Significantly inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Apexbio Technology LLC Oxcarbazepine 28721-07-5 10mM (in 1mL DMSO)
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Apexbio Technology LLC Eslicarbazepine acetate 236395-14-5 100mg
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Medchemexpress LLC Carbamazepine 10,11-epoxide | 36507-30-9 | 99.1% | 252.27 | 1 ML
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect and can be used for the research of seizures.
- Orally active metabolite
- Anticonvulsant effect
- Suitable for research of seizures
Medchemexpress LLC Carbamazepine 10,11-epoxide | 36507-30-9 | 99.1% | 252.27 | 100 MG
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine. It has an anticonvulsant effect and can be used for the research of seizures.
- Orally active metabolite
- Has anticonvulsant effect
- Used for research of seizures
- For research use only
- Appearance: Solid, off-white to light yellow
TARGETMOL CHEMICALS INC Eslicarbazepine 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures. Purity 99.23%
Cayman Chemical Soluble Epoxide Hydrolase hu
Source: Active recombinant human N-terminal His-tagged sEH expressed in insect cells • Amino acids: 2-555 (full length) • MW: 64 kDa