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Lipoic acid (CAS nan) is a small-molecule organosulfur compound that acts as an essential cofactor for mitochondrial enzymes notably the pyruvate dehydrogenase and -ketoglutarate dehydrogenase complexes which are crucial in energy metabolism pathways Lipoic acid exerts its biological activity primarily through its antioxidant mechanism scavenging reactive oxygen species (ROS) and regenerating endogenous antioxidants to support redox homeostasis and cellular protection mechanisms Based on these pharmacological properties lipoic acid holds research potential in oxidative stress studies mitochondrial dysfunction assays metabolic disease exploration and cell signaling pathway analyses
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