Benzodioxoles

Aromatic organic heterocyclic compounds that consist of a benzene containing the methylenedioxy functional group; methylenedioxy functional groups have two oxygen atoms connected to a methylene bridge.

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331

Medchemexpress LLC (5E,9E,13E)-Teprenone | 3796-63-2 | 99.9% | 5 MG

(5E,9E,13E)-Teprenone is an isomer of Teprenone with antiulcer activity. It induces transcriptional activation of heat shock protein (HSP) genes, which may enhance gastric mucosal defense under stress conditions. In vitro studies suggest that it might transiently activate the transcription of the HSP70 gene. In vivo, it induces heat shock protein accumulations in rat gastric mucosa, including HSP90, HSP70, HSC70, and HSP60.

Exhibits antiulcer activity
Induces transcriptional activation of HSP genes
Enhances gastric mucosal defense under stress conditions
Activates heat shock factor 1
Causes accumulation of various heat shock proteins in rat gastric mucosa

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332

Medchemexpress LLC 10,11-(Methylenedioxy)-20(S)-camptothecin | 135415-73-5 | 99.4% | 392.36 | C21H16N2O6 | 5MG

FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin) is a camptothecin analogue research compound that functions as a potent survivin inhibitor with reported oral activity in preclinical studies. It acts as a molecular glue degrader of DDX5 (p68), promoting dephosphorylation and degradation of oncogenic proteins, and is provided as a high-purity material for in vitro and in vivo cancer research.

Has potent survivin inhibition and demonstrated antitumor activity.
Acts as a molecular glue degrader targeting DDX5 to modulate oncogenic pathways.
Suitable for both in vitro and in vivo cancer research applications.
Provided at high purity to support experimental reproducibility.
Available in small-mass packages appropriate for preclinical studies.
Molecular weight 392.36 and formula C21H16N2O6 for accurate dosing calculations.