Azolines
Medchemexpress LLC 1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 | 345909-96-8 | 99.9% | 119.16 | 5 MG
1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 is the deuterium labeled 1-Methyl-1H-tetrazole-5-thiol. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Medchemexpress LLC Ethanol, 2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]- | 90952-27-5 | 99.9% | 210.29 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365321-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanol, 2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]- | 90952-27-5 | 99.9% | 210.29 | 1 G
Thiol-PEG4-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules connect a ligand for an E3 ubiquitin ligase with a target protein ligand, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Exploits the ubiquitin-proteasome system
- For research use only
eMolecules Ambeed L-Glutathione reduced 1g 490503664 A128528 70-18-8 MFCD00065939 307.320 C10H17N3O6S
Ambeed L-Glutathione reduced 1g 490503664 A128528 70-18-8 MFCD00065939 307.320 C10H17N3O6S
eMolecules Oakwood Chemicals Allyl mercaptan 5g 508866081 099583 870-23-5 MFCD00004894 74.140 C3H6S
Oakwood Chemicals Allyl mercaptan 5g 508866081 099583 870-23-5 MFCD00004894 74.140 C3H6S
Biotium Antibody Labeling Kits Antibody and Protein Labeling Kits Mix n Stain Antibody Labeling Kits CF568 1/EA
Mix-n-Stain CF Dye Nanobody Thiol Labeling Kits are optimized for labeling nanobodies with bright and photostable CF dyes in 2 hours with no purification Kits tolerate common stabilizers Red fluorescent CF568 has Ex/Em at 562/583 nm One labeling of 5-20 ug Nanobody Thiol per kit
Apexbio Technology LLC Methimazole 60-56-0 10mM (in 1mL DMSO)
Methimazole is a small-molecule inhibitor targeting intercellular adhesion molecule-1 (ICAM-1) gene transcription It is designed to modulate ICAM-1 expression thereby regulating cell adhesion processes mediated by immunoglobulin superfamily members and integrins such as LFA-1 and Mac-1 Methimazole exerts its biological activity primarily through modulation of signal transducer and activator of transcription 1 (STAT1) In cell-based studies using thyroid cell models methimazole demonstrates inhibitory activity suppressing ICAM-1 mRNA expression induced by interferon-gamma (IFN- ) and H O Based on these pharmacological properties methimazole holds research potential in studying autoimmune thyroid conditions and as an agent to induce hypothyroidism in animal models for thyroid dysfunction research
Medchemexpress LLC Thiol-PEG6-alcohol | 194425-46-2 | ≥97.0% | 1 G
Thiol-PEG6-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs function by connecting two distinct ligands, one for an E3 ubiquitin ligase and the other for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC Thiol-PEG4-acid | 749247-06-1 | 95.0% | 25 MG
Thiol-PEG4-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting a protein for degradation. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity of 95.0%
- Molecular weight: 282.35
- Chemical formula: C11H22O6S
- Appearance: colorless to light yellow liquid
- Storage at 4°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Density: 1.156±0.06 g/cm3
Medchemexpress LLC Propanoic acid, 3-(2-mercaptoethoxy)- | 1260092-48-5 | 95.0% | 150.20 g/mol | C5H10O3S | 50 MG
Thiol-PEG1-acid (SH-PEG1-COOH) is a short polyethylene glycol derivative bearing a reactive thiol (-SH) and a terminal carboxylic acid (-COOH). It is supplied as a colorless to light yellow liquid and is intended for use as a linker in bioconjugation and PEGylation reactions. Store pure material frozen and protect solutions from long-term degradation.
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 500 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein via a linker.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Amine-PEG-thiol (MW 2000) | 93.0% | 50 MG
Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound functions by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins, and it appears as a white to off-white solid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- White to off-white solid appearance
Medchemexpress LLC Thiol-PEG2-acid | 1379649-73-6 | 96.0% | 194.25 | 100 MG
Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs themselves contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein, and they exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. For research use only. We do not sell to patients.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 50 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein. PROTACs harness the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 5-Chloro-2-mercaptobenzimidazole | 25369-78-2 | MFCD01658762 | 25g
Combi-Blocks | 5-Chloro-2-mercaptobenzimidazole | 25g | 517031871 | QB-9061 | 95.000 | 25369-78-2 | MFCD01658762 | 184.640 | C7H5ClN2S
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Medchemexpress LLC m-PEG-thiol (MW 10000) | 98.0% | 100 MG
m-PEG-thiol (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Appearance: Solid, white to off-white
- Shipping: Room temperature in continental US; may vary elsewhere