Biotin and derivatives
Medchemexpress LLC PD-L1 Mouse Biotin 100ug | 100ug
PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance This interaction modulates T cell activation limits effector responses and may stimulate IL10-producing T cell subsets PD-L1 Protein Mouse (Biotinylated HEK293 His) is the recombinant mouse-derived PD-L1 protein expressed by HEK293 with C-His labeled tag
![eMolecules 58-85-5 | D-Biotin | Chemodex Ltd. | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 482921470](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471147.jpg-250.jpg)
eMolecules 58-85-5 | D-Biotin | Chemodex Ltd. | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 482921470
D-Biotin | Chemodex Ltd. | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 482921470
Medchemexpress LLC Biotin-PEG-Biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 50 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system to degrade target proteins
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 25 MG
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. It quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is also used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads. In vitro, it shows good reactivity with human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), making it appropriate for identifying organophosphorus toxicants reactive proteins.
- Potent organophosphorus toxicant
- Suitable for identifying new biomarkers of organophosphorus toxicant exposure
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Used in plasma studies for easy purification of biotinylated peptides
- Exhibits good reactivity with human AChE and BChE
- Appropriate for identifying organophosphorus toxicant-reactive proteins
eMolecules 55750-61-3 | A-MALEIMIDOACETIC ACID-NHS(AMAS) | AstaTech | MFCD00133523 | 252.182 | C10H8N2O6 | 97.000 | O=C(CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 25g | 881785810
A-MALEIMIDOACETIC ACID-NHS(AMAS) | AstaTech | 55750-61-3 | MFCD00133523 | 252.182 | C10H8N2O6 | 97.000 | O=C(CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 25g | 881785810
![Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203007.png-250.jpg)
Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG
Bis-PEG2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester reactive groups at both ends, designed for antibody-agent conjugation via amine-coupling chemistry for research use.
- Noncleavable two-unit PEG linker for antibody-agent conjugation.
- N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling.
- High purity, 99.2%.
- Molecular weight 400.34 g/mol.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation may be required.
- Storage: powder at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple pack sizes, including 250 MG.
Medchemexpress LLC Biotin-TAT (47-57) | 1231898-25-1 | 98.56% | 1786.12 | 5 MG
Biotin-TAT (47-57) is a biotin-tagged transactivator of transcription (TAT). It is recognized as one of the most widely used protein transduction domains (PTDs). Its entry into different primary cells is ATP- and temperature-dependent, suggesting involvement of endocytosis. It is intended for research use only.
- Acts as a transactivator of transcription
- Widely used protein transduction domain
- Cellular uptake is ATP- and temperature-dependent
- Intended for research use only
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 | 25 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. This product is for research use only and not sold to patients.
- Incorporates Pomalidomide based cereblon ligand
- Includes NHS ester linker
- Targets Cereblon
- Soluble in DMSO at 100 mg/mL
![Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 1G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238902.png-250.jpg)
Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 1G
Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate is an alkyl/ether-based PROTAC linker containing an N-hydroxysuccinimide (NHS) ester for amine coupling and a pyridyldisulfide moiety for thiol-directed conjugation. It is used in PROTAC and bioconjugation synthesis and features a reducible disulfide that enables controlled cleavage in downstream applications.
- Provides an NHS ester for efficient conjugation to primary amines.
- Contains a pyridyldisulfide cleavable disulfide for thiol chemistry.
- Suitable as a linker in PROTAC and bioconjugation synthesis.
- Molecular formula C18H23N3O5S2; molecular weight 425.52 g/mol.
- Soluble in DMSO at approximately 50 mg/mL; may require sonication.
- Store powder at -20°C for long-term stability; solvent solutions require low-temperature storage.
- High purity (98.1%) suitable for research applications.
Medchemexpress LLC Sulfo-TAG NHS ester (disodium) | 482618-42-8 | 88.4% | 1185.12 g/mol | C43H39N7Na2O16RuS4 | 1 MG
Sulfo-TAG NHS ester (disodium) is a water-soluble N-hydroxysuccinimide (NHS) ester reagent for covalent labeling of proteins and antibodies via primary amine groups. The reagent contains a ruthenium-based electrochemiluminescent tag that enables sensitive electrochemiluminescence (ECL) detection when conjugated to antibodies. Supplied as a solid for research use; handle and store according to the supplier's SDS and COA.
- Couples to primary amine groups on proteins and antibodies for stable conjugation.
- Enables electrochemiluminescence (ECL) detection when attached to antibodies.
- Water-soluble formulation suitable for aqueous conjugation reactions.
- Provided with storage recommendations to maintain stability.
- Supplied with certificate of analysis (COA) and safety data sheet (SDS) specifying purity and molecular data.
Medchemexpress LLC PD-L2 Human Biotin 20ug
PD-L2 Protein operating independently of PDCD1 plays a vital role in T-cell proliferation and IFNG production Its interaction with PDCD1 inhibits proliferation and cytokine production The interplay between PD-L2 and PDCD1 regulates immune responses influencing T-cell activation and function This molecular interaction adds complexity to mechanisms governing T-cell behavior highlighting PD-L2 s versatile role in immune regulation PD-L2 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived PD-L2 protein expressed by HEK293 with C-Avi C-6 His labeled tag
eMolecules 756525-90-3 | m-PEG8-NHS ester | Broadpharm | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 5g | 698442801
m-PEG8-NHS ester | Broadpharm | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 5g | 698442801
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-NHS (DSPE-NHS) | 1383932-86-2 | MFCD34561791 | 95.0% | 945.2 g/mol | C49H89N2O13P | 10 MG
DSPE-NHS is an N-hydroxysuccinimide (NHS) ester functionalized distearoyl phosphoethanolamine used for bioconjugation and liposome formation. The reagent self-assembles into lipid bilayers in aqueous solution, and the NHS ester reacts selectively with primary amines to form stable amide bonds, enabling antibody labeling and attachment of amine-containing molecules for nanoparticle and drug-delivery applications.
- Reactive NHS ester for covalent coupling to primary amines.
- Self-assembles into lipid bilayers in aqueous solution.
- Enables antibody labeling and protein conjugation.
- Suitable for liposome and nanocarrier preparation.
- Long-term storage recommended at -20 °C, sealed and protected from moisture and light.
Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 50 MG
Biotin-PEG5-NHS ester | 98.0% | 632.72 | 50 MG
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 g/mol | C10H16N2O3S | 10 MG
L-biotin is the unnatural enantiomer of biotin provided as a research-grade chemical standard for stereochemical studies and analytical applications. It is supplied with a certificate of analysis and a safety data sheet to support safe handling and quality verification.
- high reported purity suitable for analytical use
- available in small milligram pack sizes for research
- comes with COA and SDS documentation
- chemical formula C10H16N2O3S and molecular weight 244.31 g/mol
- intended for research use only; not for human use