Biotin and derivatives
Medchemexpress LLC NSP-SA-NHS | 199293-83-9 | 99.65% | 100 MG
NSP-SA-NHS is an acridinium ester used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay for Bisphenol A (BPA) has been developed using NSP-SA-NHS-labeled. It is for research use only.
- Used for chemiluminescent immunoassay.
- Enabled the development of a rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA).
Medchemexpress LLC Mal-PEG8-NHS ester | 2055033-05-9 | 99.0% | 100 MG
Mal-PEG8-NHS ester is a PEG-based PROTAC linker primarily utilized in the synthesis of PROTACs. PROTACs are innovative molecules designed to exploit the ubiquitin-proteasome system, selectively degrading target proteins by linking an E3 ubiquitin ligase ligand to a target protein ligand.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed to selectively degrade target proteins
- For research use only
eMolecules 756525-90-3 | m-PEG8-NHS ester | Ambeed | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 714088003
m-PEG8-NHS ester | Ambeed | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 714088003
Medchemexpress LLC DOTA-NHS-ester TFA | 95.0% | 10 MG
DOTA-NHS-ester (TFA) is a chemical linker used for affibody molecules. It finds applications in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. This product is also suitable for labeling radiotracers or imaging probes for tumor detection.
- Utilized as a linker for affibody molecules
- Applied in small animal positron emission tomography (PET)
- Applied in single photon emission computed tomography (SPECT)
- Applied in CT scanning
- Used to label radiotracers
- Used to label imaging probes for tumor detection
Medchemexpress LLC m-PEG24-NHS ester | 2395839-96-8 | 99.7% | 25 MG
m-PEG24-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins, offering a novel approach in therapeutic development. This product is intended for research use only and is supplied as a white to off-white solid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Stable under recommended storage conditions
Apexbio Technology LLC Cy5 NHS ester(Et) 25mg
Cy5 NHS ester (Et) is an amino-reactive fluorescent dye broadly utilized in biomedical research for labeling proteins peptides and antibodies via covalent conjugation to primary amines The reactive N-hydroxysuccinimidyl ester group specifically binds free amino groups forming stable conjugates suitable for fluorescence imaging and spectroscopic assays Its excitation and emission wavelengths (approximately 646 nm/662 nm) in the far-red spectrum enable compatibility with standard fluorescence microscopy techniques and flow cytometry Cy5 NHS ester (Et) conjugates are routinely employed in applications such as cellular imaging receptor-ligand binding assays protein localization studies and investigation of biomolecular interactions within research laboratory contexts
Medchemexpress LLC BHQ-2 NHS | 916753-62-3 | 97.7% | 603.58 | 5 MG
BHQ-2 NHS is a dark quencher lacking native emission, attributed to its polyaromatic-azo backbone and a terminal NHS ester. It features a broad and intense quenching range from 560-670 nm, making it suitable for fluorescence resonance energy transfer (FRET) applications when used with orange to far-red emitting dyes. The NHS ester allows for labeling of primary amines (-NH2) on proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Dark quencher with no native emission.
- Polyaromatic-azo backbone and a terminal NHS ester.
- Wide and intense quenching range from 560-670 nm.
- Useful as an acceptor in FRET applications.
- Can label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- For research use only.
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 25 MG
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. It quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is also used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads. In vitro, it shows good reactivity with human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), making it appropriate for identifying organophosphorus toxicants reactive proteins.
- Potent organophosphorus toxicant
- Suitable for identifying new biomarkers of organophosphorus toxicant exposure
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Used in plasma studies for easy purification of biotinylated peptides
- Exhibits good reactivity with human AChE and BChE
- Appropriate for identifying organophosphorus toxicant-reactive proteins
Medchemexpress LLC Amine-PEG3-Biotin | 359860-27-8 | 99.8% | 418.55 | 50 MG
Amine-PEG3-Biotin is a signal amplification label that contains a biotin group and a terminal primary amine group, intended for research use only.
- Contains a biotin group and a terminal primary amine group.
- Appears as a white to off-white solid.
- Store at -20°C, protected from light. If in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Soluble in H2O at 200 mg/mL (477.84 mM) and DMSO at 100 mg/mL (238.92 mM), with sonication required.
Medchemexpress LLC N-piperidine Ibrutinib hydrochloride | 2231747-18-3 | 98.1% | 50 MG
N-piperidine Ibrutinib hydrochloride is a reversible Ibrutinib derivative and a potent BTK inhibitor. It can be used as a BTK ligand in the synthesis of various PROTACs.
- Potent BTK inhibitor with IC50s of 51.0 nM for WT BTK and 30.7 nM for C481S BTK.
- Can be used as a BTK ligand in the synthesis of PROTACs.
- Enables synthesis of potent PROTAC BTK degraders.
Medchemexpress LLC m-PEG15-NHS ester | 98.0% | 100 MG
m-PEG15-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. These Proteolysis Targeting Chimeras consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 875.99 and a chemical formula of C39H73NO20. It appears as a white to off-white solid below 35°C and a liquid above 35°C.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 875.99
- Chemical formula: C39H73NO20
- Appears as a white to off-white solid below 35°C
- Liquid above 35°C
- Store at -20°C in sealed storage, away from moisture and light
- In solvent, stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC BHQ-2 NHS | 916753-62-3 | 97.7% | 603.58 | 50 MG
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. It has a wide and intense quenching range from 560-670 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications with orange to far-red emitting dyes. The NHS ester can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester.
- Wide and intense quenching range from 560-670 nm.
- Useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes.
- NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Sigma Aldrich Fine Chemicals Biosciences N-(+)-Biotinyl-6-aminohexanoic acid >=97.0% (HPLC) | 72040-64-3 | MFCD00144853 | 500MG
N-(+)-Biotinyl-6-aminohexanoic acid >=97.0% (HPLC) | Purity: >=97.0% (HPLC) | Mol Wt: 357.47 | 72040-64-3 | MFCD00144853 | 500MG
Medchemexpress LLC Biotin-SLC | 1864003-57-5 | ≥97.0% | 100 MG
Biotin-SLC is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other for the target protein. They function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used for PROTAC synthesis
- Exploits the intracellular ubiquitin-proteasome system for selective protein degradation
- Molecular weight: 427.60
- Molecular formula: C₂₁H₃₇N₃O₄S
- Purity: ≥97.0%
- Appearance: Solid, white to off-white
- Storage at 4°C under nitrogen; in solvent: -80°C for 6 months or -20°C for 1 month under nitrogen
Sigma Aldrich Fine Chemicals Biosciences N-(+)-Biotinyl-6-aminohexanoic acid >=97.0% (HPLC) | 72040-64-3 | MFCD00144853 | 100MG
N-(+)-Biotinyl-6-aminohexanoic acid >=97.0% (HPLC) | Purity: >=97.0% (HPLC) | Mol Wt: 357.47 | 72040-64-3 | MFCD00144853 | 100MG