Azolines
![Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | >98.0% | COCCOCCS.[MW 2000].[n] | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | >98.0% | COCCOCCS.[MW 2000].[n] | 250 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker designed for research use only, specifically in the synthesis of PROTACs. It presents as a white to yellow solid with an average molecular weight of 2000.
- PEG-based PROTAC linker
- For research use only
- White to yellow solid appearance
- Average molecular weight of 2000
- Can be used in the synthesis of PROTACs
![Medchemexpress LLC (S)-2-amino-3-(benzo[b]thiophen-3-yl)propanoic acid | 72120-71-9 | MFCD00079684 | >98.5% | 221.28 g/mol | C11H11NO2S | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299603.png-250.jpg)
Medchemexpress LLC (S)-2-amino-3-(benzo[b]thiophen-3-yl)propanoic acid | 72120-71-9 | MFCD00079684 | >98.5% | 221.28 g/mol | C11H11NO2S | 1 G
(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is the (S)-enantiomer of 3-benzothienylalanine, an alanine derivative bearing a benzothiophene substituent. Supplied as a research-grade amino acid, it is used as a building block in medicinal chemistry and peptide synthesis to introduce a benzothiophene side chain for SAR and conformational studies.
- Enantiomerically defined (S)-configuration for stereospecific synthesis.
- Benzothiophene side chain to modulate hydrophobic and aromatic interactions.
- Suitable as an amino acid building block for peptide and small-molecule synthesis.
- White to off-white solid, convenient for handling and storage.
- Provided for research use only.
- Available in multiple pack sizes for screening and scale-up.
Medchemexpress LLC Hexa(ethylene glycol) dithiol | 89141-22-0 | 500 MG
Hexa(ethylene glycol) dithiol, also known as Thiol-PEG5-thiol (Bis-PEG5-thiol), is a bifunctional thiol cross-linker agent. It is intended for research and development applications, specifically targeting biochemical assay reagents. The chemical has a formula of C12H26O5S2 and a molecular weight of 314.46.
- Bifunctional thiol cross-linker agent
- Targets biochemical assay reagents
- Chemical formula: C12H26O5S2
- Molecular weight: 314.46
- Relative density: 1.113 g/cm³ at 25 °C
- Flash point: >110 °C
- Recommended storage at 2-8 °C
- Handle under nitrogen, protected from moisture
Medchemexpress LLC Thiol-PEG8-acid | 866889-02-3 | 97.0% | 250 MG
Thiol-PEG8-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Cayman Chemical MethImazole 100mg
An inhibitor of thyroid hormone synthesis; a substrate of thyroid peroxidase; traps oxidized iodide and prevents its use by thyroglobulin; inhibits absorption of radiolabeled iodide by the thyroid gland in rats at 0.4 mg/kg; reduces the incidence of lymphocytic thyroiditis in the insulin-dependent type 1 diabetic BB/W rat; has been used to induce hypothyroidism in mice
Medchemexpress LLC m-PEG-thiol | 134874-49-0 | MFCD00803682 | 90.0% | 750 (average) | (C2H4O)nC3H8OS | 250 MG
m-PEG-thiol (average MW 750) is a methoxy-terminated polyethylene glycol bearing a terminal thiol group, supplied as a solid reagent for bioconjugation and nanoparticle surface functionalization. It is commonly used to thiolate DNA and to anchor polymers or biomolecules onto gold and other metal surfaces via thiol-gold chemistry, supporting applications in nanostructure assembly, biosensing, and drug delivery.
- Provides terminal thiol for covalent attachment to metal surfaces and thiol-reactive chemistries.
- Average molecular weight 750 for a short PEG spacer length.
- Supplied as a solid suitable for solution-phase conjugation.
- Reported purity approximately 90%.
- Compatible with DNA thiolation and nanoparticle surface modification protocols.
DIASYS DIAGNOSTIC SYSTEMS USA LLC DiaSys Creatinine Jaffe FS is a ready-to-use two component photometric reagent to determine Creatinine in serum, heparin plasma or urine on photometric systems. Each set contains R1=10L, R2=2.5L
Diagnostic reagent for quantitative in vitro determination of creatinine in animal serum, heparin plasma or urine on photometric systems. For veterinary or research use only. Creatinine values are determined to estimate the glomerular filtration rate, an indicator of kidney status. Method: DiaSys Creatinine Jaffe FS is based on the kinetic Jaffé method without deproteinization. The reagent is a liquid-stable kinetic test with a wide measuring range and freedom from lipemia and hemoglobin interference. Reagent 1 contains TRIS, Mg2+, ATP and NAD, reagent 2 contains Mg2+, Hexokinase and Glucose-6-Phospatedehydrogenase. Reagents must be stored refrigerated.
Medchemexpress LLC 5-HT Serotonin Ant 50uL | 50uL
5-HT (Serotonin) Antibody (YA6451) is a Rabbit-derived and non-conjugated IgG monoclonal antibody targeting to 5-HT (Serotonin)
TARGETMOL CHEMICALS INC N-p-Coumaroyl serotonin 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. N-(p-Coumaroyl) Serotonin, a polyphenol isolated from the seeds of safflower, exhibits antioxidant, cardioprotective effects after ischemia, and antitumor activity. It may improve vascular distensibility and reduce cardiovascular risk. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo, and is commonly used in atherosclerosis research. Purity 98.78%
Apexbio Technology LLC Irbesartan 138402-11-6 5mg
Irbesartan (CAS 138402-11-6) is a small molecule antagonist of the angiotensin II type 1 (AT1) receptor By selectively blocking AT1 receptor activity irbesartan inhibits angiotensin II-induced vasoconstriction thereby promoting vasodilation and reducing blood pressure In biomedical research irbesartan serves as an important pharmacological tool to investigate cardiovascular regulation hypertension pathogenesis and related signaling pathways Additionally its use extends to studies exploring therapeutic strategies for cardiovascular disorders
TARGETMOL CHEMICALS INC Irbesartan 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker whose mechanism of action involves antagonizing the Angiotensin 2 Receptor. Purity 99.92%
Medchemexpress LLC Irbesartan | 138402-11-6 | MFCD00864464 | 99.95% | 100 MG
Irbesartan is an orally active angiotensin II type 1 (AT1) receptor blocker. It relaxes blood vessels, lowers blood pressure, and increases the supply of blood and oxygen to the heart. This highly potent and specific AT1 receptor antagonist is used for the research of high blood pressure, heart failure, and diabetic kidney disease.
- Relaxes blood vessels and lowers blood pressure.
- Used for research of high blood pressure, heart failure, and diabetic kidney disease.
- Potent and specific AT1 receptor antagonist with an IC50 of 1.3 nM.
- Inhibits Ang II-induced proliferation of human aortic smooth muscle cells.
- Reduces Th22 cells chemotaxis and suppresses their differentiation.
- Exerts renoprotective effects and relieves systemic inflammation in vivo.
Medchemexpress LLC Creatinine | 60-27-5 | 1 G
Creatinine is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, known for its antioxidation and metabolic regulation activities. Generated from creatine and phosphocreatine in muscle, creatinine serum levels serve as a biomarker for renal function, muscle mass, and clinical outcomes, and for perioperative renal risk assessment. It is used in research for various conditions including neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure.
- Orally active and blood-brain barrier-permeable
- Modulates GABAA and NMDA receptors
- Exhibits antioxidation and metabolic regulation
- Biomarker for renal function, muscle mass, and clinical outcomes
- Used for perioperative renal risk assessment
- Applied in research for neurodegenerative diseases, psychiatric disorders, and kidney diseases
Medchemexpress LLC Irbesartan | 200 MG
Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). It functions by relaxing the blood vessels, which in turn helps to lower blood pressure and increase the supply of blood and oxygen to the heart. This compound can be utilized for research purposes focusing on conditions such as high blood pressure, heart failure, and diabetic kidney disease.
- Orally active Ang II type 1 (AT1) receptor blocker (ARB)
- Relaxes blood vessels
- Lowers blood pressure
- Increases blood and oxygen supply to the heart
- Useful for research on high blood pressure
- Useful for research on heart failure
- Useful for research on diabetic kidney disease