Azolines
Medchemexpress LLC Thiol-PEG5-thiol | 89141-22-0 | 1 G
Thiol-PEG5-thiol (Bis-PEG5-thiol) is a bifunctional thiol cross-linker agent.
- Molecular formula: C₁₂H₂₆O₅S₂
- Molecular weight: 314.46
- Target: Biochemical assay reagents
Medchemexpress LLC Propanoic acid, 3-(2-mercaptoethoxy)- | 1260092-48-5 | 95.0% | 150.20 g/mol | C5H10O3S | 100 MG
Thiol-PEG1-acid (SH-PEG1-COOH) is a short polyethylene glycol derivative with a terminal thiol and a carboxylic acid. It functions as a bifunctional linker reagent for bioconjugation, enabling selective thiol coupling and formation of amide or ester bonds at the carboxyl terminus. Typical applications include linker synthesis, surface modification, and conjugation to peptides, proteins, or surfaces. Purity is typically 95%.
- Provides a terminal thiol for selective thiol coupling reactions.
- Offers a carboxyl group for amide or ester bond formation.
- Short PEG spacer minimizes steric hindrance in conjugates.
- Soluble in DMSO (approx. 100 MG/ML) for convenient stock solutions.
- Store pure material at -20°C; in solvent store at -80°C for extended stability.
Medchemexpress LLC Thiol-PEG2-acid | 1379649-73-6 | 96.0% | 194.25 | 1 G
Thiol-PEG2-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Utilized in PROTAC synthesis
- Acts as a PROTAC linker
- Supports targeted protein degradation
- Features a molecular formula of C7H14O4S
- Appears as a colorless to light yellow liquid
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 50 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein. PROTACs harness the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 5-Chloro-2-mercaptobenzimidazole | 25369-78-2 | MFCD01658762 | 25g
Combi-Blocks | 5-Chloro-2-mercaptobenzimidazole | 25g | 517031871 | QB-9061 | 95.000 | 25369-78-2 | MFCD01658762 | 184.640 | C7H5ClN2S
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Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 50 MG
VH 101, thiol (compound 20) is a VHL ligand primarily used for the synthesis of PROTACs. This product is intended for research purposes only and not for patient use.
- VHL ligand for PROTAC synthesis
- Intended for research use only
- Molecular weight: 534.67
- Appearance: solid
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL
Medchemexpress LLC 2,4-Dimethyl-1H-imidazole-5-carbaldehyde | 68282-52-0 | 99.86% | C6H8N2O | 25 MG
This 2,4-Dimethyl-1H-imidazole-5-carbaldehyde is a drug intermediate for the synthesis of various active compounds. It is for research use only and not sold to patients. It appears as a solid with a light yellow to yellow color.
- Used as a drug intermediate
- Aids in the synthesis of active compounds
- For research use only
- Appears as a solid
- Light yellow to yellow color
Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 25 MG
VH 101, thiol (compound 20) is a VHL ligand primarily used for the synthesis of PROTACs, targeting VHL. This product is intended for research use only and has not been fully validated for medical applications.
- VHL ligand for PROTAC synthesis
- Targets VHL
- For research use only
Medchemexpress LLC m-PEG-thiol (MW 20000) | 95.0% | 100 MG
m-PEG-thiol (MW 20000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds designed with two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a specific protein
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
Medchemexpress LLC m-PEG6-thiol | 441771-60-4 | >98% | C13H28O6S | 250 MG
m-PEG6-thiol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG-thiol (MW 5000) | 88778-21-6 | 99.9% | 500 MG
M-PEG-thiol (MW 5000) is a PEG-based PROTAC linker employed in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two different ligands: one for an E3 ubiquitin ligase and the other for the target protein.
- Utilized as a PEG-based PROTAC linker
- Supports the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC m-PEG8-thiol | 651042-83-0 | 99.9% | C17H36O8S | 100 MG
m-PEG8-thiol is a PEG-based PROTAC linker that facilitates the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are bifunctional molecules comprising two ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein, thereby exploiting the intracellular ubiquitin-proteasome system for selective protein degradation.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs for targeted protein degradation
- Exploits the intracellular ubiquitin-proteasome system
![Medchemexpress LLC 3-(benzo[b]thiophen-3-yl)-L-alanine | 72120-71-9 | MFCD00079684 | >98.5% | 221.28 g/mol | C11H11NO2S | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000302824.png-250.jpg)
Medchemexpress LLC 3-(benzo[b]thiophen-3-yl)-L-alanine | 72120-71-9 | MFCD00079684 | >98.5% | 221.28 g/mol | C11H11NO2S | 250 MG
(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is the S-enantiomer of 3-benzothienylalanine, a chiral alanine derivative bearing a benzo[b]thiophene substituent. It is provided as a solid research reagent for use as a building block or reference standard in medicinal chemistry and biochemical studies.
- Chiral S-enantiomer suitable for stereospecific synthesis and stereochemical studies.
- Aromatic benzo[b]thiophene substituent at the 3-position.
- Molecular formula C11H11NO2S and molecular weight 221.28 g/mol.
- Supplied as a solid for laboratory use.
- Appropriate as a building block or reference standard in medicinal chemistry workflows.
- Store protected from light at 4°C; in solvent: -80°C (6 months), -20°C (1 month).
Medchemexpress LLC Thiol-PEG6-alcohol | 194425-46-2 | ≥97.0% | 250 MG
Thiol-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.