Benzoxazines
TARGETMOL CHEMICALS INC QN523 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. QN523 represents a novel scaffold with drug-like properties showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 shows significant in vivo efficacy in a pancreatic cancer xenograft model. Autophagy is a major mechanism of action. purity: 97%
TARGETMOL CHEMICALS INC CAY10602 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-dependently suppresses the NF-(kappa)B-dependent induction of TNF-(alpha) by lipopolysaccharide in THP-1 cells with approximately 75% inhibition achieved at 60 uM without cytotoxicity. purity: 98%
Cell Signaling Technology Acetyl-alpha-Tubulin (Lys40) (D20G3) XP(R) Rabbit mAb (Alexa Fluor(R) 750 Conjugate) 100 ul
Acetyl-alpha-Tubulin (Lys40) (D20G3) XP(R) Rabbit mAb (Alexa Fluor(R) 750 Conjugate) 100 ul
TARGETMOL CHEMICALS INC SQ22536 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) the adenosine analogue 9-(Tetrahydro-2-furyl)adenine inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isolated hepatocytes in a non-competitive manner. purity: 98%
Cell Signaling Technology IL-18 (E3G8R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
IL-18 (E3G8R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
Cell Signaling Technology Phospho-NF-kappa-B p65 (Ser536) (93H1) Rabbit mAb (Alexa Fluor(R) 700 Conjugate) 100 ul
Phospho-NF-kappa-B p65 (Ser536) (93H1) Rabbit mAb (Alexa Fluor(R) 700 Conjugate) 100 ul
TARGETMOL CHEMICALS INC VERAPAMIL 200MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure heart arrhythmias and angina research. purity: 99%
TARGETMOL CHEMICALS INC GSK572A 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK572A is a novel and potent potent inhibitor of EchA6 which can be used to treat tuberculosis. purity: 98%
Cell Signaling Technology ZO-1 (D6L1E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate) 100 ul
ZO-1 (D6L1E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate) 100 ul
Cell Signaling Technology CD3 (UCHT1) Mouse mAb (FITC Conjugate) 500 ul
CD3 (UCHT1) Mouse mAb (FITC Conjugate) 500 ul
Cell Signaling Technology PRAME E7I1B Rabbit mAb Alex
PRAME (E7I1B) Rabbit mAb (Alexa Fluor(R) 488 Conjugate) 100 ul
TARGETMOL CHEMICALS INC RAFABEGRON 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Rafabegron (TAK677) is a potent and selective (beta)3 adrenergic receptor agonist for the study of diabetes and obesity. purity: 100%
TARGETMOL CHEMICALS INC DCZ3301 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DCZ3301 is a novel aryl-guanidino inhibitor. purity: 99%
TARGETMOL CHEMICALS INC DRB 100MG
Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 uM)purity: 99%
TARGETMOL CHEMICALS INC HMAO-B-IN-4 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. hMAO-B-IN-4 is a selective reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B IC50=0.067 uM Ki= 0.03 uM hMAO-A IC50= 33.82 uM). purity: 99%