Biotin and derivatives
Medchemexpress LLC AF647-NHS ester (triTEA) | 407627-61-6 | 99.7% | 10 MG
AF647-NHS ester (triTEA) is a far-red fluorescent NHS ester reagent used to label primary amines for fluorescence detection. Supplied as a purple solid, it is optimized for conventional and instantaneous detection and is soluble in DMSO when warmed or sonicated.
- Far-red fluorescent NHS ester for amine conjugation.
- Excitation: 635 nm (conventional) / 620 nm (instantaneous).
- Physical form: purple to dark purple solid.
- Purity: 99.74% as reported by manufacturer.
- Solubility: DMSO 20 mg/mL; use freshly opened DMSO and apply ultrasonic/heat to 60°C as needed.
- Storage: protect from light and store under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for patient use.
Medchemexpress LLC N-succinimidyl-3-(2-pyridyldithio)butyrate | 107348-47-0 | MFCD28398150 | 98.3% | 326.4 g/mol | C13H14N2O4S2 | 1 G
PPC-NHS ester (N-succinimidyl-3-(2-pyridyldithio)butyrate, CAS 107348-47-0) is an NHS-activated cleavable linker reagent used for conjugating small molecules to proteins and antibodies. It reacts with primary amines to form stable amide bonds and contains a pyridyldisulfide moiety that enables controlled cleavage under reducing conditions, making it suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Reacts with primary amines to form stable amide bonds.
- Contains a pyridyldisulfide cleavable linkage for controlled release under reducing conditions.
- High purity suitable for conjugation workflows (≈98.3%).
- Compatible with common aqueous and organic conjugation conditions.
Medchemexpress LLC exo-BCN-NHS carbonat 25mg
exo-BCN-NHS carbonate carbonate contains BCN group Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups
![Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl] | 188682-72-6 | MFCD00213997 | 99.9% | 533.68 g·mol⁻¹ | C26H39N5O5S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288114.png-250.jpg)
Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl] | 188682-72-6 | MFCD00213997 | 99.9% | 533.68 g·mol⁻¹ | C26H39N5O5S | 10 MG
Biotin-BMCC is a maleimide-activated biotinylation reagent that reacts selectively with free thiol groups of cysteines to install a biotin tag for detection, affinity capture, or purification of proteins and peptides.
- Reacts selectively with free thiol groups (cysteines).
- Introduces a biotin handle compatible with streptavidin/avidin affinity methods.
- High chemical purity (99.9%).
- Suitable for labeling proteins and peptides for detection and affinity purification.
Medchemexpress LLC PD-L2 Human Biotin 20ug
PD-L2 Protein operating independently of PDCD1 plays a vital role in T-cell proliferation and IFNG production Its interaction with PDCD1 inhibits proliferation and cytokine production The interplay between PD-L2 and PDCD1 regulates immune responses influencing T-cell activation and function This molecular interaction adds complexity to mechanisms governing T-cell behavior highlighting PD-L2 s versatile role in immune regulation PD-L2 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived PD-L2 protein expressed by HEK293 with C-Avi C-6 His labeled tag
Medchemexpress LLC B7-H4 Human Biotin 100ug | 100ug
The B7-H4 protein acts as a negative regulator inhibiting T cell-mediated immune responses including activation proliferation cytokine production and cytotoxicity When expressed on tumor macrophages it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity B7-H4 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived B7-H4 protein expressed by HEK293 with C-Avi C-His labeled tag
Medchemexpress LLC Biotin-C10-NHS ester | 887628-40-2 | MFCD05865045 | 99.5% | 524.67 | C25H40N4O6S | 5 MG
Biotin-C10-NHS ester is an alkyl/ether-based PROTAC linker bearing an N-hydroxysuccinimide (NHS) ester and a ten-carbon biotin spacer. It reacts with primary amines to install a biotin handle for affinity capture, target identification, and PROTAC probe construction. The compound is supplied as a solid with reported high purity and recommended low-temperature storage to maintain stability.
- Alkyl/ether-based PROTAC linker suited for probe design.
- NHS ester for efficient coupling to primary amines.
- Ten-carbon biotin spacer for robust affinity capture.
- Supplied as a solid with reported high purity.
- Storage conditions preserve stability (powder -20°C).
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa
Medchemexpress LLC PD-L1 Mouse Biotin 100ug | 100ug
PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance This interaction modulates T cell activation limits effector responses and may stimulate IL10-producing T cell subsets PD-L1 Protein Mouse (Biotinylated HEK293 His) is the recombinant mouse-derived PD-L1 protein expressed by HEK293 with C-His labeled tag