Benzoxazines
Kyfora Bio Beta-sitostanol 5 MG
β-Sitostanol is a saturated plant sterol belonging to the same family as campesterol and β-sitosterol. This compound is structurally similar to cholesterol and is known to integrate into lipid bilayers, affecting membrane fluidity and function. β-Sitostanol is widely used in scientific research applications, including the formulation of micelles and liposomes. It serves as a valuable tool in cell culture studies for investigating cellular uptake mechanisms, lipid metabolism, and cholesterol absorption.Applications: Micelle formulation, cell culture studies, cellular uptake monitoring
Kyfora Bio DSTAP 500 MG
DSTAP chloride (1,2-distearoyl-3-trimethylammonium-propane chloride) is a cationic lipid and a with a variety of potential applications, including transfection and drug delivery.
Kyfora Bio DMTAP 100 MG
DMTAP Chloride (1,2-dimyristoyl-3-trimethylammonium-propane chloride) is a cationic lipid and an analogue of DOTAP. It can be used to formulate lipid nanoparticles (LNPs) and lipid nanodiscs for the delivery nucleic acids, such as siRNA as well as for magnetic cationic liposomes for targeting tumor microvasculature. Key application(s): Drug delivery, nucleic acid delivery
AdipoGen ZnAF-1F Solution
Chemical. CAS 443302-08-7. Formula C34H26F2N4O5. MW 608.59. Synthetic. ZnAF-1F and ZnAF-2F do not fluoresce in the presence of other biologically important cations such as Ca2 and Mg2, and are insensitive to change of pH. The complexes with Zn2 of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2 complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence under neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. Spectral data lambdaex 492nm lambdaem 517nm in PBS.
AdipoGen ZnAF-2 DA Solution
Chemical. CAS 357339-96-9. Formula C38H32N4O7. MW 656.68. Synthetic. Suitable for the fluorimetric detection of Zn2 after esterase hydrolysis. Spectral data lambdaex 492nm lambdaem 515nm in PBS.
AdipoGen ZnAF-1F
Chemical. CAS 443302-08-7. Formula C34H26F2N4O5. MW 608.59. Synthetic. ZnAF-1F and ZnAF-2F do not fluoresce in the presence of other biologically important cations such as Ca2 and Mg2, and are insensitive to change of pH. The complexes with Zn2 of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2 complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence under neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. Spectral data lambdaex 492nm lambdaem 517nm in PBS.
AdipoGen 56-CFDA
Chemical. CAS 124387-19-5. Formula C25H16O9. MW 460.39. Synthetic. CFDA is a popular, sensitive, fluorescent substrate for measuring esterase activity in live cells. It is often used in cell viability assays and "Live-Dead" assay systems, especially automated cell viability assays. The cleavage product produced upon enzymatic or chemical hydrolysis of the acetate groups is carboxyfluorescein which is well-retained inside live cells, while the substrate CFDA is membrane permeant.
AdipoGen Carboxy-DCF
Chemical. CAS 111843-78-8. Formula C21H10Cl2O7. MW 445.21. Synthetic. Fluorescent intracellular pH indicator in the pH 4-5 range.
AdipoGen 6-FAM
Chemical. CAS 3301-79-9. Formula C21H12O7. MW 376.32. Synthetic. The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells pH ~6.8-7.4. Carboxyfluorescein is commonly employed as a polar tracer.
AdipoGen Benzylamino-NBD
Chemical. CAS 18378-20-6. Formula C13H10N4O3. MW 270.2. 4-Benzylamino-7-nitrobenzofurazan is a fluorescent probe. It exhibits absorption and emission bands that are sensitive to solvent polarity, and is used as fluorescent probes in the study of micellar and lipid bilayer structures. Shorter fluorescence lifetimes are observed with more polar solvents, making the probes suited for studies of binary solvent systems. Spectral Data lambdaEx/lambdaEm EtOH = 460/540nm.
AdipoGen 56-ROX
Chemical. CAS 198978-94-8. Formula C33H30N2O5. MW 534.6. Synthetic. May be used as a fluorescent dye in nucleic acid analytical research applications.
AdipoGen 5-ROX
Chemical. CAS 216699-35-3. Formula C33H30N2O5. MW 534.6. Synthetic. 5-ROX is the purified isomer of 56-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates. Used for oligonucleotide labeling and automated DNA sequencing applications.
AdipoGen Benzylamino-NBD
Chemical. CAS 18378-20-6. Formula C13H10N4O3. MW 270.2. 4-Benzylamino-7-nitrobenzofurazan is a fluorescent probe. It exhibits absorption and emission bands that are sensitive to solvent polarity, and is used as fluorescent probes in the study of micellar and lipid bilayer structures. Shorter fluorescence lifetimes are observed with more polar solvents, making the probes suited for studies of binary solvent systems. Spectral Data lambdaEx/lambdaEm EtOH = 460/540nm.
AdipoGen BHHT
Chemical. CAS 200862-69-7. Formula C30H16F14O4. MW 706.42. Synthetic. Chelating label for europium Eu3. Builds luminescent complexes that can be directly bound to proteins and detected.
AdipoGen Biotin-5-fluorescein-conjugate
Chemical. CAS 957494-27-8. Formula C33H32N4O8S. MW 644.7. Synthetic. Biotin-fluorescein conjugate for the fluorometric accurate measurement and quantification of avidin and streptavidin. Shows exceptionally fast and tight binding to avidin and streptavidin accompanied by strong quenching. Used in spectrophotometric streptavidin-biotin binding assays. May be used in situations similar to fluorescein isothiocyanate staining to label avidin/streptavidin conjugated molecules such as antibodies with the fluorophore 5-fluorescein. Spectral Data lambdaex 490nm lambdaem 524nm in 0.1M Tris pH8.0.