Benzoxazines
![Aat Bioquest Beta-trifluoromethylumbelliferone [7-Hydroxy-4-trifluoromethylcoumarin] [CAS 575-03-1]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Aat Bioquest Beta-trifluoromethylumbelliferone [7-Hydroxy-4-trifluoromethylcoumarin] [CAS 575-03-1]
This coumarin compound is used as a calibration standard for 7-hydroxy-4-trifluoromethylcoumarin-based enzyme substrates.
Aat Bioquest AMC [7-Amino-4-methylcoumarin] [CAS 26093-31-2]
This compound is the precursor for a variety of AMC enzyme substrates.
TARGETMOL CHEMICALS INC GSK3787 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK3787 is a specific and irreversible PPAR(delta) inhibitor（pIC50= 6.6）. purity: 98%
TARGETMOL CHEMICALS INC DARGLITAZONE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Darglitazone (CP-86325) is a potent selective agonist of PPAR-(gamma) with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism. purity: 99%
TARGETMOL CHEMICALS INC MCUF-651 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators EC50=0.45 uM. purity: 99%
AdipoGen Resorufin ethyl ether
Chemical. CAS 5725-91-7. Formula C14H11NO3. MW 241.24. Synthetic. Dealkylase substrate for the microfluorimetric analysis of microsomal cytochrome P-450.
TARGETMOL CHEMICALS INC MOSLOFLAVONE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-(alpha) and IL-1(beta) with IC50 values of 0.71 uM and 7.8 uM respectively. purity: 98%
TARGETMOL CHEMICALS INC QN523 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. QN523 represents a novel scaffold with drug-like properties showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 shows significant in vivo efficacy in a pancreatic cancer xenograft model. Autophagy is a major mechanism of action. purity: 97%
TARGETMOL CHEMICALS INC ALTENUSIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Altenusin is a natural nonsteroidal fungal metabolite as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 uM. purity: 98%
TARGETMOL CHEMICALS INC EGFR-IN-12 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50 21 nM) and blocks receptor autophosphorylation in cells. purity: 99%
TARGETMOL CHEMICALS INC LOUREIRIN A 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of (alpha)- SMATGF- (beta)1and the proliferation of HSCs. purity: 99%
TARGETMOL CHEMICALS INC CEAPIN-A7 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ceapin-A7 is a selective blocker of ATF6(alpha) signaling in response to ER stress with an IC50 of 0.59 uM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6(alpha) and its role in pathological settings. purity: 99%
TARGETMOL CHEMICALS INC STM2457 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. STM2457 is a first-in-class highly potent selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML). purity: 99%