Biotin and derivatives
Medchemexpress LLC Bis-PEG30-NHS ester | 1633.81 | 5 MG
Bis-PEG30-NHS ester is a non-cleavable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is designed for various laboratory applications.
- Non-cleavable 30-unit PEG ADC linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
Medchemexpress LLC Mal-PEG1-NHS ester | 1807518-72-4 | 310.26 g/mol | C13H14N2O7 | 1 G
Mal-PEG1-NHS ester is a PEG-based bifunctional linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. It is used for bioconjugation in the synthesis of antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs), enabling selective thiol-to-amine coupling via maleimide and NHS chemistries.
- Bifunctional maleimide and NHS ester chemistry for thiol and amine coupling.
- PEG spacer increases solubility and reduces steric hindrance.
- Non-cleavable linker suitable for ADC and PROTAC synthesis.
- Available in multiple pack sizes, including 1 g for preparative use.
- Molecular weight 310.26 g/mol and formula C13H14N2O7.
eMolecules 756525-90-3 | M-PEG8-NHS ESTER | AstaTech | MFCD13184969 | 509.549 | C22H39NO12 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 1g | 624137097
M-PEG8-NHS ESTER | AstaTech | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 1g | 624137097
Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 50 MG
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Medchemexpress LLC PCSK9 Human Biotin 5ug | 5ug
The PCSK9 protein is an important regulator of plasma cholesterol homeostasis affecting LDL receptor family members such as LDLR and VLDLR It promotes their intracellular degradation and enhances hepatic LDLR degradation through non-proteolytic mechanisms PCSK9 Protein Human (Biotinylated HEK293 D374Y His-Avi) is the recombinant human-derived PCSK9 protein expressed by HEK293 with C-Avi C-His labeled tag and D374Y mutation
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 10 MM * 1 ML
FP-Biotin is a potent organophosphorus toxicant suitable for identifying new biomarkers of organophosphorus toxicant exposure. It quantifies the activity of FAAH, ABHD6, and MAG-lipase. It is used in plasma studies where biotinylated peptides can be easily purified by binding to immobilized avidin beads. FP-Biotin demonstrates good reactivity with human AChE and BChE and is suitable for identifying organophosphorus toxicants reactive proteins.
- Potent organophosphorus toxicant
- Suitable for identifying new biomarkers of organophosphorus toxicant exposure
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Useful in plasma studies for easy purification of biotinylated peptides
- Reacts well with human AChE and BChE
- Identifies organophosphorus toxicants reactive proteins
Medchemexpress LLC 4,7,10,13,16,19-hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-2,5-dioxo-1-pyrrolidinyl ester | 1599472-25-9 | 98.0% | 530.52 | C23H34N2O12 | 250 MG
Mal-PEG6-NHS ester is a noncleavable ADC linker that combines a thiol-reactive maleimide, a six-unit polyethylene glycol spacer, and an amine-reactive N-hydroxysuccinimide (NHS) ester. It is supplied for research conjugation applications and is formulated as a colorless to light yellow liquid.
- Noncleavable linker with maleimide and NHS reactive groups.
- Six-unit PEG spacer increases hydrophilicity and solubility.
- High purity (98.0%) suitable for research conjugation.
- Molecular weight approximately 530.52 daltons.
- Soluble in DMSO (100 mg/mL); ultrasonic assistance recommended.
- Store protected from light at -20°C; in solvent store at -80°C for long-term.
Research Products International Corp D Biotin 5 G
CAS Number: 58-85-5
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.3
Sigma Aldrich Fine Chemicals Biosciences Biotin meets USP testing specifications | 58-85-5 | MFCD00005541 | 500MG
Biotin meets USP testing specifications | Purity: 97.5-102.0% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 500MG
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | 99.89% | C33H56N4O14S | 50 MG
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. The product is intended for research use only.
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Intended for research use only
Medchemexpress LLC DBCO-PEG3-NHS ester | 2163772-16-3 | 98.5% | 605.64 g/mol | C32H35N3O9 | 10 MG
DBCO-PEG3-NHS ester is a PEG-spaced dibenzocyclooctyne (DBCO) reagent bearing an N-hydroxysuccinimide (NHS) ester. It is designed for copper-free click conjugation of azide-functionalized payloads to primary amines and is commonly used as a linker in bioconjugation workflows such as antibody-drug conjugate synthesis.
- Enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners.
- Contains an NHS ester reactive toward primary amines for facile conjugation.
- Peg3 spacer improves solubility and reduces steric hindrance at the conjugation site.
- Suitable for bioconjugation workflows, including linker installation for antibody-drug conjugates.
- Provided at high reported purity for reproducible conjugation performance.
Medchemexpress LLC Amine-PEG3-Biotin | 359860-27-8 | 99.8% | 418.55 | 10 MG
Amine-PEG3-Biotin is a signal amplification label that contains a biotin group and a terminal primary amine group. It is for research use only.
- Signal amplification label
- Contains a biotin group
- Contains a terminal primary amine group
- For research use only
Medchemexpress LLC Biotin LC hydrazide | 109276-34-8 | MFCD00077659 | 99.8% | 371.50 g/mol | C16H29N5O3S | 25 MG
Biotin LC hydrazide is a long-chain biotinylation reagent that reacts with aldehyde groups generated by periodate oxidation of glycoproteins, enabling selective labeling of carbohydrate-containing biomolecules for detection and affinity capture.
- Reacts with periodate-oxidized glycoproteins for selective carbohydrate labeling.
- Provides a long spacer arm to reduce steric hindrance in conjugation.
- Enables affinity purification and detection via biotin-streptavidin interactions.
- Solid powder stable when stored protected from light at 4°C; in solvent, store frozen for extended stability.
- High chemical purity supports reproducible conjugation performance.
Medchemexpress LLC Azido-PEG5-NHS ester | 1433996-86-1 | ≥98.0% | C17H28N4O9 | 25 MG
Azido-PEG5-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in the synthesis of PROTACs.
Medchemexpress LLC Biotin-PEG11-amine | 1418022-42-0 | 99.85% | C34H66N4O13S | 50 MG
Biotin-PEG11-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins