Biotin and derivatives
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa
Medchemexpress LLC CA125 Human Biotin 50ug | 50ug
The CA125 protein acts by binding to MSLN and plays a crucial role in forming a protective and lubricating barrier on mucosal surfaces This interaction promotes heterotypic cell adhesion and is suggested to play an important role in peritoneal metastasis of ovarian cancer CA125 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived CA125 protein expressed by HEK293 with C-Avi C-His labeled tag
Medchemexpress LLC m-PEG8-NHS ester | 756525-90-3 | MFCD13184969 | 95.0% | 509.54 g/mol | C22H39NO12 | 100 MG
m-PEG8-NHS ester is a methoxy polyethylene glycol (PEG) linker containing an N-hydroxysuccinimide (NHS) ester functional group. It provides an eight-unit PEG spacer for conjugation to primary amines and is used in antibody-drug conjugate (ADC) synthesis and general bioconjugation to increase solubility and reduce aggregation.
- Non-cleavable 8-unit PEG spacer
- Amine-reactive NHS ester for conjugation
- Supplied as a 100 mg vial (research use only)
- Purity by NMR: 95.0%
- Molecular weight 509.54 g/mol; formula C22H39NO12
- Store pure material at -20°C for long-term stability
Medchemexpress LLC DBCO-N-bis(PEG4-NHS ester) | 2639395-38-1 | 96.2% | 995.03 | C49H62N4O18 | 5 MG
DBCO-N-bis(PEG4-NHS ester) is a PEG-based bifunctional linker that contains two PEG4-NHS ester groups and a dibenzocyclooctyne (DBCO) moiety. It is designed for bioconjugation and protein labeling via NHS-ester chemistry and for copper-free click conjugation with azide-containing partners through strain-promoted alkyne-azide cycloaddition (SPAAC).
- Contains two PEG4-NHS ester groups and a DBCO functional group.
- Enables protein modification through NHS-ester conjugation to primary amines.
- Supports copper-free SPAAC click chemistry with azide partners.
- Suitable for small-scale research use; available in 5 mg and larger sizes.
- Molecular weight 995.03; CAS number 2639395-38-1.
Medchemexpress LLC Biotin-lc-lc-nhs | 89889-52-1 | 98.0% | 567.70 | C26H41N5O7S | 25 MG
Biotin-LC-LC-NHS is an N-hydroxysuccinimide (NHS) ester biotinylation reagent with dual long-chain spacers. It covalently attaches biotin to primary amines on proteins, antibodies, and small molecules for labeling, detection, or affinity capture. Handle using appropriate safety precautions and store protected from light at -20°C.
- NHS ester reactive toward primary amines.
- Dual long-chain spacers reduce steric hindrance during labeling.
- Molecular weight 567.70 and formula C26H41N5O7S for precise calculations.
- Purity 98.0% for research-grade applications.
- High solubility in DMSO (100 mg/mL) with recommended freshly opened DMSO.
- Store at -20°C, protect from light, and handle under standard laboratory safety practices.
Medchemexpress LLC DBCO-NHS ester 2 100mg | 1384870-47-6 | 100 MG
DBCO-C6-NHS ester is a DBCO-derived N-hydroxysuccinimide (NHS) ester used to introduce a DBCO handle onto amine-containing molecules for copper-free, strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation and antibody-drug conjugate (ADC) linker synthesis.
- Amine-reactive NHS ester for covalent coupling to primary and secondary amines.
- Facilitates copper-free SPAAC click chemistry with azide-functionalized partners.
- Suitable for bioconjugation, ADC synthesis, and labeling of proteins or small molecules.
- Available in multiple sizes; typical laboratory scale is 100 mg.
- Soluble in DMSO (~14.29 mg/mL); store powder at -20°C for long-term stability.
Medchemexpress LLC Azido-PEG16-NHS ester | 00-00-0 | 99.9% | C39H72N4O20 | 10MG
Azido-PEG16-NHS ester is a PEG-based bifunctional linker featuring an azide moiety and an N-hydroxysuccinimide (NHS) ester. It enables conjugation to primary amines via the NHS ester and subsequent click chemistry using the azide, making it suitable for bioconjugation, labeling, and PROTAC synthesis. The reagent is provided at high purity and is soluble in DMSO for convenient formulation.
Medchemexpress LLC (S,E)-TCO-NHS ester | 1610931-22-0 | MFCD24386372 | ≥98.0% | 267.28 g/mol | C13H17NO5 | 10 MG
TCO-NHS ester (axial) is a trans-cyclooctene N-hydroxysuccinimide ester used as an amine-reactive building block for bioorthogonal conjugation. It enables rapid inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine partners and is suitable for labeling or modifying amine-containing small molecules and biomolecules in organic media. The reagent is supplied as a purified solid with supporting analytical documentation for research use.
- Amine-reactive NHS ester for efficient conjugation.
- Fast bioorthogonal iEDDA reactivity with tetrazines.
- Suitable for labeling and bioconjugation of biomolecules.
- High purity for reproducible experimental results.
- Analytical documentation available (SDS, COA, H-NMR).
Medchemexpress LLC NHS-SS-Ac | 2750799-11-0 | 95.0% | 337.37 | 25 MG
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid. It is intended for research use only.
- Amine-reactive product
- Purity of 95.0%
- Colorless to light yellow oil
- Recommended storage for pure form: -20°C for 3 years or 4°C for 2 years
- Soluble in DMSO (50 mg/mL)
Medchemexpress LLC Azido-PEG1-NHS ester | 1807530-06-8 | 99.78% | C9H12N4O5 | 25 MG
Azido-PEG1-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It serves as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Exploits the intracellular ubiquitin-proteasome system
- Selective degradation of target proteins
Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 250 MG
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker and a polyethylene glycol-containing bioconjugation reagent. It is utilized in scientific research for developing highly sensitive biosensors, targeted drug delivery systems, immunofluorescence imaging, and protein affinity purification, serving as a tool for precise biomolecule labeling and functionalization.
- Efficiently introduces biotin tags onto primary amine groups.
- Forms stable amide bonds under mild conditions.
- Incorporates a flexible spacer arm for increased molecular freedom.
- Enhances water solubility.
- Reduces non-specific adsorption.
Med Vet International Zoetis Simplicef Tablets, 200mg, 100ct.
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Simplicef (cefpodoxime proxetil) tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of Staphylococcus intermedius, Staphylococcus aureus, Streptococcus canis (group G, B hemolytic), Escherichia coli, Pasteurella multocida, and Proteus mirabilis.
Medchemexpress LLC Biotin-sar-oh | 154024-76-7 | 315.39 | C13H21N3O4S | 1 G
Biotin-sar-oh is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin functionality, used in the synthesis of antibody-drug conjugates and probe development.
- Cleavable ADC linker for conjugation and release strategies.
- Biotinylated for affinity capture and detection.
- Molecular formula: C13H21N3O4S; molecular weight: 315.39.
- Available pack sizes: 250 mg and 1 g.
- CAS number: 154024-76-7.
Medchemexpress LLC Ibrutinib-biotin | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 | C56H80N12O9S | 25 MG
Ibrutinib-biotin is a biotinylated probe in which the BTK inhibitor ibrutinib is linked to biotin via a long-chain linker (derived from patent WO2014059368A1 Compound 1-5). It is intended for research use to study Bruton's tyrosine kinase (BTK) binding, target engagement, and affinity-based assays.
- Biotinylated probe for affinity capture and target engagement studies.
- High potency against BTK with IC50 of 0.755-1.02 nM.
- High purity (99.66%) suitable for biochemical and cellular assays.
- Available in small quantities for assay development (25 mg).
- Includes downloadable datasheet, COA, and SDS for experimental reproducibility.