Dithiolanes
Medchemexpress LLC Alpha-lipoic acid-NHS | 40846-94-4 | 98.0% | C12H17NO4S2 | 250 MG
Alpha-lipoic acid-NHS is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. This compound has a molecular weight of 303.40 and is a white to yellow solid, intended for research use only.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Molecular weight of 303.40
- Appears as a white to yellow solid
- Shipping at room temperature (continental US)
- Storage at -20°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Solubility in ethanol: 2 mg/mL (6.59 mM) with ultrasonic and warming to 60°C
eMolecules Key Organics/BIONET Alpha Lipoic acid 2mg 564364730 KS-1322 97 000 1077-28-7 MFCD00005474 206 320 C8H14O2S2
Key Organics/BIONET Alpha Lipoic acid 2mg 564364730 KS-1322 97 000 1077-28-7 MFCD00005474 206 320 C8H14O2S2
Cayman Chemical R-a-LIpoIc AcId 10g
A cyclic disulfide antioxidant; acts as a cofactor in 2-oxo dehydrogenase complex reactions and is reduced to DHLA; decreases serum levels of MDA and increases the activity of SOD and T-AOC in a mouse model of D-galactose-induced accelerated senescence at 100 mg/kg per day; reduces the escape latency in the Morris water maze compared to both D-galactose and vehicle control groups and rescues decreases in neural progenitor cell proliferation in the hippocampal dentate gyrus at 100 mg/kg per day
Medchemexpress LLC Alpha-lipoic acid | 1077-28-7 | MFCD00005474 | 10 MG
Analytical standard of α-lipoic acid supplied as a 10 mg reference material for research and analytical applications. Suitable for assay, calibration, and analytical method development. CAS number 1077-28-7; molecular weight 206.33; molecular formula C8H14O2S2.
- Supplied as a 10 mg reference material for analytical use.
- Suitable for assay calibration and method validation.
- Provides molecular and CAS identification for traceability.
- Intended for research and analytical applications, including method development.
Selleck Chemical LLC Thioctic acid S3996-25mg
Thioctic acid (DL- -Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form
eMolecules Key Organics/BIONET Alpha Lipoic acid 1mg 564364729 KS-1322 97 000 1077-28-7 MFCD00005474 206 320 C8H14O2S2
Key Organics/BIONET Alpha Lipoic acid 1mg 564364729 KS-1322 97 000 1077-28-7 MFCD00005474 206 320 C8H14O2S2
eMolecules Medchem Express (US) -Lipoic Acid (Standard) 50mg 849677494 HY-N0492R 1077-28-7 MFCD00005474 206 320 C8H14O2S2
Medchem Express (US) -Lipoic Acid (Standard) 50mg 849677494 HY-N0492R 1077-28-7 MFCD00005474 206 320 C8H14O2S2
Cayman Chemical R-a-LIpoIc AcId 5g
A cyclic disulfide antioxidant; acts as a cofactor in 2-oxo dehydrogenase complex reactions and is reduced to DHLA; decreases serum levels of MDA and increases the activity of SOD and T-AOC in a mouse model of D-galactose-induced accelerated senescence at 100 mg/kg per day; reduces the escape latency in the Morris water maze compared to both D-galactose and vehicle control groups and rescues decreases in neural progenitor cell proliferation in the hippocampal dentate gyrus at 100 mg/kg per day
Medchemexpress LLC Ethyl methyl adipate | 18891-13-9 | MFCD34596198 | 25mg
Lipoic acid impurity 1 is an impurity of Lipoic acid (HY-18733)
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.5% | C8H6O5 | 25 MG
4-Hydroxyisophthalic acid activates antioxidant enzymes, such as catalase (CAT) and superoxide dismutase (SOD), scavenges free radicals, and exhibits antioxidant property. It also activates AChE and BChE, enhancing neuronal function and improving Tau-induced neurobehavioral defects. Additionally, it improves cognitive defects and ameliorates circadian rhythm disorders in fruit flies.
- Activates antioxidant enzymes (CAT and SOD)
- Scavenges free radicals
- Exhibits antioxidant properties
- Enhances neuronal function
- Improves Tau-induced neurobehavioral defects
- Ameliorates circadian rhythm disorders
- Molecular weight: 182.13
- Appearance: Solid
- Color: Off-white to pink
- Structure classification: Ketones, aldehydes, acids
- Derived from plants Apocynaceae Decalepis hamiltonii Wight & Arn.
- For research use only
Medchemexpress LLC Isophthalic-2,4,5,6 Acid-d4 | 148472-48-4 | 99.7% | 170.16 | 5 MG
Isophthalic-2,4,5,6 Acid-d4 is the deuterium labeled Isophthalic acid. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium substitution can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Isophthalic-2,4,5,6 acid-d4 | 148472-48-4 | MFCD00209746 | 99.7% | 170.16 g/mol | C8H2D4O4 | 10 MG
Isophthalic-2,4,5,6 Acid-d4 is the deuterium-labeled analogue of isophthalic acid supplied as a solid stable-isotope standard for analytical and tracer applications. It is intended for use as an internal standard in quantitative NMR, GC-MS, and LC-MS assays and for tracer studies requiring deuterium labeling.
- Deuterium-labeled for tracer and internal standard applications.
- Suitable as an internal standard for quantitative NMR, GC-MS, and LC-MS.
- Supplied as a solid powder for convenient handling and storage.
- High chemical purity of 99.7% for reliable analytical performance.
- Stable when stored under recommended conditions to maintain integrity.
eMolecules AstaTech / 2-METHYLISOPHTHALIC ACID / 0.25g / 342854209 / 35863 / 95.000 / 15120-47-5 / MFCD00157035 / 180.159 / C9H8O4
AstaTech / 2-METHYLISOPHTHALIC ACID / 0.25g / 342854209 / 35863 / 95.000 / 15120-47-5 / MFCD00157035 / 180.159 / C9H8O4
Abcam D,L-Thioctic acid (DL-alpha-Lipoic acid), Non-specific free radical scavenger, 25G
MW 206.3 Da, Purity >98%. Non-specific free radical scavenger. Prevents lipid peroxidation and promotes mitochondrial permeability transition in vitro. Anti-oxidant. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement