Biotin and derivatives
Medchemexpress LLC m-PEG14-NHS ester | 95.0% | 773.86 | 25 MG
m-PEG14-NHS ester is a PEG-based PROTAC linker. This chemical is intended for laboratory use in the synthesis of PROTACs.
- Supplied as a white to off-white solid
- Stable under recommended storage conditions
- Recommended storage at -20°C, sealed storage, away from moisture and light
- Shipping at room temperature if less than 2 weeks
- Has a purity of 95.0%
- Molecular weight is 773.86
![Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000280727.png-250.jpg)
Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable azido-PEG3 NHS carbonate linker for labeling primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It combines an NHS carbonate reactive group with an azide handle and a photocleavable moiety to enable covalent labeling and light-triggered release. Supplied as a colorless to light-yellow oil for research use; follow manufacturer storage recommendations.
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 1 G
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It also functions as a PEG- and Alkyl/ether based PROTAC linker for synthesizing PROTACs. This compound is a click chemistry reagent, featuring an Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Cleavable linker
- PEG linker type
- Alkyl/ether linker type
- Click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Used in ADC synthesis
- Used in PROTAC synthesis
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-NHS (DSPE-NHS) | 1383932-86-2 | MFCD34561791 | 95.0% | 945.2 g/mol | C49H89N2O13P | 10 MG
DSPE-NHS is an N-hydroxysuccinimide (NHS) ester functionalized distearoyl phosphoethanolamine used for bioconjugation and liposome formation. The reagent self-assembles into lipid bilayers in aqueous solution, and the NHS ester reacts selectively with primary amines to form stable amide bonds, enabling antibody labeling and attachment of amine-containing molecules for nanoparticle and drug-delivery applications.
- Reactive NHS ester for covalent coupling to primary amines.
- Self-assembles into lipid bilayers in aqueous solution.
- Enables antibody labeling and protein conjugation.
- Suitable for liposome and nanocarrier preparation.
- Long-term storage recommended at -20 °C, sealed and protected from moisture and light.
Medchemexpress LLC Biotin-EDA | 111790-37-5 | 97.5% | 250 MG
Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are molecules that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker: one ligand for an E3 ubiquitin ligase and the other for the target protein.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of two different ligands connected by a linker
- White to off-white solid appearance
eMolecules Hydroxy-PEG11-t-butyl ester | BroadpharmMFCD29049421 | 630.769 | C29H58O14 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 490840967
Hydroxy-PEG11-t-butyl ester | BroadpharmMFCD29049421 | 630.769 | C29H58O14 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 490840967
eMolecules 58-85-5 | D-(+)-Biotin | Apollo Scientific US | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
D-(+)-Biotin | Apollo Scientific US | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
Medchemexpress LLC (+)-Biotin 4-nitrophenyl ester | 33755-53-2 | ≥98.0% | 250 MG
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | ≥97.0% | 501.49 | C20H31N5O10 | 5 G
DOTA-NHS-ester is an N-hydroxysuccinimide ester derivative of the DOTA chelator used to conjugate amine-containing molecules for radiolabeling and imaging probe development. It is supplied as a solid and is handled and stored under low-temperature, moisture-free conditions.
- Used to conjugate DOTA to primary amines for PET and SPECT probe development.
- High purity suitable for research applications.
- Soluble in DMSO at 50 mg/mL; protocols provided for aqueous in vivo formulations.
- Stable as a solid when stored sealed at -20 °C; dissolved samples have recommended cold storage times.
- Molecular weight 501.49 and CAS number 170908-81-3 for unambiguous identification.
Medchemexpress LLC m-PEG-NHS ester | 92451-01-9 | MFCD06412227 | 90.0% | 350 g/mol | (C2H4O)nC7H9NO5 | 10 MG
m-PEG-NHS ester (MW 350) is a methoxy-terminated polyethylene glycol activated as an N-hydroxysuccinimide (NHS) ester for covalent PEGylation of primary amine-containing molecules. It is intended to improve solubility and stability, reduce immunogenicity, and enable bioconjugation and surface functionalization in research applications.
- Activated NHS ester for efficient coupling to primary amines.
- Methoxy termination prevents crosslinking and limits multi-attachment.
- Improves solubility and stability of biomolecules.
- Reduces immunogenicity and can extend circulation half-life.
- Suitable for protein, peptide, and small-molecule PEGylation.
- Available in small mg-scale quantities for research use.
Medchemexpress LLC exo-BCN-NHS carbonat 25mg
exo-BCN-NHS carbonate carbonate contains BCN group Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 1 MG
FP-biotin is a potent organophosphorus toxicant, ideal for identifying new biomarkers of organophosphorus toxicants exposure. It quantifies the activity of FAAH, ABHD6, and MAG-lipase. This product is utilized in plasma studies because biotinylated peptides can be easily purified by binding to immobilized avidin beads. It is suitable for identifying organophosphorus toxicants reactive proteins and is for research use only.
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Used in plasma studies for easy purification of biotinylated peptides
- Suitable for identifying organophosphorus toxicants reactive proteins
- Appears as a white to light yellow solid
- Ships at room temperature in continental US
- Store at -20°C under nitrogen; in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Soluble in DMSO (25 mg/mL)
Medchemexpress LLC Endo-BCN-NHS carbonate | 1426827-79-3 | MFCD19705416 | ≥97.0% | 291.30 g·mol⁻1 | C15H17NO5 | 500 MG
endo-BCN-NHS carbonate is an NHS-activated bicyclo[6.1.0]non-4-yne (BCN) carbonate reagent for bioconjugation. It couples to primary amines to install a strained cyclooctyne handle for strain-promoted azide-alkyne cycloaddition (SPAAC), enabling copper-free bioorthogonal labeling of proteins, peptides, and polymers.
- NHS-activated carbonate enables efficient coupling to primary amines.
- Introduces a strained BCN handle for copper-free SPAAC reactions.
- High purity suitable for analytical and preparative bioconjugation.
- Solid form with recommended storage at -20°C for prolonged stability.
- Compatible with proteins, peptides, and polymer modification workflows.
Chem-Impex International, Inc. Biotin p-nitrophenyl ester | MFCD15141972 | 250MG
Biotin p-nitrophenyl ester, MFCD15141972, 250MG