Dithiolanes
eMolecules 15120-47-5 | AstaTech | 2-METHYLISOPHTHALIC ACID | 0.25g | 342854209 | 35863 | 95 | MFCD00157035 | 180.159 | C9H8O4
Ambeed | N-(2-Fluoro-6-(4455-tetramethyl-132-dioxaborolan-2-yl)benzyl)ethanamine | 250mg | 721418830 | A989597 | 2096341-80-7 | MFCD20529513 | 279.160 | C15H23BFNO2
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Medchemexpress LLC 1,2-Dithiolane-3-pentanoic acid, 2,5-dioxo-1-pyrrolidinyl ester | 40846-94-4 | 98.0% | C12H17NO4S2 | 1 G
α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system. They achieve this by connecting two ligands with a linker: one targeting an E3 ubiquitin ligase and the other binding to the protein of interest. This product is for research use only.
- Alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 40846-94-4 | alpha-lipoic acid-NHS | Broadpharm | MFCD09028032 | 303.390 | C12H17NO4S2 | 98.000 | O=C(CCCCC1CCSS1)ON1C(=O)CCC1=O | 500mg | 268504916
alpha-lipoic acid-NHS | Broadpharm | 40846-94-4 | MFCD09028032 | 303.390 | C12H17NO4S2 | 98.000 | O=C(CCCCC1CCSS1)ON1C(=O)CCC1=O | 500mg | 268504916
Selleck Chemical LLC Thioctic acid S3996-25mg
Thioctic acid (DL- -Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form
Medchemexpress LLC α-Lipoic Acid sodium (Thioctic acid sodium) | 2319-84-8 | 228.31 | 500 MG
α-Lipoic Acid sodium (Thioctic acid sodium) is a potent antioxidant that acts as an essential cofactor for mitochondrial enzyme complexes. It plays a role in cellular processes, inhibiting NF-κB-dependent HIV-1 LTR activation and inducing endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.
- Potent antioxidant properties
- Essential cofactor of mitochondrial enzyme complexes
- Inhibits NF-κB-dependent HIV-1 LTR activation
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells
- Can be used to construct self-assembled nanoaggregates for improved antitumor efficacy
Apexbio Technology LLC Lipoic acid 62-46-4 500mg
Lipoic acid (CAS nan) is a small-molecule organosulfur compound that acts as an essential cofactor for mitochondrial enzymes notably the pyruvate dehydrogenase and -ketoglutarate dehydrogenase complexes which are crucial in energy metabolism pathways Lipoic acid exerts its biological activity primarily through its antioxidant mechanism scavenging reactive oxygen species (ROS) and regenerating endogenous antioxidants to support redox homeostasis and cellular protection mechanisms Based on these pharmacological properties lipoic acid holds research potential in oxidative stress studies mitochondrial dysfunction assays metabolic disease exploration and cell signaling pathway analyses
Medchemexpress LLC α-Lipoic Acid (Thioctic acid) | 1077-28-7 | MFCD00005474 | 206.33 | 1 ML
α-Lipoic Acid (Thioctic acid) is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 (HY-151802) to form self-assembled nanoaggregate CPUL1-LA NA, which shows improved antitumor efficacy compared to CPUL1. This product is for research use only.
- Plays an essential role in mitochondrial bioenergetics.
- Reduces lipid accumulation in the liver.
- Increases NAD+/NADH ratio in HepG2 cells.
- Increases SIRT1 activity in HepG2 cells.
- Increases phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in HepG2 cells.
- Markedly reduces visceral fat mass in C57BL/6J mice.
- Inhibits appetite and causes significant weight loss in mice.
Medchemexpress LLC Ethyl methyl adipate | 18891-13-9 | MFCD34596198 | 25mg
Lipoic acid impurity 1 is an impurity of Lipoic acid (HY-18733)