Biotin and derivatives
Medchemexpress LLC Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate | 00-00-0 | 98.0% | C38H66F3N13O11S | 10MG
Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate is an azide-containing biotinylated reagent for click chemistry labeling of proteins. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) to conjugate with alkyne-bearing probes, enabling detection of protein modification sites. Intended for research use.
- Contains an azide group for CuAAC and SPAAC reactions.
- Biotin tag enables affinity detection and signal amplification.
- PEG3 linker provides hydrophilicity and spacer flexibility.
- High purity (98.0%) suitable for labeling applications.
- White to off-white solid with recommended handling precautions.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at -20°C; in solvent store at -80°C for long-term stability.
Medchemexpress LLC Cyanine5.5 NHS ester (tetrafluoroborate) | 2375105-86-3 | 98.4% | 767.66 | 10 MG
Cyanine5.5 NHS ester tetrafluoroborate is a member of the cyanine dye series, serving as a common fluorescent marker for biomolecules. It can interact with biomolecules and may also bind to double-helical DNA through intercalation, exhibiting enhanced fluorescence upon binding.
- Common fluorescent marker for biomolecules
- Interacts with biomolecules
- May bind to double-helical DNA through intercalation
- Exhibits enhanced fluorescence upon binding to DNA
- For research use only
- In vitro protocols available for protein preparation, dye preparation, dosage calculation, conjugation reactions, and purification
![Medchemexpress LLC N-(4-aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | 151294-96-1 | MFCD28397129 | 97.0% | 314.45 g/mol | C14H26N4O2S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203872.png-250.jpg)
Medchemexpress LLC N-(4-aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | 151294-96-1 | MFCD28397129 | 97.0% | 314.45 g/mol | C14H26N4O2S | 50 MG
Biotin-C4-amide-C5-NH2 is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin tag and a primary amine for affinity capture and conjugation during ADC synthesis and analysis. Intended for research use only.
- Cleavable ADC linker with biotin tag for affinity-based capture.
- Primary amine enables conjugation to payloads or linkers.
- High purity: 97.0% (typical).
- Molecular weight 314.45 g/mol; formula C14H26N4O2S.
- Storage: store at 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human therapeutic use.
Medchemexpress LLC Af647-nhs ester tritea | 407627-61-6 | 99.7% | 1259.66 | 5 MG
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647) with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection) / 620 nm (instantaneous detection). The NHS ester can covalently bind to molecules with amino groups, such as proteins and antibodies.
- Analogue of Alexa Fluor 647 (AF647)
- Excitation wavelength (λex) of 635 nm (conventional fluorescence detection) / 620 nm (instantaneous detection)
- NHS ester can covalently bind to molecules with amino groups (e.g., proteins, antibodies)
![eMolecules 1738-86-9 | Z-Gly-ONp | Combi-Blocks | MFCD00024663 | 330.296 | C16H14N2O6 | 97.000 | [O-][N+](=O)c1ccc(OC(=O)CNC(=O)OCc2ccccc2)cc1 | 1g | 335350486](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502186022.JPG-250.jpg)
eMolecules 1738-86-9 | Z-Gly-ONp | Combi-Blocks | MFCD00024663 | 330.296 | C16H14N2O6 | 97.000 | [O-][N+](=O)c1ccc(OC(=O)CNC(=O)OCc2ccccc2)cc1 | 1g | 335350486
Z-Gly-ONp | Combi-Blocks | 1738-86-9 | MFCD00024663 | 330.296 | C16H14N2O6 | 97.000 | [O-][N+](=O)c1ccc(OC(=O)CNC(=O)OCc2ccccc2)cc1 | 1g | 335350486
Medchemexpress LLC Alexa fluor 647 NHS ester | 1620475-28-6 | 95.0% | 942.06 | 5 MG
Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. It is for research use only and not sold to patients.
- Used to label primary amines
- Suitable for proteins, amine-modified oligonucleotides, and other amine-containing molecules
- For research use only
Medchemexpress LLC Cyanine5.5 NHS ester (tetrafluoroborate) | 2375105-86-3 | 767.66 | 5 MG
Cyanine5.5 NHS ester tetrafluoroborate is a member of the cyanine dye series, serving as a common fluorescent marker for biomolecules. It can interact with biomolecules and may bind to double-helical DNA through intercalation, exhibiting enhanced fluorescence upon binding.
- Common fluorescent marker for biomolecules.
- Interacts with biomolecules.
- Binds to double-helical DNA through intercalation, exhibiting enhanced fluorescence.
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | >98.7% | 456.41 | 100 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. It is for research use only and not sold to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide-based cereblon ligand and NHS ester linker
- Targets cereblon
eMolecules 2231747-18-3 | Medchem Express | N-piperidine Ibrutinib (hydrochloride) | 5mg | 600899891 | HY-130983 | 422.92 | C22H23ClN6O
Ambeed | 4-(Diphenylphosphino)benzaldehyde | 100mg | 633419231 | A844008 | 5068-18-8 | MFCD26743564 | 290.302 | C19H15OP
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Medchemexpress LLC Biotin-TEG-ATFBA | 1264662-85-2 | C27H37F4N7O6S | 5 MG
Biotin-TEG-ATFBA is a click chemistry reagent featuring a perfluorophenylazide group. It forms a stable azene intermediate that undergoes insertion and addition reactions with good yields after photolysis. The compound also contains an azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC).
- Contains a perfluorophenylazide group
- Forms a highly stable azene intermediate
- Undergoes insertion and addition reactions after photolysis
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Engages in ring strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Boc-N-PEG1-C2-NHS ester | 1260092-55-4 | 97.0% | C14H22N2O7 | 250 MG
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Selectively degrades target proteins
- Utilizes the intracellular ubiquitin-proteasome system
Medchemexpress LLC Biotin-PEG6-azide | 1085938-09-5 | 99.9% | C24H44N6O8S | 100 MG
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Biotin-labeled
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
- Designed for selective protein degradation via PROTACs
Medchemexpress LLC Mal-PEG6-NHS ester | 1599472-25-9 | MFCD20926374 | 98.0% | 530.52 g/mol | C23H34N2O12 | 1 G
Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a maleimide reactive group, a six-unit polyethylene glycol (PEG6) spacer, and an N-hydroxysuccinimide (NHS) ester for amine coupling. It is supplied for research use in synthesis and bioconjugation workflows.
- Purity 98.0%.
- Cas number 1599472-25-9.
- Molecular weight 530.52 g/mol.
- Chemical formula C23H34N2O12.
- Soluble in DMSO at 100 mg/mL (in vitro; ultrasonic recommended).
- Suggested in vivo formulations provided for dosing preparations.
- For research use only; not for use in patients.
- Pack quantity 1 G.
Medchemexpress LLC 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-Heneicosaoxaheptahexacontanedioic acid, 1,67-bis(2,5-dioxo-1-pyrrolidinyl) ester | 2221948-98-5 | 99.89% | 250 MG
Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker that can be utilized in the synthesis of PROTACs. It also serves as a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Can be used in the synthesis of PROTACs.
- Serves as a cleavable ADC linker.
Medchemexpress LLC Biotin-PEG-Biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 50 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system to degrade target proteins