Azepines
Aobchem 3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 250mg
3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 250mg
Aobchem 3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 1g
3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 1g
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 1 ML
Oxcarbazepine (GP 47680) is an anti-epileptic agent that functions as a sodium channel blocker. It significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits both anti-cancer and anticonvulsant effects.
- Inhibits glioblastoma cell growth with IC50 values of 12.35 μg/mL for U87 cell lines and 9.45 μg/mL for T98 cell lines.
- Protects mice and rats against generalized tonic-clonic seizures induced by electroshock.
- No tolerance to anticonvulsant effect observed in rats treated daily for 4 weeks.
- Functions as a sodium channel blocker.
- Induces apoptosis or G2/M arrest in glioblastoma cell lines.
Apexbio Technology LLC Eslicarbazepine acetate 236395-14-5 100mg
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Aobchem 4-(3-Chloropyridin-4-yl)tetrahydro-2H-pyran-4-ol | 97% | CAS 2918851-44-0 | C10H12ClNO2 | 250mg
4-(3-Chloropyridin-4-yl)tetrahydro-2H-pyran-4-ol | 97% | CAS 2918851-44-0 | C10H12ClNO2 | 250mg
Aobchem 4-(2-Chloro-4-pyridinyl)tetrahydro-2H-pyran-4-ol | 95% | CAS 1451186-65-4 | C10H12ClNO2 | 1g
4-(2-Chloro-4-pyridinyl)tetrahydro-2H-pyran-4-ol | 95% | CAS 1451186-65-4 | C10H12ClNO2 | 1g
Aobchem 4-Bromo-3 5-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole | ≥97% | CAS 1187385-69-8 | C10H15BrN2O | 500mg
4-Bromo-3 5-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole | ≥97% | CAS 1187385-69-8 | C10H15BrN2O | 500mg
Medchemexpress LLC 1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester | 286961-14-6 | 97.0% | 309.21 | 25 G
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent. It can be used as a biological material or organic compound for life science related research.
- Biochemical reagent.
- Used as biological material or organic compound.
- Suitable for life science research.
Apexbio Technology LLC Carbamazepine 298-46-4 10mM (in 1mL DMSO)
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Cayman Chemical Dexamethason 9 11-epoxIde 1g
A potential impurity found in preparations of dexamethasone; an autooxidative degradation product formed under alkaline conditions
Medchemexpress LLC Carbamazepine (Standard) | 298-46-4 | 100.0% | 100 MG
Carbamazepine (Standard) is the analytical standard of Carbamazepine, intended for research and analytical applications. It is an orally active pressure-sensitive sodium ion channel blocker, blocking voltage gated Na+, Ca2+, and K+ channels, and also acts as an HDAC inhibitor. It is an anticonvulsant used for research of epilepsy and neuropathic pain, commonly utilized in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Carbamazepine
- Intended for research and analytical applications
- Orally active pressure-sensitive sodium ion channel blocker
- Blocks voltage gated Na+, Ca2+, and K+ channels
- Acts as an HDAC inhibitor
- Anticonvulsant for epilepsy and neuropathic pain research
- Used in HPLC, GC, and MS experiments
Apexbio Technology LLC CARBAMAZEPINE-D10-5MG
Carbamazepine-d10 (CAS No 132183-78-9) is a deuterated form of carbamazepine primarily used in biomedical research as a stable isotope-labeled internal standard It originates from the anticonvulsant drug carbamazepine which targets voltage-gated sodium channels inhibiting repetitive neuronal firing In vitro activities are generally observed in the nanomolar to low micromolar range making it useful for precise pharmacokinetic and bioavailability studies Typical applications include studying metabolic pathways in cell models and examining drug interactions in animal studies Additionally it assists in drug screening assays ensuring accurate quantification Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Carbamazepine (standard) | 298-46-4 | 99.97% | 50 MG
Carbamazepine (Standard) is an orally active, pressure-sensitive sodium ion channel blocker, demonstrating an IC50 of 131 μM. This compound also blocks voltage-gated Na+, Ca2+, and K+ channels, and acts as a histone deacetylase (HDAC) inhibitor with an IC50 of 2 μM. It is primarily used as an anticonvulsant in research settings. This analytical standard is suitable for qualitative, quantitative, and methodological research experiments, including applications in HPLC, GC, and MS.
- Functions as an anticonvulsant for epilepsy and neuropathic pain research.
- Blocks voltage-gated sodium, calcium, and potassium channels.
- Inhibits histone deacetylase (HDAC).
- Supplied as an analytical standard for various research applications.
Aobchem 2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 500mg
2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 500mg