Benzoxazines
TARGETMOL CHEMICALS INC PIM1/AKK1-IN-1 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively and also inhibits MPSK1 and TNIK. purity: 98%
TARGETMOL CHEMICALS INC GLECAPREVIR 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor (IC50s 3.5-11.3 nM). purity: 99%
TARGETMOL CHEMICALS INC AMG-458 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM ~350-fold selectivity for c-Met than VEGFR2 in cells. purity: 99%
TARGETMOL CHEMICALS INC ZY-19489 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA. purity: 98%
TARGETMOL CHEMICALS INC AVACOPAN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. purity: 99%
